24 Results for "

adenosine deaminase (ADA)

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "adenosine deaminase (ADA)" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-103160A
CAS No.: 58337-38-5
Purity:  99.67%
EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects .
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2
2 Cited Publications
Cat. No.: HY-W011552R
CAS No.: 2140-79-6
2'-O-Methyladenosine (Standard) is the analytical standard of 2'-O-Methyladenosine. This product is intended for research and analytical applications. 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
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Cat. No.: HY-103237
CAS No.: 3080-29-3
Purity:  99.82%
Target:  

Adenosine Deaminase

Research Areas:  

Neurological Disease

L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an Ki value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation .
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Cat. No.: HY-N7368
CAS No.: 55366-56-8
Hibifolin is a flavonol glycoside that can be isolated from Helicteres isora. Hibifolin is an inhibitor of adenosine deaminase (ADA) (Ki = 49.92 μM). Hibifolin protects neurons against β-amyloid-induced neurotoxicity. Hibifolin possesses a potent protective activity against cell death induced by aggregated Aβ. Hibifolin can abolish Aβ-induced caspase-3 and caspase-7 activation. Hibifolin induces Akt phosphorylation in cortical neurons. Hibifolin is also a natural sortase A (SrtA) inhibitor (IC50 = 31.2 μM) through direct binding to SrtA protein. Hibifolin attenuates the pathogenic behavior of Staphylococcus aureus including adhesion, invasion, and biofilm formation. Hibifolin improves the survival of pneumonia induced by Staphylococcus aureus in mouse model and alleviates pathological damage. Hibifolin shows a synergistic antibacterial effect with Cefotaxime (HY-A0088A) .
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Cat. No.: HY-W011552
CAS No.: 2140-79-6
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
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Cat. No.: HY-103159
CAS No.: 14432-09-8
Purity:  ≥98.0%
Target:  

Adenosine Deaminase

Research Areas:  

Cancer

1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders .
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Cat. No.: HY-105017
CAS No.: 844873-47-8
Purity:  99.74%
Synonyms: ATL 313; DE 112
Target:  

Adenosine Receptor

Research Areas:  

Infection Inflammation/Immunology

Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenoson’s primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenoson’s protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α) .
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Cat. No.: HY-D0855A
CAS No.: 41689-31-0
ADA (disodium) is a buffer salt derived from ADA (adenosine deaminase) and is widely used in biochemical research, especially in the preparation of enzyme buffers.
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Cat. No.: HY-19130
CAS No.: 143153-93-9
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease

BW-534U87 is an orally active adenosine A1 receptor agonist and competitive adenosine deaminase (ADA) inhibitor (Ki=7 μM). BW-534U87 elevates brain adenosine levels and suppresses epileptiform activity. BW-534U87 demonstrate anticonvulsant efficacy in animal seizure models. BW-534U87 is promising for research of epilepsy and adenosine-related neuropsychiatric disorders .
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Cat. No.: HY-103160B
CAS No.: 51350-19-7
EHNA is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects .
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Cat. No.: HY-103237R
CAS No.: 3080-29-3
L-Adenosine (Standard) is the analytical standard of L-Adenosine (HY-103237). This product is intended for research and analytical applications. L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an Ki value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation .
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Cat. No.: HY-133216
CAS No.: 41483-43-6
Purity:  99.77%
Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew .
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Cat. No.: HY-W753672
CAS No.: 1195030-24-0
2'-O-Methyl Adenosine-d3 is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities .
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Cat. No.: HY-133216R
CAS No.: 41483-43-6
Research Areas:  

Infection

Bupirimate (Standard) is the analytical standard of Bupirimate (HY-133216). This product is intended for research and analytical applications. Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew .
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Cat. No.: HY-P74429
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADA; adenosine Aminohydrolase; adenosine deaminase; Mutant adenosine deaminase; ADA1
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-N7368R
CAS No.: 55366-56-8
Hibifolin (Standard) is the analytical standard of Hibifolin. This product is intended for research and analytical applications. Hibifolin is a flavonol glycoside that can be isolated from Helicteres isora. Hibifolin is an inhibitor of adenosine deaminase (ADA) (Ki = 49.92 μM). Hibifolin protects neurons against β-amyloid-induced neurotoxicity. Hibifolin possesses a potent protective activity against cell death induced by aggregated Aβ. Hibifolin can abolish Aβ-induced caspase-3 and caspase-7 activation. Hibifolin induces Akt phosphorylation in cortical neurons. Hibifolin is also a natural sortase A (SrtA) inhibitor (IC50 = 31.2 μM) through direct binding to SrtA protein. Hibifolin attenuates the pathogenic behavior of Staphylococcus aureus including adhesion, invasion, and biofilm formation. Hibifolin improves the survival of pneumonia induced by Staphylococcus aureus in mouse model and alleviates pathological damage. Hibifolin shows a synergistic antibacterial effect with Cefotaxime (HY-A0088A) .
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Cat. No.: HY-P82862
Synonyms: ada; ADA1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Rat

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Cat. No.: HY-P810451
Synonyms: ada, ADA1

Host:  

Rabbit

Application:  

WB, ICC/IF, IP

Reactivity:  

Human, Rat

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Cat. No.: HY-P82862A
Synonyms: ada; ADA1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Rat

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Cat. No.: HY-P76250
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ADA2; Cat Eye Syndrome Chromosome Region, Candidate 1; Prev. CECR1; adenosine deaminase; Prev. IDGFL; SNEDS; ADGF; VAIHS; Cat Eye Syndrome Critical Region Protein 1; PAN; adenosine deaminase 2; adenosine deaminase CECR1
Species:  
Human
Source:  
Sf9 insect cells
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