143153-93-9
Chemical Structure
BW-534U87
- CAS No.: 143153-93-9
- Formula:C12H10ClF2N5
- Molecular Weight:297.69
IUPAC Name: 1-(2,6-difluorobenzyl)-1H-[1,2,3]triazolo[4,5-c]pyridin-4-amine hydrochloride
InChIKey: JKXUBXRPDZPXOD-UHFFFAOYSA-N
SMILES: FC1=CC=CC(F)=C1CN2N=NC3=C2C=CN=C3N.Cl
Biological Activity: BW-534U87 is an orally active adenosine A1 receptor agonist and competitive adenosine deaminase (ADA) inhibitor (Ki=7 μM). BW-534U87 elevates brain adenosine levels and suppresses epileptiform activity. BW-534U87 demonstrate anticonvulsant efficacy in animal seizure models. BW-534U87 is promising for research of epilepsy and adenosine-related neuropsychiatric disorders[1].
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BW-534U87 | BW-534U87 is an orally active adenosine A1 receptor agonist and competitive adenosine deaminase (ADA) inhibitor (Ki=7 μM). BW-534U87 elevates brain adenosine levels and suppresses epileptiform activity. BW-534U87 demonstrate anticonvulsant efficacy in animal seizure models. BW-534U87 is promising for research of epilepsy and adenosine-related neuropsychiatric disorders. | |||||||||||||||||||||
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Keywords
