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acyl chloride derivative

" in MedChemExpress (MCE) Product Catalog:

25

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2

Biochemical Assay Reagents

4

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Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-41982
    D-Glucuronic acid lactone
    1 Publications Verification

    D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone

    		 Environmental Pollutants Endogenous Metabolite Drug Derivative Cardiovascular Disease Metabolic Disease
    D-Glucuronic acid lactone (D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone) is an endogenous metabolite and a glucuronic acid derivative. D-Glucuronic acid lactone serves as a starting reagent for the synthesis of 2,3,4-tris (tert-butyldimethylsilyl) glucuronic acid trichloroethyl ester, which is used to prepare 1-O-acyl glucuronic acids for the anti-inflammatory agent mL-3000 (HY-B1452), synthesize optically active glucuronic acids, and produce long-chain alkyl glucuronides. D-Glucuronic acid lactone shows potential for use in studies of reversible cerebral vasoconstriction syndrome (RCVS) .
    D-Glucuronic acid lactone
  • HY-Y0925
    5-Hexynoic acid

    Hex-5-ynoic acid

    		 Drug Intermediate PROTAC Linkers Others
    5-Hexynoic acid (Hex-5-ynoic acid) is an alkynoic acid. 5-Hexynoic acid serves as a drug intermediate for the synthesis of 3-alkoxy-2-cyclohexenone .
    5-Hexynoic acid
  • HY-CE02017
    trans-Feruloyl-CoA

    trans-Feruloyl-coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    trans-Feruloyl-CoA (trans-Feruloyl-coenzyme A) is a derivative of coenzyme A. trans-Feruloyl-CoA also acts as an activated acyl donor involved in the synthesis of cell wall components such as lignin and feruloylated polysaccharides .
    trans-Feruloyl-CoA
  • HY-113089
    Epsilon-(gamma-glutamyl)-lysine

    H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys

    		 Endogenous Metabolite Metabolic Disease
    Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
    Epsilon-(gamma-glutamyl)-lysine
  • HY-116284
    Methyl β-D-glucopyranoside

    Methyl β-D-glucoside

    		 Drug Intermediate Others
    Methyl β-D-glucopyranoside (Methyl β-D-glucoside) is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside can generate biologically active derivatives (such as 6-O-caffeoyl glucoside). Methyl β-D-glucopyranoside can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside) .
    Methyl β-D-glucopyranoside
  • HY-Y0549
    Diphenylacetic acid

    Diphenylmethane-α-carboxylic Acid

    		 Biochemical Assay Reagents Others
    Diphenylacetic acid (Diphenylmethane-α-carboxylic Acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diphenylacetic acid can be used as a reagent in the kinetic resolution of racemic 2-hydroxy-y-butyrolactones by asymmetric esterification in the presence of pivalic anhydride and chiral acyl-transfer catalyst. Diphenylacetic acid can act as a catalyst to synthesize 2-allyl-3-oxazolin-5-one derivatives via Rh-catalyzed coupling reaction of azlactones and alkynes followed by aza-Cope rearrangement .
    Diphenylacetic acid
  • HY-W015800
    L-Homoserine lactone hydrochloride

    		Drug Intermediate Others
    L-Homoserine lactone hydrochloride is the core structural unit of the bacterial quorum-sensing signal molecule N-acyl-L-homoserine lactone (AHLs). As an important intermediate, L-Homoserine lactone hydrochloride acylated derivatives have potent immunosuppressive activity .
    L-Homoserine lactone hydrochloride
  • HY-W322225
    1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine

    DLPE; 1,2-Dilauroyl-sn-glycero-3-PE

    		 Liposome Others
    1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a derivative of phosphatidylethanolamine with lauric acid (12:0) acyl chains. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine can be used to synthesize liposomes .
    1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine
  • HY-113089A
    Epsilon-(gamma-glutamyl)-lysine TFA

    H-Glu(H-Lys-OH)-OH TFA; γ-Glu-ε-Lys TFA

    		 Endogenous Metabolite Metabolic Disease
    Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
    Epsilon-(gamma-glutamyl)-lysine TFA
  • HY-122643
    NITD-916

    		Bacterial Infection
    NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active mycobacterial enoyl reductase InhA inhibitor with an IC50 of 570 nM. NITD-916 forms a ternary complex with InhA and NADH to block access to the fatty acyl substrate binding pocket. NITD-916 inhibition of InhA reduces the synthesis of mycolic acids and results in cell death. NITD-916 has potent anti-tuberculosis effects .
    NITD-916
  • HY-W014674
    2,6-Dichlorophenylacetic acid

    		Acyltransferase Cancer
    2,6-Dichlorophenylacetic acid is an inhibitor of isopenicillin N synthase (IPNS) and acyl-CoA: 6-APA acyltransferase. 2,6-Dichlorophenylacetic acid is also part of a group of phenylacetate derivatives that have cytostatic activity against tumour cells .
    2,6-Dichlorophenylacetic acid
  • HY-W012802
    Methyl 1H-pyrrole-2-carboxylate

    		Drug Intermediate Others
    Methyl 1H-pyrrole-2-carboxylate is a drug intermediate that can act as an acyl donor. Methyl 1H-pyrrole-2-carboxylate can be synthesized into a series of pyrrolidine derivatives through tranesterification reactions with various alcohols .
    Methyl 1H-pyrrole-2-carboxylate
  • HY-130405
    PtdIns-(1,2-dipalmitoyl) ammonium

    		Drug Derivative Metabolic Disease
    PtdIns-(1,2-dipalmitoyl) ammonium (DPPI) is a derivative of phosphatidylinositol (PtdIns) that contains C16:0 fatty acyl chains .
    PtdIns-(1,2-dipalmitoyl) ammonium
  • HY-134129
    Benzoyl coenzyme A

    Benzoyl CoA

    		 Endogenous Metabolite Others Metabolic Disease
    Benzoyl coenzyme A (Benzoyl CoA) is A derivative of Coenzyme A (CoA) in which the mercaptan group of CoA binds to the benzoyl group. Benzoyl coenzyme A is involved in the catalytic reaction as a substrate for the acyl transfer reaction. Benzoyl coenzyme A is a versatile metabolic intermediate that can be used to reveal substrate specificity of enzymes, metabolic regulation, and drug metabolism .
    Benzoyl coenzyme A
  • HY-113089AR
    Epsilon-(gamma-glutamyl)-lysine TFA (Standard)

    H-Glu(H-Lys-OH)-OH TFA (Standard); γ-Glu-ε-Lys TFA (Standard)

    		 Endogenous Metabolite Reference Standards Metabolic Disease
    Epsilon-(gamma-glutamyl)-lysine (TFA) (Standard) is the analytical standard of Epsilon-(gamma-glutamyl)-lysine (TFA). This product is intended for research and analytical applications. Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .
    Epsilon-(gamma-glutamyl)-lysine TFA (Standard)
  • HY-W347540
    oxy-Arachidonoyl ethanolamide

    O-alkyl-N-acylhydroxylamine

    		 Endogenous Metabolite Others
    oxy-Arachidonoyl ethanolamide (O-alkyl-N-acylhydroxylamine) is an O-alkyl-N-acyl oxime derivative .
    oxy-Arachidonoyl ethanolamide
  • HY-N11421
    23-O-Demycinosyltylosin

    23-DMT; 23-Demycinosyltylosin

    		 Bacterial Infection
    23-O-Demycinosyltylosin (23-DMT) is a 23-O-demycinosyltylosin (DMT) acyl derivative with antibacterial activity .
    23-O-Demycinosyltylosin
  • HY-160678
    InhA-IN-7

    		Bacterial Infection
    InhA-IN-7 (Compound 11) is a Triclocan (HY-B1119) derivative with inhibitory activity towards enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. InhA-IN-7 inhibits proliferations of Mycobacterium tuberculosis wildtype and mutant strains with MICs ranging from 19 to 75 μM .
    InhA-IN-7
  • HY-119001
    BKM1644

    		Survivin Cancer
    BKM1644, an acyl-tyrosine bisphosphonate amide derivative, exhibits potent anti-cancer activity. BKM1644 effectively inhibits the proliferation of metastatic, castration-resistant prostate cance (mCRPC) cells. BKM1644 sensitizes mCRPC cells to Docetaxel (HY-B0011) and retards the bone metastatic growth of prostate cance .
    BKM1644
  • HY-134129B
    Benzoyl coenzyme A sodium

    Benzoyl CoA sodium

    		 Endogenous Metabolite Others Metabolic Disease
    Benzoyl coenzyme A (sodium) is the sodium salt form of Benzoyl coenzyme A (HY-134129). Benzoyl coenzyme A (sodium) is A derivative of Coenzyme A (CoA) in which the mercaptan group of CoA binds to the benzoyl group. Benzoyl coenzyme A (sodium) is involved in the catalytic reaction as a substrate for the acyl transfer reaction. Benzoyl coenzyme A (sodium) is a versatile metabolic intermediate that can be used to reveal substrate specificity of enzymes, metabolic regulation, and drug metabolism .
    Benzoyl coenzyme A sodium
  • HY-E70274
    17:1(n7) Coenzyme A triammonium

    		Others Metabolic Disease
    17:1(n7) Coenzyme A triammonium is a derivative of fatty acyl-CoA .
    17:1(n7) Coenzyme A triammonium
  • HY-186081
    Ramiprilat acyl-β-D-glucuronide

    		Drug Metabolite Metabolic Disease
    Ramiprilat acyl-β-D-glucuronide is an acyl glucuronide metabolite of Ramiprilat (HY-B0279). Ramiprilat acyl-β-D-glucuronide undergoes methylation on its glucuronic acid moiety during solid phase extraction with strong cation exchanger cartridges, forming a methylated derivative. Ramiprilat acyl-β-D-glucuronide undergoes in-source conversion to Ramiprilat in mass spectrometry, with conversion extent proportional to declustering potential voltage .
    Ramiprilat acyl-β-D-glucuronide
  • HY-N14982
    Ferrimycin A1

    		Antibiotic Infection Inflammation/Immunology
    Ferrimycin A1 is an iron-containing peptide antibiotic and an acyl derivative of ferrimycin B, a competitive antagonist and microbial growth factor .
    Ferrimycin A1
  • HY-170470
    1,2-Diarachidoyl-rac-glycerol

    DG(20:0/20:0/0:0)

    		 Biochemical Assay Reagents Others
    1,2-Diarachidoyl-rac-glycerol (DG(20:0/20:0/0:0)) is a diacylglycerol in which both acyl groups are acyl groups of arachidonic acid. 1,2-Diarachidoyl-rac-glycerol can be used to enhance the skin barrier function and maintain the moisture and lipid balance of the skin as a diacylglycerol derivative .
    1,2-Diarachidoyl-rac-glycerol
  • HY-N15775
    Ace-1

    Azo-Cer

    		 Biochemical Assay Reagents Others
    ACe-1 is a ceramide derivative with an azobenzene moiety to allow for optical control of the N-acyl chain. ACe-1 is capable of reversibly switching lipid domains in a raft-like bilayer membrane .
    Ace-1

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