1. Alkaloid

Castanospermine 

Cat. No.: HY-N2022 Purity: >98.0%
Data Sheet SDS Handling Instructions

Castanospermine inhibits all forms of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids).

For research use only. We do not sell to patients.
Castanospermine Chemical Structure

Castanospermine Chemical Structure

CAS No. : 79831-76-8

Size Price Stock Quantity
10 mM * 1 mL in Water $55 In-stock
10 mg $50 In-stock
50 mg $80 In-stock
100 mg $100 In-stock
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Castanospermine inhibits all forms of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). target:α- and β-glucosidases. IC 50: 1.2 uM [2] in vitro :Castanospermine, [(1 S,6S,7R,8R,8aR)-1 ,6,7,8-tetrahydroxyoctahydroindolizine] is a potent and specific inhibitor of mammalian and plant α-and β-D-glucosidases in vitro [1] in vivo: Experiments in vivo with castanospermine, an inhibitor of the glucosidases that convert protein N-linked high mannose carbohydrates to complex oligosaccharides, resulted in significant inhibition of tumor growth in nude mice.[3]

References
Molecular Weight

189.21

Formula

C₈H₁₅NO₄

CAS No.

79831-76-8

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

H2O: ≥ 34 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Castanospermine
Cat. No.:
HY-N2022
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