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Results for "

antiatherosclerosis

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

8

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1372A
    Fangchinoline
    5+ Cited Publications

    		 HIV FAK Apoptosis Autophagy Infection Cancer
    Fangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing . Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK . Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer .
    Fangchinoline
  • HY-N15574
    Saringosterol

    		LXR Bacterial PPAR Infection Neurological Disease Metabolic Disease Inflammation/Immunology
    Saringosterol is an orally active steroid found in Sargassum muticum. Saringosterol is a LXR agonist. Saringosterol can lower cholesterol levels and inhibit the mRNA and protein expression of peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT enhancer-binding protein α (C/EBPα). Saringosterol has anti-obesity, anti-atherosclerosis, anti-Mycobacterium tuberculosis and anti-depressant activities .
    Saringosterol
  • HY-N3297
    Meranzin hydrate
    1 Publications Verification

    		 Others Cardiovascular Disease Neurological Disease
    Meranzin hydrate, an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), possess anti-depression and anti-atherosclerosis effects .
    Meranzin hydrate
  • HY-142019
    Tanshinol borneol ester

    		Akt AMPK Cardiovascular Disease
    Tanshinol borneol ester, an angiogenesis stimulator, promoted multiple key steps of angiogenesis through Akt and MAPK signalling pathways. Tanshinol borneol ester has anti-ischemic and anti-atherosclerosis activities .
    Tanshinol borneol ester
  • HY-W674245
    10-Hydroxyhexadecanoic acid

    		ATP-binding cassette (ABC) transporters Cardiovascular Disease
    10-Hydroxyhexadecanoic acid is a hydroxy fatty acid found in Camembert cheese. 10-Hydroxyhexadecanoic acid can promote cholesterol efflux from ABCA1 and ABCG1, preventing the accumulation of excess cholesterol in cells. 10-Hydroxyhexadecanoic acid can be used in anti-atherosclerosis research .
    10-Hydroxyhexadecanoic acid
  • HY-W791754
    Paeonolsilate sodium

    		NF-κB Cardiovascular Disease
    Paeonolsilate (sodium) can inhibit ox-LDL-induced macrophage foam cell formation and inflammation in atherosclerosis. Paeonolsilate (sodium) inhibits NF-κB activation and oxidative stress response induced by ox-LDL. Paeonolsilate (sodium) can be studied in anti-atherosclerosis research .
    Paeonolsilate sodium
  • HY-176043
    PCSK9 autophagic degrader 2

    		ATTECs PCSK9 Cancer
    PCSK9 autophagic degrader 2 (W6) is a PCSK9 targeted autophagosome, with an DC50 of 20.6 nM. PCSK9 autophagic degrader 2 (W6) demonstrates comparable antiatherosclerosis effect and exhibits a KD of 2.5 μM for LC3B (Pink: PCSK9 ligand HY-176044; Blue: LC3B ligand HY-176045; Black: linker HY-141373) .
    PCSK9 autophagic degrader 2
  • HY-N1372AR
    Fangchinoline (Standard)

    		Reference Standards HIV FAK Apoptosis Autophagy Infection Cancer
    Fangchinoline (Standard) is the analytical standard of Fangchinoline. This product is intended for research and analytical applications. Fangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing . Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK . Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer .
    Fangchinoline (Standard)
  • HY-176044
    PCSK9 ligand 2

    		Ligands for Target Protein for PROTAC Cancer
    PCSK9 ligand 2 is a target protein ligand for PROTAC PCSK9 autophagic degrader 2 (HY-176043), which can be used in antiatherosclerosis research .
    PCSK9 ligand 2
  • HY-N3297R
    Meranzin hydrate (Standard)

    		Reference Standards Others Cardiovascular Disease Neurological Disease
    Meranzin (hydrate) (Standard) is the analytical standard of Meranzin (hydrate). This product is intended for research and analytical applications. Meranzin hydrate, an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), possess anti-depression and anti-atherosclerosis effects .
    Meranzin hydrate (Standard)
  • HY-N0712R
    Typhaneoside (Standard)

    		Reference Standards Autophagy Cardiovascular Disease Inflammation/Immunology
    Typhaneoside (Standard) is the analytical standard of Typhaneoside. This product is intended for research and analytical applications. Typhaneoside, extracted from Typha angustifolia L., Typhaneoside can inhibit the excessive autophagy of hypoxia/reoxygenation cells and increase the phosphorylation of Akt and mTOR. Typhaneoside has certain effects on the cardiovascular system, including lowering blood lipid levels, promoting antiatherosclerosis activities, as well as improving immune and coagulation function .
    Typhaneoside (Standard)
  • HY-N19044
    Ilex kudincha extract

    		Others Cardiovascular Disease
    Ilex Kudincha Extracts is derived from the tender leaves of Ilex holly and Ilex kudingcha. Ilex kudincha extract has the effects of lowering blood lipids, increasing myocardial blood supply, and anti-atherosclerosis.
    Ilex kudincha extract

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