11 Results for "

autophagy-enhancer

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "autophagy-enhancer" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N0901
CAS No.: 6877-32-3
Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
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Cat. No.: HY-N8678
CAS No.: 271579-12-5
Thonningianin B is an antioxidant and an autophagy enhancer .
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Cat. No.: HY-117924
CAS No.: 1783800-77-0
Purity:  97.14%
Synonyms: autophagy enhancer-67
Target:  

Autophagy

Research Areas:  

Neurological Disease

AUTEN-67 (Autophagy enhancer-67) is an orally active autophagy enhancer and MTMR14 inhibitor. AUTEN-67 has anti-aging and neuroprotective effects. AUTEN-67 protects neurons from stress-induced cell death. AUTEN-67 also restores nesting behavior in a mice model of Alzheimer disease .
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Cat. No.: HY-W489121
CAS No.: 774192-20-0
Target:  

p62 Autophagy AUTOTACs

Research Areas:  

Cancer

YTK-105 is a p62/ZZ binding domain ligand and Autophagy enhancer. YTK-105 activates p62-dependent selective macroautophagy. YTK-105 serves as an autophagy-targeting ligand (ATL) for synthesizing AUTOTAC degraders .
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Cat. No.: HY-N3741
CAS No.: 18296-45-2
Synonyms: Didrovaltratum
Didrovaltrate (Didrovaltratum) is an L-type calcium channel blocker, ROS scavenger, autophagy enhancer, and lipid accumulation inhibitor. Didrovaltrate blocks L-type calcium currents in a concentration-dependent manner, shifts the current-voltage curve upward, modulates steady-state inactivation kinetics, and inhibits the nuclear translocation of glucocorticoid receptors. Didrovaltrate reduces ROS levels, downregulates the expression of muscle atrophy-related genes, enhances autophagy via lipophagy, and decreases Oleic acid-induced lipid accumulation. Didrovaltrate exhibits cytotoxic activity against cancer cells. Didrovaltrate can be used in research related to skeletal muscle atrophy, non-alcoholic fatty liver disease, breast cancer, lung cancer, gastric cancer, and prostate cancer .
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Cat. No.: HY-125197
CAS No.: 2446154-91-0
Target:  

Autophagy

Research Areas:  

Inflammation/Immunology

BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway. BRD5631 affects several cellular disease phenotypes previously linked to autophagy, including protein aggregation, cell survival, bacterial replication, and inflammatory cytokine production .
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Cat. No.: HY-D2227
CAS No.: 2374274-85-6
IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .
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Cat. No.: HY-101485
CAS No.: 1049780-58-6
Synonyms: autophagy enhancer-99 hydrobromide
Target:  

Phosphatase

Research Areas:  

Neurological Disease

AUTEN-99 (hydrobromide) is a novel inhibitor of the myotubularin phosphatase Jumpy (also called MTMR14). AUTEN-99 (hydrobromide) crosses the blood-brain barrier and exerts potent neuroprotective effects .
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Cat. No.: HY-N4120
CAS No.: 51771-49-4
Valechlorine, an iridoid, is an autophagy enhancer. Valechlorine is effective in alleviating fatty liver by acting as an autophagy enhancer to break down lipid droplets. Valechlorine can be used for the study of nonalcoholic fatty liver disease (NAFLD) .
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Cat. No.: HY-N0901B
Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
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Cat. No.: HY-163136A
Target:  

Autophagy REV-ERB

Research Areas:  

Cancer

Autophagy/REV-ERB-IN-1 hydrochloride (Compound 24) is a dual autophagy and REV-ERB inhibitor with anticancer activity. Autophagy/REV-ERB-IN-1 (hydrochloride) has improved potency in blocking autophagy, enhanced toxicity against cancer cells. Autophagy/REV-ERB-IN-1 (hydrochloride) can be used for the research for melanoma .
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