28 Results for "

calcitonin receptor agonist

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "calcitonin receptor agonist" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P0090
CAS No.: 47931-85-1
Synonyms: Salmon calcitonin
Target:  

CGRP Receptor

Research Areas:  

Cancer

Calcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption.
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3
3 Cited Publications
Cat. No.: HY-P3462
CAS No.: 1415456-99-3
Target:  

CGRP Receptor

Research Areas:  

Metabolic Disease

Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity .
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3
3 Cited Publications
Cat. No.: HY-P0090A
CAS No.: 158000-61-4
Synonyms: Salmon calcitonin acetate
Target:  

CGRP Receptor

Research Areas:  

Cancer

Calcitonin (salmon) (acetate) is a dual-action amylin and calcitonin receptor agonist, can stimulate bone formation and inhibit bone resorption .The acetate form can affect the absorption and efficacy of hormones .
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1
1 Cited Publications
Cat. No.: HY-P1072
CAS No.: 87403-73-4
Target:  

CGRP Receptor

PHM-27 (human) is a human prepro-vasoactive intestinal polypeptide (27 amino acid). PHM-27 (human) is a potent the human calcitonin receptor agonist with an EC50 of 11 nM. PHM-27 (human) efficiently enhances glucose-induced insulin secretion from beta cells by an autocrine mechanism .
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Cat. No.: HY-P10745
CAS No.: 2766385-23-1
Synonyms: ZP8396
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Petrelintide (ZP8396) is a dual amylin and calcitonin receptor agonist (DACRA) Petrelintide elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Petrelintide can be utilized in diabetes research .
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Cat. No.: HY-P11274A
Synonyms: Amycretin sodium; NN 9487 sodium
Research Areas:  

Metabolic Disease

Zenagamtide (Amycretin; NN 9487) sodium is an orally active, blood-brain barrier permeable triple agonist that targets GLP-1, amylin (Amylin Receptor) and calcitonin receptor (Calcitonin Receptor). Zenagamtide sodium is a single peptide consisting of 68 amino acids that can target brain regions regulating food intake, significantly suppress appetite and reduce energy intake. Therefore, Zenagamtide sodium improves body weight, waist circumference, glycated hemoglobin and lipid profile, and also alleviates the histological features of metabolic dysfunction-associated steatotic liver disease (MASLD) and enhances insulin sensitivity. Zenagamtide sodium may cause transient increases in heart rate and fluctuations in serum calcium levels, but it is an important compound for the study of overweight, obesity, insulin resistance and related metabolic diseases .
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Cat. No.: HY-P10745A
Synonyms: ZP8396 acetate
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Perelintide (ZP8396) acetate is a dual amylin and calcitonin receptor agonist (DACRA). Perelintide acetate elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Perelintide acetate can be utilized in diabetes research .
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Cat. No.: HY-P10956
CAS No.: 2891912-36-8
Synonyms: LY3541105
Research Areas:  

Metabolic Disease

Colulintide (LY3541105) is an amylin-calcitonin dual receptor agonist with Amylin as its scaffold. Colulintide is applicable to research related to type 2 diabetes and obesity .
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Cat. No.: HY-P11274
CAS No.: 3005889-81-3
Synonyms: Amycretin; NN 9487
Research Areas:  

Metabolic Disease

Zenagamtide (Amycretin; NN 9487) is an orally active, blood-brain barrier permeable triple agonist that targets GLP-1, amylin (Amylin Receptor) and calcitonin receptor (Calcitonin Receptor). Zenagamtide is a single peptide consisting of 68 amino acids that can target brain regions regulating food intake, significantly suppress appetite and reduce energy intake. Therefore, Zenagamtide improves body weight, waist circumference, glycated hemoglobin and lipid profile, and also alleviates the histological features of metabolic dysfunction-associated steatotic liver disease (MASLD) and enhances insulin sensitivity. Zenagamtide may cause transient increases in heart rate and fluctuations in serum calcium levels, but it is an important compound for the study of overweight, obesity, insulin resistance and related metabolic diseases .
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Cat. No.: HY-103302
CAS No.: 345893-91-6
Purity:  99.89%
Target:  

CGRP Receptor

Research Areas:  

Endocrinology

SUN B8155, a non-peptide agonist of calcitonin (CT) receptor, selectively mimics the biological actions of calcitonin. Calcitonin, a 32-amino acid peptide hormone secreted mainly from the thyroid gland, plays an important role in maintaining bone homeostasis .
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Cat. No.: HY-P11320
CAS No.: 863919-85-1
Research Areas:  

Metabolic Disease

Davalintide is an Amylin (HY-P1464)-mimetic peptide with greater potency and longer-lasting effects. Davalintide is a potent agonist of amylin receptor (IC50 = 0.04 nM), calcitonin receptor (IC50 = 0.06 nM) and calcitonin related peptide receptor (CGRP receptor) (IC50 = 3.1 nM). Davalintide shows stronger potency to Amylin to activate cyclic AMP production through the calcitonin receptor (EC50 = 1.4 nM). Davalintide regulates blood sugar and weight through various mechanisms such as delaying gastric emptying, inhibiting glucagon secretion, and reducing food intake. Davalintide can be used for the studies of anti-obesity and anti-diabetes .
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Cat. No.: HY-121300
CAS No.: 183202-73-5
Purity:  98.00%
Synonyms: (-)-TAN2162
Kendomycin ((−)-TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 μg/mL). Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent .
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Cat. No.: HY-P11269
CAS No.: 2793341-99-6
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Lenbelintide is a dual amylin/calcitonin receptor agonist. Lenbelintide can be studied in research on obesity .
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Cat. No.: HY-P0090S
Synonyms: Salmon calcitonin-13C6,15N4 TFA
Target:  

CGRP Receptor

Research Areas:  

Metabolic Disease

Calcitonin- 13C6, 15N4 (salmon) (Salmon calcitonin- 13C6, 15N4) TFA is 13C and 15N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .
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Cat. No.: HY-P4863
CAS No.: 1678415-18-3
Target:  

CGRP Receptor

Biotinyl-Amylin (human) is a biotin-labeled derivative of Amylin, amide, human (HY-P1070). Biotinyl-Amylin (human) acts as a competitive agonist for the Calcitonin Receptor (CTR) and for the Amylin receptors (AMY1, AMY2, and AMY3) formed by the association of CTR with RAMP1/2/3. By mimicking endogenous human amylin, Biotinyl-Amylin (human) binds to and activates CTR and AMY receptors, thereby initiating downstream signaling pathways involving cAMP, CREB, and ERK1/2, while retaining high-affinity receptor binding and activation capabilities. Biotinyl-Amylin (human) is primarily utilized in studies investigating the metabolic regulatory mechanisms underlying obesity and diabetes; it is also applicable to pharmacological research, receptor localization studies, and ligand-binding assays related to Amylin receptors in the context of Alzheimer's disease .
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Cat. No.: HY-185229B
CAS No.: 3108096-13-2
Research Areas:  

Metabolic Disease

rel-CTR/AMYR agonist-1 is an agonist of amylin and/or calcitonin receptor. rel-CTR/AMYR agonist-1 can be used in research on metabolic diseases such as type 2 diabetes and obesity .
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Cat. No.: HY-P11665
CAS No.: 3034703-92-6
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Batelintide is a dual amylin/calcitonin receptor agonist with antidiabetic effects .
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Cat. No.: HY-186104
CAS No.: 3097592-82-7
Research Areas:  

Metabolic Disease

AMYR/CTR agonist 1 is an amylin receptor (AMYR) and calcitonin receptor (CTR) agonist with an amylin receptor cAMP stimulation EC50 of 0.0995 nM and a calcitonin receptor cAMP stimulation EC50 of 0.00616 nM. AMYR/CTR agonist 1 can be used for the research of non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, insulin dependent diabetes, non-insulin dependent diabetes, impaired glucose tolerance, obesity, syndrome x .
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Cat. No.: HY-P11586
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

San45 is a nonselective dual amylin and calcitonin receptor agonist (DACRA) with nonselective potency relative to calcitonin receptor (CTR) and amylin 1 receptor (AMY₁R), and acts as a stabilizer of receptor-ligand complex and prolonged activator of cAMP signaling. San45 carries a conjugated lipid modification that can be used for the research of obesity .
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Cat. No.: HY-187461
CAS No.: 3138389-44-0
Research Areas:  

Metabolic Disease

CTR/AMYR agonist-2 is a fused heterocyclic amide/sulfonamide compound, as well as a calcitonin G protein-coupled receptor (CGRP Receptor) / amylin receptor agonist. CTR/AMYR agonist-2 shows potential for application in research related to diseases such as obesity and type 2 diabetes .
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