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adenine phosphoribosyl transferase

" in MedChemExpress (MCE) Product Catalog:

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-113291
    5'-Deoxyadenosine
    2 Publications Verification

    		 Nucleoside Antimetabolite/Analog Phosphorylase Others
    5'-Deoxyadenosine is a 5'-methylthioadenosine phosphorylase substrate and deoxyadenosine. 5'-Deoxyadenosine serves as a non-metabolizable substrate for nucleoside transport assays only in cells lacking 5'-methylthioadenosine phosphorylase .
    5'-Deoxyadenosine
  • HY-172919
    PDEδ/NAMPT IN-1

    		Phosphodiesterase (PDE) NAMPT Apoptosis Cancer
    PDEδ/NAMPT IN-1 (Compound 17d) is a dual inhibitor targeting phosphodiesterase 6 (PDE6) (KD=0.410 nM) and nicotinamide phosphoribosyl transferase (NAMPT) (IC50=2.21 nM). PDEδ/NAMPT IN-1 blocks KRAS-related signal transduction and interferes with the synthesis of nicotinamide adenine dinucleotide (NAD +), inducing apoptosis in KRAS mutant pancreatic cancer cells. PDEδ/NAMPT IN-1 is promising for research of KRAS mutant pancreatic cancer .
    PDEδ/NAMPT IN-1

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