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Results for "

amide activator

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FAAH (1) ADC Linker (5) Akt (1) Amyloid-β (2) Angiotensin Receptor (1) Antibiotic (1) Apoptosis (2) Autophagy (1) Bacterial (7) Beta-lactamase (1) Biochemical Assay Reagents (96) CGRP Receptor (1) Dihydroorotate Dehydrogenase (2) DNA Methyltransferase (4) DNA/RNA Synthesis (1) Drug Derivative (1) Drug Intermediate (1) Endogenous Metabolite (2) Ephrin Receptor (1) ERK (2) Ferroptosis (2) Fluorescent Dye (12) Formyl Peptide Receptor (FPR) (2) G2A (GPR132) (1) Glutathione Peroxidase (2) Heme Oxygenase (HO) (2) IFNAR (1) Insecticide (2) Integrin (1) Interleukin Related (1) Isotope-Labeled Compounds (1) Keap1-Nrf2 (2) Liposome (3) Melanocortin Receptor (1) MMP (1) NF-κB (5) PAI-1 (2) Parasite (1) PKA (1) Potassium Channel (7) PPAR (2) PROTAC Linkers (19) Protease Activated Receptor (PAR) (8) Proton Pump (2) Radionuclide-Drug Conjugates (RDCs) (1) Reactive Oxygen Species (ROS) (1) Reference Standards (4) Sodium Channel (1) Thrombin (3) Toll-like Receptor (TLR) (2) Trk Receptor (1) TRP Channel (3) γ-Glutamyl Transferase (GGT) (1)
By Research Areas:	Cancer (34) Cardiovascular Disease (7) Endocrinology (1) Infection (9) Inflammation/Immunology (14) Metabolic Disease (5) Neurological Disease (11)
Click Chemistry:	DBCO (5) Azide (2) Tetrazine (1)
Oligonucleotides:	Pegylated Lipids (2) Cationic Lipids (1)

174

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

GMP Molecules

Targets Recommended: FAAH

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108913

Nitrocefin 2 Publications Verification	Beta-lactamase Antibiotic Bacterial	Infection
Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic β-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .

HY-121389

Hexadecanamide Palmitamide	Bacterial NF-κB PPAR	Infection Inflammation/Immunology
Hexadecanamide (Palmitamide) is a fatty acid amide that has orally active anti-allergic, antioxidant, and neuroprotective effects. Hexadecanamide exerts protective effects in Staphylococcus aureus- and SARA-induced mastitis. Hexadecanamide suppresses S. aureus-induced activation of the NF-κB pathway and improves blood-milk barrier integrity. Hexadecanamide activates PPARα. Hexadecanamide enhances sperm motility in vitro. Hexadecanamide can be studied in research for mastitis and asthenozoospermia .

HY-P4744

LL-37 amide 2 Publications Verification	Formyl Peptide Receptor (FPR) Bacterial	Infection Cancer
LL-37 amide is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED₉₉=8.5-8.7 μg/mL). LL-37 amide exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .

HY-P1309

PAR-4 Agonist Peptide, amide 2 Publications Verification PAR-4-AP; AY-NH2	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.

HY-P0283

Protease-Activated Receptor-2, amide 2 Publications Verification	Protease Activated Receptor (PAR)	Cancer
Protease-Activated Receptor-2, amide (SLIGKV-NH₂) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.

HY-P1314

2-Furoyl-LIGRLO-amide 2 Publications Verification	Protease Activated Receptor (PAR)	Inflammation/Immunology
2-Furoyl-LIGRLO-amide is a potent and selective *proteinase-activated* receptor 2 (PAR2) agonist with a pD₂** value of 7.0 ..

HY-Y0973

BOP hexafluorophosphate	Biochemical Assay Reagents Drug Intermediate	Others
BOP hexafluorophosphate is a phosphonium-type condensing agent. BOP hexafluorophosphate activates the carboxylic acid component to form a highly reactive O-benzotriazole ester (active ester) intermediate, which then reacts with the amino component to form an amide bond (peptide bond). BOP hexafluorophosphate is applicable to solid-phase polypeptide synthesis and nucleoside modification .

HY-121833

Gambogic amide	Trk Receptor Akt ERK	Neurological Disease Cancer
Gambogic amide is a potent and selective agonist of TrkA and also induces its tyrosine phosphorylation and activation of downstream signaling, including Akt and MAPK. Gambogic amide specifically interacts with the cytoplasmic juxtamembrane domain of the TrkA receptor and triggers its dimerization, leading to activation. Gambogic amide has neuroprotective activity preventing glutamate-induced neuronal cell death. Gambogic amide has improved efficacy in a transient middle cerebral artery occlusion model of stroke and could be used to study neurodegenerative diseases and stroke .

HY-D1085

AMCA-X SE	Fluorescent Dye	Others
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .

HY-P1309A

PAR-4 Agonist Peptide, amide TFA 2 Publications Verification PAR-4-AP TFA; AY-NH2 TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 Agonist Peptide, amide TFA (PAR-4-AP TFA; AY-NH2 TFA) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist .

HY-P4744A

LL-37 amide TFA 2 Publications Verification	Formyl Peptide Receptor (FPR) Bacterial	Infection Cancer
LL-37 amide TFA is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED₉₉=8.5-8.7 μg/mL). LL-37 amide TFA exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide TFA possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .

HY-P1531

γ-1-Melanocyte Stimulating Hormone (MSH), amide	Melanocortin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology
γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na ⁺) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

HY-W243460

EDTA copper(II) disodium salt, 97%	Biochemical Assay Reagents	Others
EDTA copper (II) disodium salt, 97% is a negatively charged copper (II)-ethylenediaminetetraacetic acid chelate and also an adsorption substrate. EDTA copper (II) disodium salt, 97% forms amide bonds with chitosan amino groups in weakly acidic (pH 3-5) solutions, while it forms the CuEDTA (OH) ³⁻ hydroxyl complex in strongly alkaline (pH > 12) solutions. EDTA copper (II) disodium salt, 97% can be adsorbed onto granular activated carbon, with electrostatic interactions dominating its pH-dependent adsorption behavior. EDTA copper (II) disodium salt, 97% can be used to eliminate the inhibition of enzyme-catalyzed reactions caused by trace heavy metals .

HY-P4004

PAR-4 (1-6) amide (human)	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation .

HY-D2751

BP Fluor 488 cadaverine	Fluorescent Dye	Others
BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.

HY-W717743

DOTAM-mono-acid	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
DOTAM-mono-acid is a chelator with DOTAM as its core. DOTAM-mono-acid contains a carboxylic acid group that can be activated to form an amide bond with the N-terminus of a peptide. DOTAM-mono-acid can form peptide conjugates for radiometal labeling .

HY-W105744

10-Aminodecanoic acid	PROTAC Linkers	Cancer
10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.

HY-W440706

Cholesterol-PEG2000-alcohol	Liposome	Cancer
Cholesterol-PEG2000-alcohol is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.

HY-W1048525

8-Arm PEG5000-NH2 8-Arm PEG5000-Amine	Biochemical Assay Reagents	Others
8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-155765

Anti-inflammatory agent 51	NF-κB	Inflammation/Immunology
Anti-inflammatory agent 51 (compound 11d) is an amide/sulfonamide derivative with anti-inflammatory activities. Anti-inflammatory agent 51 inhibits NF-κB activation, has the potential for acute lung injury and ulcerative colitis research .

HY-W105727

9-Aminononanoic acid	PROTAC Linkers	Cancer
9-Aminononanoic acid can be used as a PROTAC linker and other conjugation in the synthesis of PROTACs. 9-Aminononanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.

HY-P2212

(Asn1,Val5)-Angiotensin II	Angiotensin Receptor	Inflammation/Immunology
Angiotensin amide ((Asn1,Val5)-Angiotensin II) is a potent vasoconstrictor. Angiotensin amide is a derivative of angiotensin II. Angiotensin amide can be used as a cardiac activator .

HY-133053

HO-PEG8-CH2CH2COOH Hydroxy-PEG8-acid	Biochemical Assay Reagents	Others
HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG derivative containing a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators to form a stable amide bond .

HY-130695

N-(Amino-PEG5)-N-bis(PEG4-acid)	ADC Linker	Cancer
N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG derivative containing an amino group with two terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters. The terminal carboxylic acids can react with primary amine groups in the presence of activators to form a stable amide bond. N-(Amino-PEG5)-N-bis(PEG4-acid) can be useful in the development of antibody drug conjugates (ADCs) .

HY-P0249A

Phe-Met-Arg-Phe amide trifluoroacetate	Potassium Channel	Neurological Disease
Phe-Met-Arg-Phe amide trifluoroacetate is an activator of K ⁺ current, with ED₅₀ of 23 nM in the peptidergic caudodorsal neurons.

HY-105069A

Rusalatide acetate TP508 amide acetate	Thrombin	Metabolic Disease Inflammation/Immunology
Rusalatide acetate (TP508 amide acetate), a regenerative peptide, mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity .

HY-P1314A

2-Furoyl-LIGRLO-amide TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
2-Furoyl-LIGRLO-amide TFA is a potent and selective *proteinase-activated* receptor 2 (PAR2) agonist with a pD₂** value of 7.0 ..

HY-133883

Cyanine7.5 amine	Fluorescent Dye	Others
Cyanine7.5 amine is a near-infrared Cy7.5-based dye and also a substrate for amide bond coupling (Ex/Em = 788 nm/808 nm). Cyanine7.5 amine contains a free amino group and can be used for coupling with activated carboxylic acid derivatives .

HY-W510032

9-Ethoxy-9-oxononanoic acid Monoethyl nonanedioate; Ethyl hydrogen azelaate	Biochemical Assay Reagents	Infection
9-Ethoxy-9-oxononanoic acid is a C-11 fatty acid that has an ethyl ester group at the end of the saturated tail. The carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Azelaic Acid Monoethyl Ester has antifungal activity against Cladosporium herbarum.

HY-P3785

PKI(5-22)amide	PKA	Neurological Disease
PKI(5-22)amide is the active inhibitory fragment of the inhibitor of the cyclic AMP-dependent protein kinase (PKA). PKI(5-22)amide inhibits PKA activation, but fails to attenuate homologous desensitization of CRF1 receptors .

HY-P5764

TRAP-14 amide	Protease Activated Receptor (PAR) Integrin MMP	Cardiovascular Disease
TRAP-14 amide, a proteinase activated receptor (PAR)-activating peptide, is a PAR agonist with an EC₅₀ of 24 μM. TRAP-14 amide significantly induces platelet aggregation through ADP- and MMP-2-dependent pathways with Aspirin (HY-14654)-insensitivity. TRAP-14 amide also effectively increases glycoprotein (GP) Ib and GPIIb/IIIa surface expression and ADP release .

HY-P4451

TRAP-5 amide	Protease Activated Receptor (PAR)	Others
TRAP-5 amide is a protease-activated receptor 1 (PAR 1) agonist peptide .

HY-P0249

Phe-Met-Arg-Phe, amide	Potassium Channel	Neurological Disease
Phe-Met-Arg-Phe, amide dose dependently (ED₅₀=23 nM) activates a K ⁺ current in the peptidergic caudodorsal neurons.

HY-P0249B

Phe-Met-Arg-Phe, amide acetate	Potassium Channel	Neurological Disease
Phe-Met-Arg-Phe, amide acetate dose dependently (ED₅₀=23 nM) activates a K ⁺ current in the peptidergic caudodorsal neurons .

HY-D2764

Difluorocarboxyfluorescein cadaverine, 5-isomer	Fluorescent Dye	Others
Difluorocarboxyfluorescein cadaverine, 5-isomer is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.

HY-155070

SRE-II	DNA/RNA Synthesis Apoptosis	Cancer
SRE-II, an amide derivative, is an activatable photosensitizer for photodynamic cancer research with decreased fluorescence and photosensitizing capabilities. SRE-II can be further converted into the active photosensitizer SDU Red via carboxylesterase-catalyzed amide bond cleavage. SRE-II induces DNA damage and cell apoptosis in the presence of light. SRE-II can act as a promising theranostic agent for triple-negative breast cancer .

HY-W800682

Bis-sulfone-PEG4-acid	Biochemical Assay Reagents	Others
Bis-Sulfone-PEG4-acid is a reagent with a sulfone and an acid. The sulfone group can be conjugated with thiol groups of proteins. The terminal acid reacts with primary amines with the help of activators (EDC or HATU) to from stable amide bonds.

HY-23629

16-Aminohexadecanoic acid	PROTAC Linkers	Cancer
16-Aminohexadecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 16-Aminohexadecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.

HY-W401143

15-Aminopentadecanoic acid	PROTAC Linkers	Cancer
15-Aminopentadecanoic Acid can be used as a PROTAC linker in the synthesis of PROTACs. 15-Aminopentadecanoic Acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.

HY-W800825

Octadecanedioic acid mono-L-carnitine ester	Liposome	Cancer
Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.

HY-176726

ZnPc-amide-PEG3-C2-NH2	Reactive Oxygen Species (ROS)	Cancer
ZnPc-amide-PEG3-C2-NH2 is a photosensitizer-linker conjugate which consists of ZnPcPs (HY-176725) and a linker (HY-W040165). ZnPc-amide-PEG3-C2-NH2 can be used to synthesize the photo-activated BRD4 degrader pZnPc-O3-JQ1 (HY-176724) .

HY-W190752

m-PEG13-acid	Biochemical Assay Reagents	Others
m-PEG13-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

HY-W800676

DBCO-N-bis(PEG4-acid)	Biochemical Assay Reagents	Others
DBCO-N-bis(PEG4-acid) is a branched click chemistry reagent. The DBCO group enables copper-free Click Chemistry reactions. carboxylic acid groups allows for reactions with primary amine groups using activators such as EDC or HATU to form a stable amide bond.

HY-D1366A

Sulfo-Cyanine5.5 carboxylic acid potassium	Fluorescent Dye	Others
Sulfo-Cyanine5.5 carboxylic acid potassium is a fluorescent dye with excitation/emission wavelengths at 673/707 nm. The introduction of the sulfite group enhances the hydrophilic properties of the compound. The terminal carboxylic acid can react with primary amine groups in the presence of activators such as EDC and HATU, to form stable amide bonds.

HY-W190951

3-((2-(2,2,2-Trifluoroacetamido)ethyl)disulfanyl)propanoic acid	Biochemical Assay Reagents	Others
3-((2-(2,2,2-Trifluoroacetamido)ethyl)disulfanyl)propanoic acid is a cleavable linker containing a carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The disulfide bond can be cleaved via reduction reactions.

HY-W143822

6-(Tritylthio)hexanoic acid	Biochemical Assay Reagents	Others
6-(Tritylthio)hexanoic acid is a linker with a Tst group and a terminal carboxylic acid. The Tst group can be deprotected under acidic conditions to obtain the free thiol which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

HY-161272

Nav1.8-IN-6	Sodium Channel	Neurological Disease
Nav1.8-IN-6 (Compound 2j) is a novel pyridinone amide Nav1.8 channel inhibitor. The IC₅₀ values in the resting state and semi-activated state are 513.33 and 471.81 nM, respectively. Nav1.8-IN-6 has analgesic activity .

HY-W800683

4-Azide-TFP-amide-SS-Sulfo-NHS	Biochemical Assay Reagents	Others
4-Azide-TFP-Amide-SS-Sulfo-NHS consists of an aryl azide, a cleavable disulfide bond, and an NHS ester. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The NHS ester reacts with amines. The disulfide bond can be cleaved by reducing agents.

HY-140895B

Biotin-PEG10000-Amine Biotin-PEG10000-NH2	Biochemical Assay Reagents	Others
Biotin-PEG10000-Amine (Biotin-PEG10000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-140895D

Biotin-PEG40000-Amine Biotin-PEG40000-NH2	Biochemical Assay Reagents	Others
Biotin-PEG40000-Amine (Biotin-PEG40000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

Cat. No.	Product Name	Type

HY-D1085

AMCA-X SE	Fluorescent Dyes
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .

HY-D2751

BP Fluor 488 cadaverine	Fluorescent Dyes
BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.

HY-133883

Cyanine7.5 amine	Fluorescent Dyes
Cyanine7.5 amine is a near-infrared Cy7.5-based dye and also a substrate for amide bond coupling (Ex/Em = 788 nm/808 nm). Cyanine7.5 amine contains a free amino group and can be used for coupling with activated carboxylic acid derivatives .

HY-D2772

5-TAMRA Cadaverine

Fluorescent Dyes

5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.

HY-W1048843AGL

4-Arm PEG5000-NH2 (GMP Like)

4-Arm PEG5000-amine (GMP Like)

Fluorescent Dyes

4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-D2764

Difluorocarboxyfluorescein cadaverine, 5-isomer	Fluorescent Dyes
Difluorocarboxyfluorescein cadaverine, 5-isomer is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.

HY-D1366A

Sulfo-Cyanine5.5 carboxylic acid potassium	Fluorescent Dyes
Sulfo-Cyanine5.5 carboxylic acid potassium is a fluorescent dye with excitation/emission wavelengths at 673/707 nm. The introduction of the sulfite group enhances the hydrophilic properties of the compound. The terminal carboxylic acid can react with primary amine groups in the presence of activators such as EDC and HATU, to form stable amide bonds.

HY-D2895A

RB-PEG600-NH2 Rhodamine B-PEG600-NH2	Fluorescent Dyes
RB-PEG600-NH2 (Rhodamine B-PEG600-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895H

RB-PEG10000-NH2 Rhodamine B-PEG10000-NH2	Fluorescent Dyes
RB-PEG10000-NH2 (Rhodamine B-PEG10000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895D

RB-PEG3400-NH2 Rhodamine B-PEG3400-NH2	Fluorescent Dyes
RB-PEG3400-NH2 (Rhodamine B-PEG3400-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895B

RB-PEG1000-NH2 Rhodamine B-PEG1000-NH2	Fluorescent Dyes
RB-PEG1000-NH2 (Rhodamine B-PEG1000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895

RB-PEG400-NH2 Rhodamine B-PEG400-NH2	Fluorescent Dyes
RB-PEG400-NH2 (Rhodamine B-PEG400-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2765

BP Fluor 405 cadaverine

Fluorescent Dyes

BP Fluor 405 Cadaverine is a carbonyl-reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Another common application for BP Fluor 405 Cadaverine is cell fixing by treatment with formaldehyde or glutaraldehyde. BP Fluor 405 is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode.

HY-D2895E

RB-PEG5000-NH2 Rhodamine B-PEG5000-NH2	Fluorescent Dyes
RB-PEG5000-NH2 (Rhodamine B-PEG5000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895C

RB-PEG2000-NH2 Rhodamine B-PEG2000-NH2	Fluorescent Dyes
RB-PEG2000-NH2 (Rhodamine B-PEG2000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-W1048843AG

4-Arm PEG5000-NH2

4-Arm PEG5000-amine

Fluorescent Dyes

4-Arm PEG5000-NH2 (GMP) (4-Arm PEG5000-amine (GMP)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

Cat. No.	Product Name	Type

HY-Y0623

N-Hydroxysuccinimide

5+ Cited Publications

HOSu; 1-Hydroxy-2,5-pyrrolidinedione

Biochemical Assay Reagents

N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .

HY-Y1168

DMTMM

2 Publications Verification

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

Biochemical Assay Reagents

DMTMM (4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methylmorpholinium chloride) is a coupling agent. DMTMM can activate carboxyl groups and promote the formation of amide bonds. DMTMM plays an important role in promoting the chemical modification of biomacromolecules such as polysaccharides and proteins. DMTMM can be used for research of tissue engineering, breast cancer, corneal regeneration, and biomaterials .

HY-Y0973

BOP hexafluorophosphate	Biochemical Assay Reagents
BOP hexafluorophosphate is a phosphonium-type condensing agent. BOP hexafluorophosphate activates the carboxylic acid component to form a highly reactive O-benzotriazole ester (active ester) intermediate, which then reacts with the amino component to form an amide bond (peptide bond). BOP hexafluorophosphate is applicable to solid-phase polypeptide synthesis and nucleoside modification .

HY-112624K

Dextran T5 (MW 5,000)

Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)

Biochemical Assay Reagents

Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-W717743

DOTAM-mono-acid	Biochemical Assay Reagents
DOTAM-mono-acid is a chelator with DOTAM as its core. DOTAM-mono-acid contains a carboxylic acid group that can be activated to form an amide bond with the N-terminus of a peptide. DOTAM-mono-acid can form peptide conjugates for radiometal labeling .

HY-W1048525

8-Arm PEG5000-NH2 8-Arm PEG5000-Amine	Biochemical Assay Reagents
8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843A

4-Arm PEG5000-NH2 4-Arm PEG5000-amine	Biochemical Assay Reagents
4-Arm PEG5000-NH2 (4-Arm PEG5000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843B

4-Arm PEG10000-NH2 4-Arm PEG10000-amine	Biochemical Assay Reagents
4-Arm PEG10000-NH2 (4-Arm PEG10000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048519A

4-Arm PEG10000-NH2 hydrochloride 4-Arm PEG10000-amine HCL salt	Biochemical Assay Reagents
4-Arm PEG10000-NH2 (4-Arm PEG100000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843AGL

4-Arm PEG5000-NH2 (GMP Like)

4-Arm PEG5000-amine (GMP Like)

Biochemical Assay Reagents

HY-140895B

Biotin-PEG10000-Amine Biotin-PEG10000-NH2	Biochemical Assay Reagents
Biotin-PEG10000-Amine (Biotin-PEG10000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-140895D

Biotin-PEG40000-Amine Biotin-PEG40000-NH2	Biochemical Assay Reagents
Biotin-PEG40000-Amine (Biotin-PEG40000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-140895C

Biotin-PEG20000-Amine Biotin-PEG20000-NH2	Biochemical Assay Reagents
Biotin-PEG20000-Amine (Biotin-PEG20000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-W1048525B

8-Arm PEG40000-NH2 8-Arm PEG40000-Amine	Biochemical Assay Reagents
8-Arm PEG40000-NH2 (8-Arm PEG40000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048526

8-Arm PEG5000-NH2 HCL 8-Arm PEG5000-amine HCL salt	Biochemical Assay Reagents
8-Arm PEG5000-NH2 (8-Arm PEG5000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048526A

8-Arm PEG20000-NH2 HCL 8-Arm PEG20000-amine HCL salt	Biochemical Assay Reagents
8-Arm PEG20000-NH2 (8-Arm PEG20000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048519B

4-Arm PEG20000-NH2 hydrochloride 4-Arm PEG20000-amine HCL salt	Biochemical Assay Reagents
4-Arm PEG20000-NH2 (4-Arm PEG20000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048519

4-Arm PEG5000-NH2 hydrochloride 4-Arm PEG5000-amine HCL salt	Biochemical Assay Reagents
4-Arm PEG5000-NH2 (4-Arm PEG5000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-155885

mPEG40000-amine mPEG40000-NH2	Biochemical Assay Reagents
mPEG40000-amine (mPEG40000-NH2) is a monofunctional polyPEG with a terminal amine. The coupling between NHS ester and amine produces a stable amide bond. The amine moieties is also reactive with carboxyl in the presence of activating agent .

HY-200288B

DMG-PEG3400-COOH	Biochemical Assay Reagents
DMG-PEG3400-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052117A

DMPE-PEG3400-COOH	Biochemical Assay Reagents
DMPE-PEG3400-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052873C

DPPE-PEG1000-COOH	Biochemical Assay Reagents
DPPE-PEG1000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052117

DMPE-PEG2000-COOH	Biochemical Assay Reagents
DMPE-PEG2000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-183173B

DSG-PEG3400-COOH	Biochemical Assay Reagents
DSG-PEG3400-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-183173

DSG-PEG1000-COOH	Biochemical Assay Reagents
DSG-PEG1000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052873D

DPPE-PEG10000-COOH	Biochemical Assay Reagents
DPPE-PEG10000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-200288

DMG-PEG2000-COOH	Biochemical Assay Reagents
DMG-PEG2000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-183173A

DSG-PEG2000-COOH	Biochemical Assay Reagents
DSG-PEG2000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-200288A

DMG-PEG1000-COOH	Biochemical Assay Reagents
DMG-PEG1000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052873

DPPE-PEG2000-COOH	Biochemical Assay Reagents
DPPE-PEG2000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052117D

DMPE-PEG10000-COOH	Biochemical Assay Reagents
DMPE-PEG1000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-183173D

DSG-PEG10000-COOH	Biochemical Assay Reagents
DSG-PEG10000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-200288D

DMG-PEG10000-COOH	Biochemical Assay Reagents
DMG-PEG10000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052873B

DPPE-PEG5000-COOH	Biochemical Assay Reagents
DPPE-PEG5000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052873A

DPPE-PEG3400-COOH	Biochemical Assay Reagents
DPPE-PEG3400-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052117C

DMPE-PEG1000-COOH	Biochemical Assay Reagents
DMPE-PEG1000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-183173C

DSG-PEG5000-COOH	Biochemical Assay Reagents
DSG-PEG5000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-200288C

DMG-PEG5000-COOH	Biochemical Assay Reagents
DMG-PEG5000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W1052117B

DMPE-PEG5000-COOH	Biochemical Assay Reagents
DMPE-PEG5000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.

HY-W414754

2,5-Dioxopyrrolidin-1-yl methyl phthalate	Biochemical Assay Reagents
2,5-Dioxopyrrolidin-1-yl methyl phthalate is a cross-linking agent used for modification of proteins and peptides. 2,5-Dioxopyrrolidin-1-yl methyl phthalate is a reagent for introducing succinimide-activated esters that react with primary amines in proteins and peptides to form stable amide bonds.

HY-140895A

Biotin-PEG5000-Amine Biotin-PEG5000-NH2	Biochemical Assay Reagents
Biotin-PEG5000-Amine (Biotin-PEG5000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-W1048526C

8-Arm PEG10000-NH2 HCL 8-Arm PEG10000-amine HCL salt	Biochemical Assay Reagents
8-Arm PEG10000-NH2 (8-Arm PEG10000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048525C

8-Arm PEG10000-NH2 8-Arm PEG10000-Amine	Biochemical Assay Reagents
8-Arm PEG10000-NH2 (8-Arm PEG10000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048526B

8-Arm PEG40000-NH2 HCL 8-Arm PEG40000-amine HCL salt	Biochemical Assay Reagents
8-Arm PEG40000-NH2 (8-Arm PEG40000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048525A

8-Arm PEG20000-NH2 8-Arm PEG20000-Amine	Biochemical Assay Reagents
8-Arm PEG20000-NH2 (8-Arm PEG20000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843C

4-Arm PEG20000-NH2 4-Arm PEG20000-amine	Biochemical Assay Reagents
4-Arm PEG20000-NH2 (4-Arm PEG20000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048519C

4-Arm PEG40000-NH2 hydrochloride 4-Arm PEG40000-amine HCL salt	Biochemical Assay Reagents
4-Arm PEG40000-NH2 (4-Arm PEG40000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843D

4-Arm PEG40000-NH2 4-Arm PEG40000-amine	Biochemical Assay Reagents
4-Arm PEG40000-NH2 (4-Arm PEG40000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-183133B

C16-PEG5000-COOH	Biochemical Assay Reagents
C16-PEG5000-COOH is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C16-PEG5000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.

HY-183168B

C18-PEG5000-COOH	Biochemical Assay Reagents
C18-PEG5000-COOH is a conjugate composed of an octadecyl group (C18 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C18-PEG5000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.

Cat. No.	Product Name	Target	Research Area

HY-P4744

LL-37 amide 2 Publications Verification	Formyl Peptide Receptor (FPR) Bacterial	Infection Cancer
LL-37 amide is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED₉₉=8.5-8.7 μg/mL). LL-37 amide exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .

HY-P1309

PAR-4 Agonist Peptide, amide 2 Publications Verification PAR-4-AP; AY-NH2	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.

HY-P0283

Protease-Activated Receptor-2, amide 2 Publications Verification	Protease Activated Receptor (PAR)	Cancer
Protease-Activated Receptor-2, amide (SLIGKV-NH₂) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.

HY-P1314

2-Furoyl-LIGRLO-amide 2 Publications Verification	Protease Activated Receptor (PAR)	Inflammation/Immunology
2-Furoyl-LIGRLO-amide is a potent and selective *proteinase-activated* receptor 2 (PAR2) agonist with a pD₂** value of 7.0 ..

HY-P1309A

PAR-4 Agonist Peptide, amide TFA 2 Publications Verification PAR-4-AP TFA; AY-NH2 TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 Agonist Peptide, amide TFA (PAR-4-AP TFA; AY-NH2 TFA) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist .

HY-P4744A

LL-37 amide TFA 2 Publications Verification	Formyl Peptide Receptor (FPR) Bacterial	Infection Cancer
LL-37 amide TFA is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED₉₉=8.5-8.7 μg/mL). LL-37 amide TFA exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide TFA possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing .

HY-P1531

γ-1-Melanocyte Stimulating Hormone (MSH), amide	Melanocortin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology
γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na ⁺) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

HY-P4004

PAR-4 (1-6) amide (human)	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation .

HY-P2212

(Asn1,Val5)-Angiotensin II	Angiotensin Receptor	Inflammation/Immunology
Angiotensin amide ((Asn1,Val5)-Angiotensin II) is a potent vasoconstrictor. Angiotensin amide is a derivative of angiotensin II. Angiotensin amide can be used as a cardiac activator .

HY-P0249A

Phe-Met-Arg-Phe amide trifluoroacetate	Potassium Channel	Neurological Disease
Phe-Met-Arg-Phe amide trifluoroacetate is an activator of K ⁺ current, with ED₅₀ of 23 nM in the peptidergic caudodorsal neurons.

HY-105069A

Rusalatide acetate TP508 amide acetate	Thrombin	Metabolic Disease Inflammation/Immunology
Rusalatide acetate (TP508 amide acetate), a regenerative peptide, mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity .

HY-P1314A

2-Furoyl-LIGRLO-amide TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
2-Furoyl-LIGRLO-amide TFA is a potent and selective *proteinase-activated* receptor 2 (PAR2) agonist with a pD₂** value of 7.0 ..

HY-P4863

Biotinyl-Amylin (human)	CGRP Receptor	Neurological Disease Metabolic Disease
Biotinyl-Amylin (human) is a biotin-labeled derivative of Amylin, amide, human (HY-P1070). Biotinyl-Amylin (human) acts as a competitive agonist for the Calcitonin Receptor (CTR) and for the Amylin receptors (AMY₁, AMY₂, and AMY₃) formed by the association of CTR with RAMP1/2/3. By mimicking endogenous human amylin, Biotinyl-Amylin (human) binds to and activates CTR and AMY receptors, thereby initiating downstream signaling pathways involving cAMP, CREB, and ERK1/2, while retaining high-affinity receptor binding and activation capabilities. Biotinyl-Amylin (human) is primarily utilized in studies investigating the metabolic regulatory mechanisms underlying obesity and diabetes; it is also applicable to pharmacological research, receptor localization studies, and ligand-binding assays related to Amylin receptors in the context of Alzheimer's disease .

HY-P3785

PKI(5-22)amide	PKA	Neurological Disease
PKI(5-22)amide is the active inhibitory fragment of the inhibitor of the cyclic AMP-dependent protein kinase (PKA). PKI(5-22)amide inhibits PKA activation, but fails to attenuate homologous desensitization of CRF1 receptors .

HY-P5764

TRAP-14 amide	Protease Activated Receptor (PAR) Integrin MMP	Cardiovascular Disease
TRAP-14 amide, a proteinase activated receptor (PAR)-activating peptide, is a PAR agonist with an EC₅₀ of 24 μM. TRAP-14 amide significantly induces platelet aggregation through ADP- and MMP-2-dependent pathways with Aspirin (HY-14654)-insensitivity. TRAP-14 amide also effectively increases glycoprotein (GP) Ib and GPIIb/IIIa surface expression and ADP release .

HY-P4451

TRAP-5 amide	Protease Activated Receptor (PAR)	Others
TRAP-5 amide is a protease-activated receptor 1 (PAR 1) agonist peptide .

HY-P0249

Phe-Met-Arg-Phe, amide	Potassium Channel	Neurological Disease
Phe-Met-Arg-Phe, amide dose dependently (ED₅₀=23 nM) activates a K ⁺ current in the peptidergic caudodorsal neurons.

HY-P0249B

Phe-Met-Arg-Phe, amide acetate	Potassium Channel	Neurological Disease
Phe-Met-Arg-Phe, amide acetate dose dependently (ED₅₀=23 nM) activates a K ⁺ current in the peptidergic caudodorsal neurons .

Cat. No.	Product Name

HY-KD1113

Biotinylated Rapid Labeling Kit

The Biotinylation Rapid Labelling Kit enables biotinylation of proteins. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled within a pH 7-9 solution, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2-8 molecules of biotin. The entire procedure can be completed within two hours.

HY-KD1115

DOTA Rapid Labeling Kit

The DOTA rapid labelling kit enables DOTA labelling of proteins. Based on NHS ester chemistry, NHS ester-activated fluorescent dyes react with primary amines on the antibody/protein to form stable amide bonds at pH 7–9, thereby achieving conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2–8 DOTA molecules. The entire procedure can be completed within 2 hours.

HY-KD1114

Nota Rapid Labeling Kit

The NOTA Rapid Labelling Kit enables NOTA labelling of proteins. Based on NHS ester chemistry, NHS ester-activated fluorescent dyes react with primary amines on the antibody/protein to be labelled in a pH 7-9 solution, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2–8 NOTA molecules. The entire procedure can be completed within two hours.

HY-KD1101

Green Fluorescent Rapid Labeling Kit (FITC）

Green Fluorescent Rapid Labelling Kit (FITC) enables green fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 488/515 nm. Based on NHS-ester chemistry, the NHS-ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of FITC. The entire procedure can be completed within two hours.

HY-KD1106

Deep Red Fluorescent Rapid Labeling Kit (AF647）

Red Fluorescent Rapid Labelling Kit (AF647) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 647/665 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF647. The entire procedure can be completed within two hours.

HY-KD1112

Blue Fluorescent Rapid Labeling Kit (AF350）

TheBlue Fluorescence Rapid Labelling Kit (AF350) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 346/442 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF350. The entire procedure can be completed within two hours.

HY-KD1103

Red Fluorescent Rapid Labeling Kit (CY3）

Red Fluorescent Rapid Labelling Kit (CY3) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 550/570 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, one IgG molecule can bind 2–8 molecules of CY3. The entire experiment can be completed within 2 hours.

HY-KD1107

Deep Red Fluorescent Rapid Labeling Kit (CY5）

Deep Red Fluorescent Rapid Labelling Kit (CY5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 649/667 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2–8 molecules of CY5. The entire experiment can be completed within 2 hours.

HY-KD1111

NIR Red Fluorescent Rapid Labeling Kit (AF750）

Near-infrared Fluorescent Rapid Labelling Kit (AF750) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 750/775 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF750. The entire procedure can be completed within two hours.

HY-KD1102

Green Fluorescent Rapid Labeling Kit (AF488）

Green Fluorescent Rapid Labelling Kit (AF488) enables green fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 480/525 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF488. The entire procedure can be completed within two hours.

HY-KD1105

Red Fluorescent Rapid Labeling Kit (AF594）

Red Fluorescent Rapid Labelling Kit (AF594) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 594/617 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF594. The entire procedure can be completed within two hours.

HY-KD1104

Red Fluorescent Rapid Labeling Kit (AF555）

Red Fluorescent Rapid Labelling Kit (AF555) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 555/565 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds with the target antibody/protein, achieving conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF555. The entire procedure can be completed within two hours.

HY-KD1109

NIR Red Fluorescent Rapid Labeling Kit (CY7）

Near-infrared Fluorescent Rapid Labelling Kit (CY7) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 750/773 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2–8 molecules of CY7. The entire experiment can be completed within 2 hours.

HY-KD1108

Deep Red Fluorescent Rapid Labeling Kit (CY5.5）

Deep Red Fluorescent Rapid Labelling Kit (CY5.5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 678/695 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of CY5.5. The entire procedure can be completed within two hours.

HY-KD1110

NIR Red Fluorescent Rapid Labeling Kit (CY7.5）

The Near-Infrared Fluorescence Rapid Labelling Kit (CY7.5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 788/814 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of CY7.5. The entire procedure can be completed within two hours.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121389

Hexadecanamide Palmitamide	Infection Alkaloids Cannabis sativa L Classification of Application Fields Other Alkaloids Plants Moraceae Inflammation/Immunology Disease Research Fields Source Classification	Bacterial NF-κB PPAR
Hexadecanamide (Palmitamide) is a fatty acid amide that has orally active anti-allergic, antioxidant, and neuroprotective effects. Hexadecanamide exerts protective effects in Staphylococcus aureus- and SARA-induced mastitis. Hexadecanamide suppresses S. aureus-induced activation of the NF-κB pathway and improves blood-milk barrier integrity. Hexadecanamide activates PPARα. Hexadecanamide enhances sperm motility in vitro. Hexadecanamide can be studied in research for mastitis and asthenozoospermia .

HY-N3097

Pellitorine	Alkaloids Classification of Application Fields Other Alkaloids Piperaceae Plants Disease Research Fields Piper nigrum Linn. Biological Pesticide Research Source Classification Cancer Agricultural Research	TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB ERK Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial
Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria .

HY-121389R

Hexadecanamide (Standard) Palmitamide (Standard)	Structural Classification Alkaloids Cannabis sativa L Other Alkaloids Plants Moraceae Source Classification	Bacterial NF-κB PPAR Reference Standards
Hexadecanamide (Standard) is the analytical standard of Hexadecanamide. This product is intended for research and analytical applications. Hexadecanamide (Palmitamide) is a fatty acid amide that has orally active anti-allergic, antioxidant, and neuroprotective effects. Hexadecanamide exerts protective effects in Staphylococcus aureus- and SARA-induced mastitis. Hexadecanamide suppresses S. aureus-induced activation of the NF-κB pathway and improves blood-milk barrier integrity. Hexadecanamide activates PPARα. Hexadecanamide enhances sperm motility in vitro. Hexadecanamide can be studied in research for mastitis and asthenozoospermia .

HY-W016586R

Acivicin (Standard) AT-125 (Standard); U-42126 (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Reference Standards Parasite γ-Glutamyl Transferase (GGT)
Articaine (Standard) is the analytical standard of Articaine. This product is intended for research and analytical applications. Articaine (Hoe-045 free base) is an amide agent that can suppress or relieve pain. containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-κB activation and the NLRP3 inflammasome pathway .

HY-N3097R

Pellitorine (Standard)	Alkaloids Other Alkaloids Piperaceae Plants Piper nigrum Linn. Source Classification	Reference Standards TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial
Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.

Cat. No.	Product Name	Chemical Structure

HY-A0084AS

Procainamide-d4

Procainamide-d₄ (Procaine amide-d₄) is the deuterium labeled Procainamide (HY-A0084A). Procainamide (Procaine amide) is a specific and potent inhibitor of DNA methyltransferase 1 (DNMT1), which reactivates the expression of tumor suppressor factors by demethylating tumor suppressor genes. Procainamide induces vacuolization in various cell types and reduces cell proliferation and migration. Procainamide relaxes airway smooth muscle by activating potassium channels. Procainamide can be used in cancer and arrhythmia research .

Cat. No.	Product Name		Classification

HY-151647

3-Azidopropanoic acid-PFP ester		Azide
3-Azidopropanoic acid-PFP ester is an azidopropanoic acid linker that contains an activated PFP ester. The azide group can undergo copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to form triazole linkages. The activated PFP ester can react with amine groups to form stable amide bonds . 3-Azidopropanoic acid-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151821

Sulfo DBCO-PEG3-acid		DBCO
Sulfo DBCO-PEG3-acid is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .

HY-151820

DBCO-PEG24-acid		DBCO
DBCO-PEG24-acid is a click chemistry reagent. DBCO-PEG24-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .

HY-148840

Sulfo DBCO-PEG3-NHS ester		DBCO
Sulfo DBCO-PEG3-NHS ester is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-NHS ester is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .

HY-W800676

DBCO-N-bis(PEG4-acid)		DBCO
DBCO-N-bis(PEG4-acid) is a branched click chemistry reagent. The DBCO group enables copper-free Click Chemistry reactions. carboxylic acid groups allows for reactions with primary amine groups using activators such as EDC or HATU to form a stable amide bond.

HY-148840A

Sulfo DBCO-PEG3-NHS ester TEA		DBCO
Sulfo DBCO-PEG3-NHS ester TEA is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-NHS ester (TEA) is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .

HY-151833

Methyltetrazine-amido-N-bis(PEG4-acid)		Tetrazine
Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only . Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-W800653

N-(Azido-PEG3)-NH-PEG3-t-butyl ester		Azide
N-(Azido-PEG3)-NH-PEG3-t-butyl ester is a click chemistry reagent with a terminal azide group and secondary amine NH group. NH group is reactive with NHS ester, The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The azide group can participate in Click Chemistry.

Cat. No.	Product Name		Classification

HY-W440706

Cholesterol-PEG2000-alcohol		Pegylated Lipids
Cholesterol-PEG2000-alcohol is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.

HY-W800825

Octadecanedioic acid mono-L-carnitine ester		Cationic Lipids
Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.

HY-W440954

Stearic acid-PEG2000-CH2CO2H		Pegylated Lipids
Stearic acid-PEG2000-CH2CO2H is a heterobifunctional polyPEG with 18-carbon aliphatic chain and carboxyl. The polymer has stearic acid as the hydrophobic tail and PEG as the hydrophilic chain, therefore it forms micelles in water. Carboxyl can react with amine in the presence of activator, such as HATU/EDC to generate a stable amide bond. Reagent grade, for research use only.

Targets Recommended: FAAH

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W1048843AG

4-Arm PEG5000-NH2 4-Arm PEG5000-amine	Biochemical Assay Reagents	Others
4-Arm PEG5000-NH2 (GMP) (4-Arm PEG5000-amine (GMP)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843AGL

4-Arm PEG5000-NH2 (GMP Like) 4-Arm PEG5000-amine (GMP Like)	Biochemical Assay Reagents	Others
4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

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