844873-47-8
Chemical Structure
Evodenoson
Synonym(s): ATL 313; DE 112
- CAS No.: 844873-47-8
- Formula:C23H29N7O6
- Molecular Weight:499.52
IUPAC Name: methyl 4-(3-(6-amino-9-((2R,3R,4S,5S)-5-(cyclopropylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)prop-2-yn-1-yl)piperidine-1-carboxylate
InChIKey: SQJXTUJMBYVDBB-RQXXJAGISA-N
SMILES: O[C@H]1[C@@H](O[C@@H]([C@H]1O)C(NC2CC2)=O)N3C4=NC(C#CCC5CCN(CC5)C(OC)=O)=NC(N)=C4N=C3
Biological Activity: Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenoson’s primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenoson’s protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α)[1].
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Evodenoson | 99.94% | Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenoson’s primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenoson’s protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α). | ||||||||||||||||||||
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Keywords
