Estrone-N-O-C1-amido
Estrone-N-O-C1-amido (ERα ligand 1) is an Estrone-based estrogen ligand, which targets estrogen receptor α (ERα). Estrone-N-O-C1-amido (ERα ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER.
For research use only. We do not sell to patients.
- CAS No.: 138219-84-8
- Formula: C20H26N2O3
- Molecular Weight:342.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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I-BET762 carboxylic acid (Standard)Reference Standard -
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SLF-amido-C2-COOH (Standard)Reference Standard
Biological Activity
Description
Chemical Information
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CAS No. 138219-84-8
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Molecular Weight 342.43
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Formula C20H26N2O3
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SMILES
O=C(N)CO/N=C1CC[C@]2([H])[C@]\1(C)CC[C@@]3([H])[C@@]2([H])CCC4=C3C=CC(O)=C4
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Synonyms
ERα ligand 1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Estrone-N-O-C1-amido Related Classifications
HY-111845 Related Classifications
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