12 Results for "

bestatin ligand

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "bestatin ligand" in MCE Product Catalog:

Cat. No.: HY-111872
CAS No.: 3093563-31-3
Purity:  99.79%
Target:  

SNIPERs Bcr-Abl

Research Areas:  

Cancer

SNIPER(ABL)-020, conjugating Dasatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein .
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Cat. No.: HY-111860
Target:  

SNIPERs Bcr-Abl

Research Areas:  

Cancer

SNIPER(ABL)-013, conjugating GNF5 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 20 μM .
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Cat. No.: HY-111850
CAS No.: 339186-54-8
Synonyms: PROTAC IAP binding moiety 1
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

Bestatin-amido-Me, the Bestatin-based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER .
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Cat. No.: HY-111878
CAS No.: 2443928-42-3
Target:  

SNIPERs

Research Areas:  

Cancer

BzNH-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase .
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Cat. No.: HY-168318
Research Areas:  

Cancer

Bestatin-amide-PEG3-CH2-acid is an E3 ligase ligand-linker conjugate. Bestatin-amide-PEG3-CH2-acid can be used to synthesize PROTAC RAR Degrader-1 (HY-111844) .
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Cat. No.: HY-111839
CAS No.: 135325-47-2
Synonyms: CRABP-II ligand 1
Research Areas:  

Cancer

ATRA-hydroxyimino (CRABP-II ligand 1), the Retinoic acid (ATRA)-based moiety, binds to cIAP1 ligand (Bestatin) via a linker to form SNIPER to degrade CRABP-II in IMR-32 cells .
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Cat. No.: HY-111879
Target:  

SNIPERs

Research Areas:  

Cancer

Biotin-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and biotin, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase .
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Cat. No.: HY-111851
Target:  

SNIPERs Bcr-Abl

Research Areas:  

Cancer

SNIPER(ABL)-049, conjugating Imatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 100 μM .
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Cat. No.: HY-111862
Target:  

SNIPERs Bcr-Abl

Research Areas:  

Cancer

SNIPER(ABL)-044, conjugating HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM .
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Cat. No.: HY-111845
CAS No.: 138219-84-8
Synonyms: ERα ligand 1
Estrone-N-O-C1-amido (ERα ligand 1) is an Estrone-based estrogen ligand, which targets estrogen receptor α (ERα). Estrone-N-O-C1-amido (ERα ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER .
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Cat. No.: HY-111843
CAS No.: 144298-98-6
Synonyms: RAR ligand 1
Ch55-O-C3-NH2 (RAR ligand 1) is a Ch 55-based ligand, which targets RAR. Ch55-O-C3-NH2 (RAR ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER .
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Cat. No.: HY-181318
CAS No.: 3093642-35-1
Research Areas:  

Cancer

PROTAC EZH2 Degrader-20 (compound 54) is an EZH2-target PROTAC degrader with antiproliferative activity and IC50 values of about 10 μM against lymphoma cells. PROTAC EZH2 Degrader-20 can be used for the research of lymphoma .
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