1. Alkaloid
  2. Boldine

Boldine 

Cat. No.: HY-N6973
Handling Instructions

Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis.

For research use only. We do not sell to patients.

Boldine Chemical Structure

Boldine Chemical Structure

CAS No. : 476-70-0

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Description

Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis[1].

IC50 & Target

OPG/RANKL/RANK[1]

Molecular Weight

327.37

Formula

C₁₉H₂₁NO₄

CAS No.

476-70-0

SMILES

OC1=C(OC)C2=C3C(CCN(C)[[email protected]@]3([H])CC4=CC(O)=C(OC)C=C24)=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Boldine
Cat. No.:
HY-N6973
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