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auxiliary reagent

" in MedChemExpress (MCE) Product Catalog:

145

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137

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140

Biochemical Assay Reagents

3

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132

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10583G
    Y-27632 dihydrochloride
    1 Publications Verification

    		 ROCK Neurological Disease Cancer
    Y-27632 dihydrochloride (GMP) is the GMP level of Y-27632 dihydrochloride (HY-10583). GMP guidelines are used to produce Y-27632 dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor with antiepileptic effect .
    Y-27632 dihydrochloride
  • HY-10182G
    Laduviglusib
    2 Publications Verification

    CHIR-99021; CT99021

    		 GSK-3 Wnt β-catenin Autophagy Metabolic Disease Cancer
    Laduviglusib (CHIR-99021) (GMP) is Laduviglusib (HY-10182) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Laduviglusib is a potent, orally active and selective GSK-3α/β inhibitor.
    Laduviglusib
  • HY-10431G
    SB-431542

    		TGF-β Receptor Neurological Disease Cancer
    SB-431542 (GMP) is SB-431542 (HY-10431) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SB-431542 is a TGF-β receptor kinase inhibitor (TRKI) in SMAD signaling .
    SB-431542
  • HY-13012G
    RepSox

    E-616452; SJN 2511

    		 TGF-β Receptor Metabolic Disease
    RepSox (E-616452) (GMP) is a RepSox (HY-13012) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor .
    RepSox
  • HY-15162G
    Monomethyl auristatin E

    MMAE; SGD-1010; Vedotin

    		 Microtubule/Tubulin Apoptosis ADC Payload Cancer
    Monomethyl auristatin E (MMAE) (GMP) is Monomethyl auristatin E (HY-15162) produced by using GMP guidelines. Monomethyl auristatin E is a tubulin polymerization inhibitor .
    Monomethyl auristatin E
  • HY-B0166G
    L-Ascorbic acid

    L-Ascorbate; Vitamin C

    		 Reactive Oxygen Species (ROS) Calcium Channel Apoptosis Endogenous Metabolite Neurological Disease Metabolic Disease Cancer
    L-Ascorbic acid (L-Ascorbate) (GMP) is Ascorbic acid (HY-B0166) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. L-Ascorbic acid is an inhibitor of Cav 3.2 channels .
    L-Ascorbic acid
  • HY-14649G
    Retinoic acid

    Vitamin A acid; all-trans-Retinoic acid; ATRA

    		 RAR/RXR PPAR Endogenous Metabolite Autophagy Cancer
    Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors .
    Retinoic acid
  • HY-14648G
    Dexamethasone
    3 Publications Verification

    Hexadecadrol; Prednisolone F

    		 Glucocorticoid Receptor ADC Payload Infection Inflammation/Immunology Endocrinology Cancer
    Dexamethasone (Hexadecadrol) (GMP) is Dexamethasone (HY-14648) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Dexamethasone is an agonist of glucocorticoid receptor .
    Dexamethasone
  • HY-101952G
    Prostaglandin E2

    PGE2; Dinoprostone

    		 Endogenous Metabolite Cardiovascular Disease Endocrinology
    Prostaglandin E2 (GMP) is Prostaglandin E2 (HY-101952) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Prostaglandin E2, an inflammatory mediator, is a endogenous hormone-like substance that participate in a wide range of body functions .
    Prostaglandin E2
  • HY-A0070AG
    Liothyronine
    1 Publications Verification

    Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3

    		 Thyroid Hormone Receptor Endocrinology Cancer
    Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively .
    Liothyronine
  • HY-13631EG
    Deruxtecan

    MC-GGFG-DXD

    		 Drug-Linker Conjugates for ADC Cancer
    Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
    Deruxtecan
  • HY-13027G
    DAPT

    GSI-IX

    		 γ-secretase Neurological Disease Inflammation/Immunology Cancer
    DAPT (GSI-IX) (GMP) is DAPT (HY-13027) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DAPT is a potent and orally active γ-secretase inhibitor .
    DAPT
  • HY-10254G
    Mirdametinib
    1 Publications Verification

    PD0325901; PD325901

    		 MEK Cancer
    Mirdametinib (PD0325901) (GMP) is Mirdametinib (HY-10254) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Mirdametinib is an orally active, selective and non-ATP-competitive MEK inhibitor .
    Mirdametinib
  • HY-13257G
    Thiazovivin

    		ROCK Cancer
    Thiazovivin (GMP) is Thiazovivin (HY-13257) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Thiazovivin is a potent ROCK inhibitor .
    Thiazovivin
  • HY-10432G
    A 83-01

    		Anaplastic lymphoma kinase (ALK) Cancer
    A 83-01 (GMP) is A 83-01 (HY-10432) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. A 83-01 is a potent ALK4/5/7 inhibitor .
    A 83-01
  • HY-B0445GL
    NAD+ (GMP Like)

    β-DPN (GMP Like); β-NAD (GMP Like); β-Nicotinamide Adenine Dinucleotide (GMP Like)

    		 Endogenous Metabolite Metabolic Disease
    NAD+ (GMP Like) is NAD+ (HY-B0445) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
    NAD+ (GMP Like)
  • HY-40229
    (S)-(-)-tert-Butylsulfinamide

    S-(-)-T-Butylsulfinimide

    		 Biochemical Assay Reagents Others
    (S)-(-)-tert-Butylsulfinamide (S-(-)-T-Butylsulfinimide) is a compound containing a chiral sulfur atom. (S)-(-)-tert-Butylsulfinamide can be used in the synthesis of other compounds .
    (S)-(-)-tert-Butylsulfinamide
  • HY-12318G
    IBMX

    3-Isobutyl-1-methylxanthine; Isobutylmethylxanthine

    		 Phosphodiesterase (PDE) Inflammation/Immunology
    IBMX (3-Isobutyl-1-methylxanthine) (GMP) is IBMX (HY-12318) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor .
    IBMX
  • HY-15659G
    Wnt-C59

    C59

    		 Porcupine Wnt Cancer
    Wnt-C59 (C59) GMP is a GMP grade Wnt-C59 (HY-15659). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Wnt-C59 (C59) is a highly potent and oral porcupine (PORCN) inhibitor with an IC50 of 74 pM.
    Wnt-C59
  • HY-13740G
    Resiquimod

    R848; S28463

    		 Toll-like Receptor (TLR) Inflammation/Immunology Cancer
    Resiquimod (R848) (GMP) is Resiquimod (HY-13740) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist. Resiquimod (GMP) can induce human mMDSC to mature into inflammatory macrophages .
    Resiquimod
  • HY-59125
    (R,R)-(+)-Hydrobenzoin

    		Endogenous Metabolite Others
    (R,R)-(+)-Hydrobenzoin is a chiral secondary alcohol that can be used as a key substrate or a chiral auxiliary reagent in various catalytic reactions and synthetic experiments .
    (R,R)-(+)-Hydrobenzoin
  • HY-15147G
    XAV-939

    		PARP Neurological Disease Cancer
    XAV-939 (GMP) is XAV-939 (HY-15347) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. XAV-939 is a tankyrase inhibitor .
    XAV-939
  • HY-18085G
    Quercetin
    1 Publications Verification

    		 PI3K Autophagy Mitophagy Apoptosis Reactive Oxygen Species (ROS) Cancer
    Quercetin GMP is Quercetin (HY-18085) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Quercetin is a flavonoid antioxidant, a PI3K inhibitor and a SIRT1 Activator .
    Quercetin
  • HY-15141G
    Staurosporine

    Antibiotic AM-2282; STS; AM-2282

    		 PKC Infection Cancer
    Staurosporine (AM-2282) (GMP) is Staurosporine (HY-15141) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases .
    Staurosporine
  • HY-13912G
    IWP-2
    1 Publications Verification

    		 Wnt Cancer
    IWP-2 (GMP) is >IWP-2 (HY-13912) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and blocks Wnt ligand palmitoylation .
    IWP-2
  • HY-10219G
    Rapamycin

    Sirolimus; AY-22989; NSC 226080

    		 mTOR FKBP Fungal Autophagy Endogenous Metabolite Antibiotic Bacterial Infection Cancer
    Rapamycin (Sirolimus) (GMP) is Rapamycin (HY-10219) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 . Rapamycin is an autophagy activator, an immunosuppressant .
    Rapamycin
  • HY-112754AGL
    DOTAP chloride (GMP Like)

    1,2-Dioleoyl-3-trimethylammonium-propane chloride (GMP Like)

    		 Liposome Others
    DOTAP chloride (GMP Like) is the GMP Like class DOTAP chloride (HY-112754A). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAP chloride is a cationic lipid with good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can be used as an excipient for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of helper lipid .
    DOTAP chloride (GMP Like)
  • HY-10219GL
    Rapamycin (GMP Like)

    Sirolimus (GMP Like); AY-22989 (GMP Like); NSC 226080 (GMP Like)

    		 mTOR FKBP Fungal Autophagy Endogenous Metabolite Antibiotic Bacterial Cancer
    Rapamycin (Sirolimus) GMP Like is Rapamycin (HY-10219) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 . Rapamycin is an autophagy activator, an immunosuppressant .
    Rapamycin (GMP Like)
  • HY-134541GL
    SM-102 (GMP Like)

    		Liposome Infection
    SM-102 (GMP Like) is SM-102 (HY-134541) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102 (GMP Like)
  • HY-15108G
    Purmorphamine
    1 Publications Verification

    		 Smo Neurological Disease Cancer
    Purmorphamine (GMP) is Purmorphamine (HY-15108) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Purmorphamine is a smoothened/Smo receptor agonist with an EC50 of 1 μM .
    Purmorphamine
  • HY-15682G
    TTNPB

    Ro 13-7410; Arotinoid acid; AGN191183

    		 RAR/RXR Cancer
    TTNPB (Ro 13-7410) (GMP) is TTNPB (HY-15682) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. TTNPB is a highly potent retinoic acid receptor (RAR) agonist .
    TTNPB
  • HY-13418G
    Dorsomorphin dihydrochloride

    Compound C dihydrochloride; BML-275 dihydrochloride

    		 AMPK Neurological Disease Cancer
    Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418). GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs) .
    Dorsomorphin dihydrochloride
  • HY-134541G
    SM-102

    		Liposome Infection
    SM-102 (GMP) is SM-102 (HY-134541) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102
  • HY-12848G
    SAG

    		Smo Cancer
    SAG (GMP) is SAG (HY-12848) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo .
    SAG
  • HY-112251GL
    D-Lin-MC3-DMA (GMP Like)

    		Liposome Cancer
    D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
    D-Lin-MC3-DMA (GMP Like)
  • HY-15579G
    MMAF

    Monomethylauristatin F

    		 Microtubule/Tubulin ADC Payload Cancer
    MMAF (Monomethylauristatin F) GMP is a GMP grade MMAF (HY-15579). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A .
    MMAF
  • HY-W010394
    Methyl 3-oxopentanoate

    		Biochemical Assay Reagents Others
    Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions.
    Methyl 3-oxopentanoate
  • HY-17447AG
    Tranylcypromine hydrochloride

    SKF 385 hydrochloride

    		 Monoamine Oxidase Cardiovascular Disease Endocrinology
    Tranylcypromine (SKF 385) hydrochloride (GMP) is Tranylcypromine hydrochloride (HY-17447A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Tranylcypromine hydrochloride is a potent monoamine oxidase (MAO) inhibitor .
    Tranylcypromine hydrochloride
  • HY-13506G
    M344 (GMP)

    D 237 (GMP); MS 344 (GMP)

    		 HDAC Cancer
    M344 (GMP) (D 237) (GMP) is the GMP level of M344 (HY-13506). GMP level of small molecules can be used as auxiliary reagents in cell therapy. M344 is a kind of histone acetylation enzyme inhibitor .
    M344 (GMP)
  • HY-138300GL
    ALC-0159 (GMP Like)

    		Liposome Inflammation/Immunology
    ALC-0159 (GMP Like) is the GMP Like class ALC-0159 (HY-138300). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient .
    ALC-0159 (GMP Like)
  • HY-10407G
    SU 5402

    		VEGFR EGFR PDGFR Cancer
    SU 5402 (GMP) is SU 5402 (HY-10407) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGFRβ, respectively .
    SU 5402
  • HY-148748G
    Butyzamide

    		JAK STAT p38 MAPK Cardiovascular Disease
    Butyzamide (GMP) is Butyzamide (HY-148748) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Butyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of platelets in mouse xenotransplantation assay .
    Butyzamide
  • HY-14823G
    Sobetirome

    GC-1; QRX-431

    		 Thyroid Hormone Receptor Metabolic Disease Endocrinology
    Sobetirome (GMP) is Sobetirome (HY-14823) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Sobetirome (GC-1) is a thyroid hormone receptor β (TRβ)-specific agonist which bind selectively to TRβ-1 with an EC50 of 0.16 μM .
    Sobetirome
  • HY-N0737AG
    Harmine

    Telepathine

    		 DYRK 5-HT Receptor Neurological Disease Inflammation/Immunology Cancer
    Harmine (GMP) (Telepathine (GMP)) is Harmine (HY-N0737A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Harmine is a natural dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT2A serotonin receptor, with an Ki of 397 nM .
    Harmine
  • HY-100224G
    SANT-1

    		Smo Hedgehog Cancer
    SANT-1 (GMP) is SANT-1 (HY-100224) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SANT-1, a potent Smo antagonist, inhibits Hedgehog signaling .
    SANT-1
  • HY-78932G
    Dap-NE hydrochloride

    		ADC Linker Cancer
    Dap-NE hydrochloride (GMP) is Dap-NE hydrochloride (HY-78932A) produced by using GMP guidelines. Dap-NE hydrochloride is an intermediate used in the synthesis of antibody-drug conjugates (ADCs) .
    Dap-NE hydrochloride
  • HY-12323G
    ISX-9

    Isoxazole 9

    		 Calcium Channel Cardiovascular Disease Neurological Disease
    ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation.
    ISX-9
  • HY-12362G
    Val-cit-PAB-OH

    		ADC Linker Cancer
    Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Val-cit-PAB-OH is a degradable ADC linker.
    Val-cit-PAB-OH
  • HY-50895G
    Gefitinib

    ZD1839

    		 EGFR Autophagy Apoptosis Cancer
    Gefitinib (ZD1839) (GMP) is Gefitinib (HY-50895) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Gefitinib is a potent, selective and orally active EGFR tyrosine kinase inhibitor .
    Gefitinib
  • HY-10475G
    AM580

    CD336; NSC608001; Ro 40-6055

    		 RAR/RXR Cancer
    AM580 (CD336) (GMP) is AM580= (HY-10475) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. AM580 is a selective RARα agonist .
    AM580

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