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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
593 Results for "
cell adhesion ;
" in MedChemExpress (MCE) Product Catalog:
Products (593)
593 Results for "cell adhesion ;" in MCE Product Catalog:
488
488 Publications Verification
Synonyms: BAY 11-7821
Target:
Áreas de investigación:
BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells .
213
213 Cited Publications
Referencia número: HY-B0579
No. CAS: 59865-13-3
Synonyms: Cyclosporine A; Ciclosporin A; CsA
29
29 Cited Publications
Synonyms: FAK Inhibitor 14
Y15 is a potent and specific inhibitor of focal adhesion kinase (FAK) that inhibits its autophosphorylation activity, decreases the viability of cancer cells, and blocks tumor growth.
21
Target:
21
21 Cited Publications
Synonyms: Hyaluronan; Hyaluronate
Category:
Zea mays L. Moisture Plants Endogenous metabolite Human Gut Microbiota Metabolites Polysaccharides Gramineae Cosmetic Research Disease Research Fields Saccharides Cancer
Target:
15
15 Cited Publications
Target:
Áreas de investigación:
K-7174 is an orally active proteasome and GATA inhibitor. K-7174 is a cell adhesion inhibitor. K-7174 induces cell apoptosis. K-7174 shows antitumor activities, it can be used for the research of cancer .
15
15 Cited Publications
Target:
Áreas de investigación:
K-7174 dihydrochloride is an orally active proteasome and GATA inhibitor. K-7174 dihydrochloride is a cell adhesion inhibitor. K-7174 dihydrochloride induces cell apoptosis. K-7174 dihydrochloride shows antitumor activities, it can be used for the research of cancer .
13
13 Cited Publications
GSK-2256098 hydrochloride is a focal adhesion kinase (FAK) inhibitor that exhibits potential antiangiogenic and antineoplastic activities. GSK-2256098 hydrochloride targets FAK to inhibit tumor cell growth by regulating cell adhesion, migration, proliferation, and survival.
11
11 Cited Publications
Referencia número: HY-P9915
No. CAS: 945721-28-8
Synonyms: Anti-Human CD38, Human Antibody; HuMax-CD38; JNJ-54767414
Target:
Áreas de investigación:
11
11 Cited Publications
Referencia número: HY-P9915A
No. CAS: 945721-28-8
Synonyms: Anti-Human CD38, Human Antibody (PBS)
Target:
Áreas de investigación:
11
Target:
Áreas de investigación:
Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease .
11
11 Cited Publications
Referencia número: HY-19344A
No. CAS: 1119276-80-0
Synonyms: SAR 1118 sodium; SHP-606 sodium
Target:
Áreas de investigación:
Lifitegrast (SAR 1118) sodium is a potent integrin antagonist. Lifitegrast sodium blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast sodium can be used for researching dry eye disease .
11
10
10
10 Cited Publications
9
9
9 Cited Publications
Referencia número: HY-P1740
No. CAS: 114681-65-1
Áreas de investigación:
9
9 Cited Publications
Referencia número: HY-P1740A
Áreas de investigación:
9
9 Cited Publications
Referencia número: HY-P0278A
No. CAS: 2378808-45-6
7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
