DAPT (Synonyms: GSI-IX)

Cat. No.: HY-13027G: FAQs
Data Sheet Handling Instructions

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DAPT (GSI-IX) (GMP) is DAPT (HY-13027) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DAPT is a potent and orally active γ-secretase inhibitor.

For research use only. We do not sell to patients.

DAPT Chemical Structure

CAS No. : 208255-80-5

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Description	DAPT (GSI-IX) (GMP) is DAPT (HY-13027) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DAPT is a potent and orally active γ-secretase inhibitor^[1]^[2].
In Vitro	DAPT (GMP) (9 d) induces human induced pluripotent stem cells develop into expandable myoblasts^[1]. DAPT (GMP) (13 d) induces human pluripotent stem cells (hPSCs) develop into functional neurons^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. DAPT Related Antibodies
Molecular Weight	432.46
Formula	C₂₃H₂₆F₂N₂O₄
CAS No.	208255-80-5
SMILES	FC1=CC(F)=CC(CC(N[C@H](C(N[C@H](C(OC(C)(C)C)=O)C2=CC=CC=C2)=O)C)=O)=C1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (270 KB) Handling Instructions (2659 KB)
References	[1]. Choi IY, et al. Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model. Cell Rep. 2016 Jun 7;15(10):2301-2312. [Content Brief] [2]. Qi Y, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017 Feb;35(2):154-163. [Content Brief]

DAPT Related Classifications

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Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DAPT (GMP)208255-80-5GSI-IX (GMP)γ-secretaseGamma secretaseGMPcell therapy manufacturepotentoralhiPSCmyoblastneuronsInhibitorinhibitorinhibit

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DAPT (Synonyms: GSI-IX)

Other Forms of DAPT:

DAPT Related Antibodies

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•Related Small Molecules:

•Related Proteins:

Biological Activity

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References

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