12 Results for "

calcitonin receptor (CTR)

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "calcitonin receptor (CTR)" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P3462
CAS No.: 1415456-99-3
Target:  

CGRP Receptor

Research Areas:  

Metabolic Disease

Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity .
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Cat. No.: HY-179738
CAS No.: 3097482-67-9
Research Areas:  

Metabolic Disease

CTR/AMYR modulator-1 is a calcitonin receptor/amylin receptor modulator. CTR/AMYR modulator-1 can be used for the research of metabolic disease .
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Cat. No.: HY-P4863
CAS No.: 1678415-18-3
Target:  

CGRP Receptor

Biotinyl-Amylin (human) is a biotin-labeled derivative of Amylin, amide, human (HY-P1070). Biotinyl-Amylin (human) acts as a competitive agonist for the Calcitonin Receptor (CTR) and for the Amylin receptors (AMY1, AMY2, and AMY3) formed by the association of CTR with RAMP1/2/3. By mimicking endogenous human amylin, Biotinyl-Amylin (human) binds to and activates CTR and AMY receptors, thereby initiating downstream signaling pathways involving cAMP, CREB, and ERK1/2, while retaining high-affinity receptor binding and activation capabilities. Biotinyl-Amylin (human) is primarily utilized in studies investigating the metabolic regulatory mechanisms underlying obesity and diabetes; it is also applicable to pharmacological research, receptor localization studies, and ligand-binding assays related to Amylin receptors in the context of Alzheimer's disease .
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Cat. No.: HY-P11586
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

San45 is a nonselective dual amylin and calcitonin receptor agonist (DACRA) with nonselective potency relative to calcitonin receptor (CTR) and amylin 1 receptor (AMY₁R), and acts as a stabilizer of receptor-ligand complex and prolonged activator of cAMP signaling. San45 carries a conjugated lipid modification that can be used for the research of obesity .
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Cat. No.: HY-P74359
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CALCR; CTR; calcitonin receptor; CTR1; CT-R; CRT
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-186104
CAS No.: 3097592-82-7
Research Areas:  

Metabolic Disease

AMYR/CTR agonist 1 is an amylin receptor (AMYR) and calcitonin receptor (CTR) agonist with an amylin receptor cAMP stimulation EC50 of 0.0995 nM and a calcitonin receptor cAMP stimulation EC50 of 0.00616 nM. AMYR/CTR agonist 1 can be used for the research of non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, insulin dependent diabetes, non-insulin dependent diabetes, impaired glucose tolerance, obesity, syndrome x .
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Cat. No.: HY-185107
CAS No.: 3108095-52-6
Research Areas:  

Metabolic Disease

CTR/AMYR modulator-2 is a dual agonist of human amylin receptor 3 (AMY3R) and calcitonin receptor (CTR). CTR/AMYR modulator-2 activates AMY3R and CTR, stimulating Rel EC50 of cAMP production in UMUC3 cells by 4 nM and 1 nM, respectively. CTR/AMYR modulator-2 may be used in research on type 2 diabetes and obesity .
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Cat. No.: HY-185229B
CAS No.: 3108096-13-2
Research Areas:  

Metabolic Disease

rel-CTR/AMYR agonist-1 is an agonist of amylin and/or calcitonin receptor. rel-CTR/AMYR agonist-1 can be used in research on metabolic diseases such as type 2 diabetes and obesity .
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Cat. No.: HY-187461
CAS No.: 3138389-44-0
Research Areas:  

Metabolic Disease

CTR/AMYR agonist-2 is a fused heterocyclic amide/sulfonamide compound, as well as a calcitonin G protein-coupled receptor (CGRP Receptor) / amylin receptor agonist. CTR/AMYR agonist-2 shows potential for application in research related to diseases such as obesity and type 2 diabetes .
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Cat. No.: HY-179728
Research Areas:  

Metabolic Disease

Amylin agonist 1 is an agonist of amylin receptor 3 (AMY3R), with an EC50 of 6.17 nM for stimulating cellular cAMP production. Amylin agonist 1 is also an agonist of calcitonin receptor (CTR), with an EC50 of 8.58 nM. Amylin agonist 1 can be used for the research of type 2 diabetes and obesity .
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Cat. No.: HY-P11843
Research Areas:  

Metabolic Disease

TPM004 is an ultralong-acting, nonaggregating dual amylin (AMY3R) and calcitonin receptor (CTR) agonist with EC50 values of 0.5 and 0.7 pM. TPM004 induces weight loss, attenuates adiposity rebound, lowers glucose, and improves glucose homeostasis. TPM004 can be used for the research of obesity, diabetes .
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Cat. No.: HY-P11584
Research Areas:  

Metabolic Disease

KBP-066A is a long-acting dual amylin and calcitonin receptor agonist. KBP-066A can activate the CTR and AMY-R potently, with no off-target activity. KBP-066A reduces fasting blood glucose levels, fasting insulin levels, and body weight in diabetic rat models. KBP-066A can be used for the research of type 2 diabetes mellitus, obesity .
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