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Results for "

alkaloid extract

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Aldose Reductase (1) Apoptosis (19) Autophagy (7) Bacterial (21) Biochemical Assay Reagents (4) Calcium Channel (1) Caspase (1) Cholinesterase (ChE) (1) Cytochrome P450 (2) Dengue Virus (5) Drug Derivative (2) Drug Intermediate (1) Endogenous Metabolite (1) Fatty Acid Synthase (FASN) (2) FGFR (1) Flavivirus (5) Free Fatty Acid Receptor (2) Fungal (2) Glycosidase (2) IKK (2) Influenza Virus (1) Interleukin Related (2) JNK (2) mAChR (1) Microtubule/Tubulin (2) Mitochondrial Metabolism (1) Mitophagy (1) MMP (1) nAChR (2) NF-κB (11) Opioid Receptor (4) p38 MAPK (2) Parasite (12) PERK (2) Phosphodiesterase (PDE) (1) Potassium Channel (5) RANKL/RANK (2) Reactive Oxygen Species (ROS) (3) Reference Standards (14) Sigma Receptor (1) Virus Protease (2) Wnt (2) α-synuclein (2) β-catenin (2)
By Research Areas:	Cancer (30) Cardiovascular Disease (5) Endocrinology (3) Infection (29) Inflammation/Immunology (52) Metabolic Disease (14) Neurological Disease (26)

By Targets:

Acyltransferase (1)

Aldose Reductase (1)

Apoptosis (19)

Autophagy (7)

Bacterial (21)

Biochemical Assay Reagents (4)

Calcium Channel (1)

Caspase (1)

Cholinesterase (ChE) (1)

Cytochrome P450 (2)

Dengue Virus (5)

Drug Derivative (2)

Drug Intermediate (1)

Endogenous Metabolite (1)

Fatty Acid Synthase (FASN) (2)

FGFR (1)

Flavivirus (5)

Free Fatty Acid Receptor (2)

Fungal (2)

Glycosidase (2)

IKK (2)

Influenza Virus (1)

Interleukin Related (2)

JNK (2)

mAChR (1)

Microtubule/Tubulin (2)

Mitochondrial Metabolism (1)

Mitophagy (1)

MMP (1)

nAChR (2)

NF-κB (11)

Opioid Receptor (4)

p38 MAPK (2)

Parasite (12)

PERK (2)

Phosphodiesterase (PDE) (1)

Potassium Channel (5)

RANKL/RANK (2)

Reactive Oxygen Species (ROS) (3)

Reference Standards (14)

Sigma Receptor (1)

Virus Protease (2)

Wnt (2)

α-synuclein (2)

β-catenin (2)

By Research Areas:

Cancer (30)

Cardiovascular Disease (5)

Endocrinology (3)

Infection (29)

Inflammation/Immunology (52)

Metabolic Disease (14)

Neurological Disease (26)

116

Inhibitors & Agonists

109

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0288

Lycorine Maximum Cited Publications 22 Publications Verification	Fatty Acid Synthase (FASN) Virus Protease Bacterial Apoptosis	Inflammation/Immunology Cancer
Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a K_d value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription . Lycorine is also a melanoma vasculogenic inhibitor . Lycorine can be used for the study of prostate cancer and metabolic diseases .

HY-15122

Sinomenine 15+ Cited Publications	NF-κB Opioid Receptor Autophagy Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Sinomenine, an alkaloid extracted from Sinomenium acutum, is a blocker of the NF-κB activation . Sinomenine also is an activator of μ-opioid receptor .

HY-N2022

Castanospermine 4 Publications Verification	Glycosidase	Inflammation/Immunology Cancer
Castanospermine is a natural alkaloid that can be extracted from black beans or the Moreton Bay chestnut tree (Castanospermum australae). Castanospermine is an α/ β-glucosidase inhibitor. Castanospermine has anti-inflammatory, antiviral replication and anti-metastatic effects on prostate cancer. Castanospermine can be used as an immunosuppressant to prevent transplant rejection .

HY-15122A

Sinomenine hydrochloride 15+ Cited Publications Cucoline hydrochloride	NF-κB Opioid Receptor Autophagy Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Sinomenine hydrochloride (Cucoline hydrochloride), an alkaloid extracted from Sinomenium acutum, is a blocker of the NF-κB activation . Sinomenine also is an activator of μ-opioid receptor .

HY-N0770

Isoliensinine 4 Publications Verification	Apoptosis	Inflammation/Immunology Cancer
Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells .

HY-N0485

Liensinine Diperchlorate 15+ Cited Publications	Autophagy Mitophagy	Cardiovascular Disease
Liensinine Diperchlorate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlorate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlorate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc .

HY-N0687

Vindoline 1 Publications Verification	Microtubule/Tubulin Apoptosis NF-κB PERK	Metabolic Disease Inflammation/Immunology Endocrinology
Vindoline is an orally active vinca alkaloid. Vindoline can be extracted from the leaves of Catharanthus roseus. Vindoline has a weak inhibitory effect on the self-assembly of tubulin. Vindoline alleviates Apoptosis, inhibits p-p65 and p-ERK. Vindoline improves diabetes, bone loss, osteoarthritis, and kidney damage .

HY-W010668

Quinine sulfate hydrate 5+ Cited Publications	Flavivirus Dengue Virus Parasite Potassium Channel	Others
Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-N1089

Vincosamide	Cholinesterase (ChE)	Inflammation/Immunology
Vincosamide, an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity .

HY-N10087

Angustifoline	Bacterial	Infection
Angustifoline, an alkaloid, can be isolated from Lupinus angustifolius L. alkaloid extract. Angustifoline exhibits antimicrobial activity. Angustifoline could have bacteriostatic effects against S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis .

HY-N2197

Hirsuteine 2 Publications Verification	nAChR	Neurological Disease
Hirsuteine is an indole alkaloid extracted from Uncaria rhynchophylla. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes .

HY-N1402

Oxysophoridine Sophoridine N-oxide	Apoptosis	Inflammation/Immunology
Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects .

HY-N0746

Oxysophocarpine 5+ Cited Publications	Others	Cancer
Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides.?Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the?growth?and?metastasis?of ?oral?squamous?cell?carcinoma?(OSCC) .

HY-N0413

Hupehenine	α-synuclein Reactive Oxygen Species (ROS) Apoptosis Autophagy Parasite	Infection Neurological Disease Inflammation/Immunology Cancer
Hupehenine is an orally active isosteroidal alkaloid that can be extracted from F. hupehensis. Hupehenine exhibits activities such as antitussive, expectorant, anticancer, and antiparasitic. In vitro, Hupehenine can also inhibit α-synuclein seeded fibril formation, making it applicable for the research of Parkinson's disease and other related disorders .

HY-N3619

Conophylline 1 Publications Verification	Apoptosis	Neurological Disease Endocrinology
Conophylline is a vinca alkaloid extracted from leaves of a tropical plant Ervatamia microphylla. Conophylline is a differentiation inducer of for pancreatic cells. Conophylline suppresses HSC and induces apoptosis .

HY-D0143A

Quinine dihydrochloride	Flavivirus Dengue Virus Parasite Potassium Channel	Infection
Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-N16535

Stigmalactam	Apoptosis Caspase Mitochondrial Metabolism Reactive Oxygen Species (ROS)	Cancer
Stigmalactam is an aristolactam-type alkaloid extracted from Orophea enterocarpa with anticancer effects. Stigmalactam induces apoptosis via the mitochondrial pathway, with the activation of caspase-3/9, and a decrease in mitochondrial membrane potential (MTP). Stigmalactam exhibits antioxidant activity by decreasing ROS production. Stigmalactam can be used for liver and breast cancer research .

HY-107918

Alkaloids, Rauwolfia	Others	Cardiovascular Disease
Alkaloids, Rauwolfia is an extract of the whole root of Rauwolfia serpentina with antihypertensive effect .

HY-N10955

Dichotomine H	Others	Inflammation/Immunology
Dichotomine H is a P-carboline alkaloid that can be extracted from Stellaria dichotoma L. Dichotomine H has good antiallergic activity .

HY-N8262

Dehydrocorybulbine chloride	Influenza Virus	Infection
Dehydrocorybulbine chloride is an isoquinoline alkaloid with neuraminidase (NA) inhibitory activity. Dehydrocorybulbine chloride can be isolated from the 95% ethanol extract of the rhizome of Viola odorata .

HY-N4307

Laetanine	Parasite	Infection
Laetanine is a noraporphine alkaloid from Litsea laeta, exhibits antiplasmodial activity. Laetanine can be found in the extract of the leaves of Phoebe tavoyana (Meissn) Hook .

HY-15122R

Sinomenine (Standard)	Reference Standards NF-κB Opioid Receptor Autophagy Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Sinomenine (Standard) is the analytical standard of Sinomenine. This product is intended for research and analytical applications. Sinomenine, an alkaloid extracted from?Sinomenium acutum, is a blocker of the NF-κB activation . Sinomenine also is an activator of μ-opioid receptor .

HY-117616

Laurotetanine (+)-Laurotetanine	NF-κB	Cancer
Laurotetanine ((+)-Laurotetanine) is an potent and orally active isoquinoline alkaloid and could be extracted from the roots of Litsea cubeba (Lour.) Pers. Laurotetanine exerts an anti-asthmatic effect by inhibition of IgE, histamine, and inflammatory reactions via down-regulating MUC5AC and NF-κB signaling pathways .

HY-B0433B

Quinine hemisulfate	Flavivirus Dengue Virus Parasite Potassium Channel	Infection
Quinine hemisulfate is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine hemisulfate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-N2022R

Castanospermine (Standard)	Reference Standards Glycosidase	Inflammation/Immunology Cancer
Castanospermine is a natural alkaloid that can be extracted from black beans or the Moreton Bay chestnut tree (Castanospermum australae). Castanospermine is an α/ β-glucosidase inhibitor. Castanospermine has anti-inflammatory, antiviral replication and anti-metastatic effects on prostate cancer. Castanospermine can be used as an immunosuppressant to prevent transplant rejection .

HY-N11922

Ipalbidine	Others	Neurological Disease
Ipalbidine is an alkaloid extracted from ipomoea Hardwickki Hemsl. Ipalbidine has dose-dependent analgesic effects .

HY-N12313

Corybulbine	Aldose Reductase	Metabolic Disease
Corybulbine, an alkaloid that can be isolated from the methanolic extract of Corydalis ternata, is an aldose reductase (ALR2) inhibitor. Corybulbine can be used for diabetic complications research .

HY-123025

Schizozygine	Fungal	Inflammation/Immunology
Schizozygine is an alkaloid that can be isolated from Schizozygia caffaeoides. Schizozygia caffaeoides has been used as a traditional medicine for skin disease. The leaf extracts has high antifungal and antimicrobial activity .

HY-N1251

Scholaricine	Others	Others
Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC₅₀ value of 13.35 μM .

HY-N2926

β-Carboline-1-propionic acid	Parasite	Infection
β-Carboline-1-propionic acid is a alkaloid which can be extracted from Ailanthus altissima. β-Carboline-1-propionic acid can be used as an antileishmanial agent .

HY-N15629

Melicopicine NSC 402921	Biochemical Assay Reagents	Others
Melicopicine (NSC 402921) (Compound 2) is an acridone alkaloid. Melicopicine is a 1,2,3,4-tetraoxygenated acridone precursor, which can be co-isolated from S. megistophylla and detected by GC-MS in the extract from S. follicularis .

HY-N9507

Picrasidine Q	Apoptosis FGFR	Cancer
Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase activity .

HY-N0746R

Oxysophocarpine (Standard)	Reference Standards Others	Cancer
Oxysophocarpine (Standard) is the analytical standard of Oxysophocarpine. This product is intended for research and analytical applications. Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides. Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the growth and metastasis of oral squamous cell carcinoma (OSCC) .

HY-N11979

Dihydronitidine	Others	Others
Dihydronitidine is an alkaloid can be extracted from Zanthoxylum rhoifolium .

HY-119642

Kopsinine	Others	Others
Kopsinine is an indole alkaloid extracted from periwinkle flowers .

HY-N15699

Norcorydine	Biochemical Assay Reagents	Others
Norcorydine is a aporphine alkaloid that can be extracted from the leaves of Annona salzmannii .

HY-N12343

Tetrahydrorhombifoline	Bacterial Fungal	Infection
Tetrahydrorhombifoline is one of quinolizidine alkaloids in the aerial parts of Genista vuralii A. Duran & H. Dural (Fabaceae). The alkaloid extract of G. vuralii has antibacterial and antifungal activities .

HY-N7341

8-Deacetylyunaconitine	Others	Others
8-Deacetylyunaconitine, a diterpenoid alkaloid, can be found in the root extract of A. forrestii .

HY-117034

Rankinidine	Others	Others
Rankinidine is an oxindole alkaloid that is isolated from the MeOH extract of the stem of Gelsemium rankinii .

HY-W194842

Harmalan	Others	Others
Harmalan (compound 8) is a alkaloid isolated from the extracts of the leaves of Flindersia laevicarpa .

HY-N3374

Lochnerine 10-O-Methylsarpagine	Others	Others
Lochnerine is an indole alkaloid can be isolated from the stem bark extract of Alstonia macrophylla .

HY-N15627

Xanthevodine NSC 94652	Others	Others
Xanthevodine (NSC 94652) is an alkaloid that can be extracted from the leaves of Acronychia baueri Schott .

HY-N1019

11-Hydroxyhumantenine N-Methyl-11-hydroxyrankinidine	Others	Others
11-Hydroxyhumantenine is an alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .

HY-N8452

Noroxyhydrastinine	Others	Others
Noroxyhydrastinine (compound 1) is an alkaloid. Noroxyhydrastinine can be isolated from the ethanolic extract of the roots of Thalictrum angustifolium .

HY-N0298A

(±)-Stachydrine	Others	Inflammation/Immunology
(±)-Stachydrine is a quaternary ammonium alkaloid that can be extracted from Courbonia glauca. (±)-Stachydrine can be used for research on inflammatory conditions .

HY-N9537

Napelline	Others	Inflammation/Immunology
Napelline is an alkaloid extracted from Baikal aconite (Aconitum baikalensis). Napelline can be used for the research of inflammation, antiexudative and analgesic .

HY-119637

Frangufoline	Others	Others
Frangufoline is a 4(14)-type cyclopeptide alkaloid, that can be isolated from the root bark extract of Ziziphus cambodiana Pierre .

HY-N0491

(-)-Sparteine sulfate (-)-Lupinidine sulfate	nAChR	Neurological Disease
(-)-Sparteine (sulfate) is a quinolizidine alkaloid that can be extracted from Lupinus. (-)-Sparteine (sulfate) inhibits the release of acetylcholine and has anticonvulsant effects .

HY-168778

(±)-Δ7-Mesembrenone	Endogenous Metabolite	Others
(±)-Δ7-Mesembrenone is a mesembrine-type alkaloid which can be extracted from various Sceletium .

HY-N10087A

Angustifoline hydrochloride	Bacterial	Infection
Angustifoline hydrochloride, an alkaloid, can be isolated from Lupinus angustifolius L. alkaloid extract. Angustifoline hydrochloride exhibits antimicrobial activity. Angustifoline hydrochloride could have bacteriostatic effects against S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis .

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alkaloid extract

Inhibitors & Agonists

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