Search Result
Results for "
chickens
" in MedChemExpress (MCE) Product Catalog:
13
Biochemical Assay Reagents
13
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B1205
-
-
-
- HY-B2237
-
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Bacterial
HIV
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Infection
|
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Lysozyme from chicken egg white is a bactericidal enzyme, and it lyses gram-positive bacteria.
Lysozyme from chicken egg white can also be used for the research of HIV infection and pulmonary emphysema .
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-
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- HY-B0631
-
|
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NF-κB
Interleukin Related
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Metabolic Disease
|
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Alendronate acid is an orally active bisphosphonate which binds to bone surfaces and inhibits bone resorption by osteoclasts. Alendronate acid induces skeletal alterations in the chicken embryonic development model. Alendronate acid can be used for osteoporosis research .
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- HY-118122
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FIAU; DRG-0098; NSC 678514
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HSV
HBV
DNA/RNA Synthesis
Orthopoxvirus
Nucleoside Antimetabolite/Analog
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Infection
|
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Fialuridine (FIAU), a nucleoside analog, is a HSV-1 and HSV-2 inhibitor with Kis of 0.14 μM and 0.95 μM, respectively. Fialuridine shows anti-orthopoxvirus and anti-hepatitis B virus (HBV) activities. Fialuridine inhibits duck HBV DNA replication with IC50 values of 0.075 μM and 156 μM in human hepatoma cells and in chicken liver cells, respectively .
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- HY-108685
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Alendronic acid monosodium salt
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NF-κB
Interleukin Related
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Metabolic Disease
|
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Alendronate sodium is an orally active bisphosphonate which binds to bone surfaces and inhibits bone resorption by osteoclasts. Alendronate sodium induces skeletal alterations in the chicken embryonic development model. Alendronate sodium can be used for osteoporosis research .
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- HY-N1500
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-
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- HY-B0278
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Zinc bacitracin
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Environmental Pollutants
Antibiotic
Bacterial
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Infection
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Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle .
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- HY-P2232
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- HY-B0394
-
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Tropine tropate sulfate monohydrate; DL-Hyoscyamine sulfate monohydrate
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mAChR
|
Cardiovascular Disease
Neurological Disease
Cancer
|
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Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .
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- HY-B1337S1
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Cholinesterase (ChE)
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Others
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Choline-d9 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
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- HY-B1205A
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Tropine tropate sulfate; DL-Hyoscyamine sulfate; Sulfatropinol
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mAChR
|
Cardiovascular Disease
Neurological Disease
Cancer
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Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .
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-
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- HY-W004307
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Stearyl aldehyde
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Endogenous Metabolite
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Others
|
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Octadecanal (Stearyl aldehyde) is a long-chain aldehyde component. Octadecanal exists in the phospholipid fractions of thigh and breast muscles of broiler chickens .
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- HY-101399
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H-γ-Glu-Phe-OH; γ-Glutamylphenylalanine
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Endogenous Metabolite
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Others
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γ-Glu-Phe is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
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- HY-136149
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SARS-CoV
Virus Protease
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Infection
|
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Mpro inhibitor N3 is a potent SARS-CoV-2 MPro inhibitor with an EC50 value of 16.77 µM. Mpro inhibitor N3 shows antiviral activities against HCoV-229E, FIPV, IBV and MHV-A59 .
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- HY-B2162D
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Chondroitin polysulfate (from chicken)
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ERK
p38 MAPK
Interleukin Related
TNF Receptor
Prostaglandin Receptor
MMP
Endogenous Metabolite
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Inflammation/Immunology
|
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Chondroitin sulfate (from chicken) (Chondroitin polysulfate (from chicken)) is an orally active, sulfated linear polysaccharide extracted from chickens, which belongs to glycosaminoglycans. Chondroitin sulfate (from chicken) reduces the phosphorylation levels of ERK1/2 and p38MAPK, inhibits the expression of inflammatory cytokines and MMP, and downregulates the levels of IL-1β, IL-6, TNF-α and PGE2. Chondroitin sulfate (from chicken) improves motor function, protects cartilage tissue, reverses chondrocyte aggregation, and regulates the structure of intestinal flora. Chondroitin sulfate (from chicken) can be used in research related to osteoarthritis .
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- HY-P4279
-
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Angiotensin-converting Enzyme (ACE)
Cholinesterase (ChE)
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Cardiovascular Disease
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Ovalbumin (154-159) is a protein fragment consisting of residues 154-159 of chicken ovalbumin. Ovalbumin (154-159) is also a poorly conserved sequence (Thr-Asn-Gly-Ile-Ile-Arg) in the α-subunit of the Torpedo acetylcholine receptor, located within the α150-164 epitope region, and exhibits significant angiotensin-converting enzyme (ACE) inhibitory activity .
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- HY-B1088
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- HY-B1337S
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Cholinesterase (ChE)
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Others
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Choline-d4 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
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- HY-12361
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Parasite
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Infection
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PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research .
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- HY-N7071A
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Maduramycin ammonium
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Bacterial
Apoptosis
Antibiotic
Autophagy
AMPK
Eukaryotic Initiation Factor (eIF)
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Infection
Cardiovascular Disease
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Maduramicin ammonium (Maduramycin ammonium) is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection . Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways .
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- HY-121075
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Fluorescent Dye
Reverse Transcriptase
HIV
RSV
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Infection
Endocrinology
Cancer
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Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens .
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- HY-107814
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-
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- HY-W016618
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Ethyl benzoylformate; Phenylglyoxylic acid ethyl ester
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Drug Intermediate
Biochemical Assay Reagents
Carboxylesterase (CES)
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Others
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Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .
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- HY-N6726
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|
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Fungal
Endogenous Metabolite
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Infection
Cancer
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Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma .
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- HY-NP005
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Biochemical Assay Reagents
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Inflammation/Immunology
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Avidin, chicken egg white is a glycoprotein derived from egg protein. Avidin, chicken egg white has excellent affinity with biotin and is often used in combination with biotin for immunoassays to detect the location of antigens in tissues .
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- HY-128371
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Biochemical Assay Reagents
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Others
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2-Methylhexanoic acid is a saturated branched-chain carboxylic acid with a strong "fatty" or "oily" odor. At high concentrations, it is often described as having the smell of lard, chicken fat or sweat; when diluted, it exhibits a dairy, cream or cheese aroma. Therefore, it is commonly used in the formulation of milk, meat (pork/chicken) and baked food flavors. 2-Methylhexanoic acid occurs naturally in fresh apples, cheese, grape brandy, lamb, potatoes and tea .
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- HY-B1337S3
-
|
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Isotope-Labeled Compounds
Endogenous Metabolite
Cholinesterase (ChE)
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Others
|
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Choline-d13 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
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- HY-B1337S4
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Cholinesterase (ChE)
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Others
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Choline Chloride- 13C3 is the 13C-labeled Choline (chloride). Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
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- HY-NP134
-
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Toll-like Receptor (TLR)
MyD88
NF-κB
Interleukin Related
IFNAR
|
Inflammation/Immunology
Cancer
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Flagellin from S. typhimurium is a potent TLR5 agonist. Flagellin from S. typhimurium activates immune cells and inhibits the activity of melanoma cells. Flagellin from S. typhimurium activates the NF-κB pathway dependent on the TLR5/MyD88/TRAF6 signaling axis in cells. Flagellin from S. typhimurium induces a proinflammatory response in the primary chicken hepatocyte-nonparenchymal cell co-culture system by promoting IL-8 production, inhibiting IL-10 production, and increasing the IFN-γ/IL-10 ratio. Flagellin from S. typhimurium can be used for research on melanoma and inflammatory diseases .
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- HY-B1094
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2-Chloro-4-nitrobenzamide
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Environmental Pollutants
Parasite
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Infection
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Aklomide (2-Chloro-4-nitrobenzamide) is a coccidiostat agent. Aklomide can be used for the prevention and control of coccidiosis in chickens .
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- HY-N12540
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MGDG
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DNA/RNA Synthesis
Apoptosis
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Others
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Monogalactosyldiacylglycerol (MGDG) is a galactolipid with anti-inflammatory and anticancer activities, which is found in photosynthetic organisms. Monogalactosyldiacylglycerol is a potent DNA polymerase inhibitor with pro-apoptotic activity. Monogalactosyldiacylglycerol inhibits the synthesis of LPS (HY-D1056)-induced inflammation-related proteins (Ex-FABP, Avidin, Serum Amyloid A). Monogalactosyldiacylglycerol exerts an anti-proliferative effect on chicken articular chondrocytes . Monogalactosyldiacylglycerol can be used in research related to osteoarthritis, cancer and inflammatory diseases .
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- HY-P2818B
-
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Apase, Chicken Intestine
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Endogenous Metabolite
Phosphatase
Glutathione Peroxidase
Bacterial
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Infection
Inflammation/Immunology
|
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Alkaline Phosphatase (Apase), Chicken Intestine is an alkaline phosphatase from Chicken Intestine, and is one of the most active alkaline phosphatases. Alkaline phosphatase, Chicken Intestine is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Chicken Intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Chicken Intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Chicken Intestine improves TNBS-induced colon inflammation .
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- HY-107814S
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Parasite
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Infection
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Nicarbazin-d8 is deuterium labeled Nicarbazin. Nicarbazin is an effective anticoccidial agent for chickens .
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- HY-B2138
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Ethyl pabate
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Parasite
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Infection
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Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases .
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- HY-N8492
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Bacterial
Calcium Channel
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Infection
Inflammation/Immunology
Cancer
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Monascorubrin is a compound that can be isolated from Monascus mycelia. Monascorubrin has activities such as anti-inflammatory, anti-tumor, antibacterial, and immunomodulatory. Monascorubrin also has certain embryotoxicity, with an ED50 of 4.3 μg for chicken embryos. Monascorubrin can be used for the research of tumors and inflammatory diseases .
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- HY-B1205R
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Tropine tropate (Standard); DL-Hyoscyamine (Standard)
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Reference Standards
mAChR
Endogenous Metabolite
|
Cardiovascular Disease
Neurological Disease
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|
Atropine (Standard) is the analytical standard of Atropine. This product is intended for research and analytical applications. Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia .
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- HY-125953
-
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Ceramide (Egg, Chicken)
|
JNK
p38 MAPK
Phosphatase
Akt
Survivin
CDK
mTOR
Apoptosis
Autophagy
Reactive Oxygen Species (ROS)
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Neurological Disease
Cancer
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Ceramide (Egg) (Ceramide (Egg, Chicken)) is a ceramide from chicken. Ceramide (Egg) is a sphingomyelin signaling pathway second messenger. Ceramide (Egg) activates PP2A, JNK, p38 MAPK, CAPK, ceramide-activated protein phosphatase, Vav, PKCζ, and SAPK/JNK cascade. Ceramide (Egg) downregulates or inhibits AKT, survivin, CDK2, mTOR, and FLIP. Ceramide (Egg) mediates apoptosis, autophagy, cell cycle arrest, mitochondrial dysfunction, redox state shifts, and ROS generation. Ceramide (Egg) can be used for the research of cancer and neurological disease .
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- HY-120997
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Berbamine p-nitrobenzoate
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Calmodulin
Myosin
Phosphodiesterase (PDE)
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Cardiovascular Disease
Cancer
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E6 Berbamine (Berbamine p-nitrobenzoate) is a potent calmodulin (CaM) antagonist. E6 Berbamine inhibits the activities of calmodulin-dependent myosin light chain kinase (MLCK) and phosphodiesterase (PDE). E6 Berbamine exhibits anti-leukemic activity. E6 Berbamine can be used in research related to cardiovascular abnormalities and chronic myeloid leukemia .
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- HY-NP0218
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-
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- HY-N6726S
-
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Isotope-Labeled Compounds
Fungal
Endogenous Metabolite
|
Infection
Cancer
|
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Fumonisin B3- 13C34 is the 13C labeled Fumonisin B3 (HY-N6726). Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma .
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- HY-P2807G
-
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LAD, LD, L-LDH, (S)-Lactate, LDH
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Lactate Dehydrogenase
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Others
|
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Lactate Dehydrogenase (LDH), Chicken Heart (LAD, LD, L-LDH, (S)-Lactate, LDH) is a biological material or organic compound that can be used in life science research .
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-
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- HY-N12201
-
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Antibiotic
Fungal
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Infection
|
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Funiculosin is a neutral lipophilic antibiotic that inhibits DNA and RNA viruses. Funiculosin also has antifungal activity. Funiculosin inhibits infections caused by pathogenic fungi in primary chicken embryo fibroblasts .
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-
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- HY-161681
-
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Guanylate Cyclase
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Metabolic Disease
|
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Formycin triphosphate is a fluorescent analogue of ATP which on binding to enzyme active sites exhibits enhanced fluorescence. Formycin triphosphate is an ATP-competitive chicken liver pyruvate carboxylase inhibitor. Formycin triphosphate potentiates atrial natriuretic factor (ANF)-stimulated guanylate cyclase activity with an EC50 at about 90 μM and inhibits ATP-stimulated guanylate cyclase activity with an IC50 at about 100 μM .
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-
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- HY-112095
-
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ENS-101 free base
|
iGluR
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Neurological Disease
|
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EVT-101 free base is a GluN2B antagonist. EVT-101 free base binds at the same GluN1/GluN2B dimer interface as Ifenprodil (HY-12882). EVT-101 free base inhibits calcium influx in chicken-derived cells, with an EC50 of 22 nM. EVT-101 can be used in the research of brain disorders .
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-
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- HY-B1205AR
-
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Tropine tropate sulfate (Standard); DL-Hyoscyamine sulfate (Standard); Sulfatropinol (Standard)
|
Reference Standards
mAChR
|
Cardiovascular Disease
Neurological Disease
|
|
Atropine (sulfate) (Standard) is the analytical standard of Atropine (sulfate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .
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-
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- HY-116021
-
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Parasite
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Infection
|
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Buquinolate is a quinoline derivative. Buquinolate is effective in preventing coccidiosis of chickens .
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- HY-NP0208
-
-
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- HY-NP0220
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-
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- HY-P1905
-
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GnRH Receptor
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Endocrinology
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[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.
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-
![[Gln8]-C517 (LH-RH), chicken](//file.medchemexpress.com/product_pic/hy-p1905.gif)
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- HY-N15389
-
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Influenza Virus
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Infection
|
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Noformicin has inhibitory effect on mumps virus and Newcastle disease virus in chicken embryo. Noformicin also extended the survival of mice infected with swine, influenza A (PR8) and influenza B (Lee) viruses .
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- HY-N7071
-
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Maduramycin
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Antibiotic
Apoptosis
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Infection
|
|
Maduramicin (Maduramycin) is isolated from the actinomycete Actinomadura rubra. Maduramicin is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection . Maduramicin induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways .
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- HY-125153
-
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Influenza Virus
|
Others
|
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Bursin is a peptide that can be isolated from the bursa of Fabricius of chicken. Bursin induces the phenotypic differentiation of mammalian and avian B precursor cells. Bursin also increases cyclic guanosine monophosphate in cells of the human B-cell line Daudi, its derivatives are able to protect against infection by amplifying the immune response induced by H9N2 .
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- HY-N6720
-
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Endogenous Metabolite
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Metabolic Disease
|
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T-2 Triol is a trichothecene mycotoxin derived by the metabolism of T-2 toxin. It is less toxic than T-2 toxin . T-2 Triol major metabolites are evaluated in broiler chickens with Half-lives (t1/2λz), Peak plasma concentrations (Cmax) and Tmax values of 9.6 mins, 563 ng/ml , 2.5 mins, respectively .
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- HY-107814R
-
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Reference Standards
Parasite
|
Infection
|
|
Nicarbazin (Standard) is the analytical standard of Nicarbazin. This product is intended for research and analytical applications. Nicarbazin is an effective anticoccidial agent for chickens .
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- HY-23193
-
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Influenza Virus
|
Infection
|
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BMS-199945 is a influenza virus fusion inhibitor with the IC50 values of 0.57 μM and approximately 1 μM aganist influenza A/WSN/33 virus-induced hemolysis of chicken RBC and in the trypsin protection assay, respectively .
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- HY-P10160
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chCATH-2
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Bacterial
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Infection
|
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Cathelicidin-2 chicken is antimicrobial peptide. Cathelicidin-2 chicken shows potent bactericidal and fungicidal activity against chicken-specific salmonella isolates .
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- HY-P3604
-
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Androgen Receptor
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Endocrinology
|
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LH-RH II (chicken) is one of the two forms of luteinizing hormone-releasing hormone (LHRH) the hypothalamus of the domestic hen, which are structural variants of mammalian LHRH. LH-RH II (chicken) enhances gonadotrophin release in the domestic chicken .
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- HY-P10237
-
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Calcium Channel
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Others
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Calcitonin chicken is a hormone, that regulates calcium metabolism. Calcitonin chicken suppresses the cell motility and bone resorption in neonatal rat osteoclasts .
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- HY-113601
-
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Bacterial
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Others
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Linatine is an antagonist for Vitamin B6 (HY-150525). Linatine inhibits the growth of chicken and Azotobacter vinelandii, induces vitamin B6 deficiency symptoms in chickens .
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- HY-NP0215
-
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Biochemical Assay Reagents
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Others
|
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Chicken Serum Albumin is a plasma protein derived from chicken. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .
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- HY-P1560
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Lysozyme C (46-61) (chicken)
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Bacterial
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Infection
|
|
Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.
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- HY-P3583
-
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GnRH Receptor
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Others
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Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) is an active petide. (Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) can be used for the research of various biochemical studies .
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- HY-B1148A
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Altafur
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Bacterial
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Infection
|
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Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .
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- HY-N14868
-
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Others
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Neurological Disease
|
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Neuroprotectin B is a cyclopeptide. Neuroprotectin B has the function of protecting chicken brain neuron culture from excitatory toxicity induced by glutamate and red alginate .
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- HY-B1148B
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Altafur L-tartrate
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Bacterial
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Infection
Inflammation/Immunology
|
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Furaltadone L-tartrate (Altafur L-tartrate), a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .
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- HY-N6726R
-
|
|
Reference Standards
Fungal
Endogenous Metabolite
|
Infection
Cancer
|
|
Fumonisin B3 (Standard) is the analytical standard of Fumonisin B3. This product is intended for research and analytical applications. Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma .
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- HY-P2719
-
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Integrin
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Neurological Disease
|
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Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide that is responsible for melanoma cell adhesion, and plays an important role in development of the peripheral nervous system in chicken .
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- HY-N14067
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- HY-120690
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|
|
Influenza Virus
|
Infection
|
|
RO5464466 is an hemagglutinin (HA) inhibitor of influenza H1N1 viruses. RO5464466 inhibits HA-mediated hemolysis of chicken erythrocytes with the IC50 of 0.29 μM .
|
-
- HY-N6726S1
-
|
|
Isotope-Labeled Compounds
Fungal
Endogenous Metabolite
|
Infection
Cancer
|
|
Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma .
|
-
- HY-B1148AR
-
|
Altafur (Standard)
|
Reference Standards
Bacterial
|
Infection
|
|
Furaltadone (Standard) is the analytical standard of Furaltadone. This product is intended for research and analytical applications. Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .
|
-
- HY-B1148R
-
|
Altafur hydrochloride (Standard)
|
Reference Standards
Bacterial
|
Inflammation/Immunology
|
|
Furaltadone (hydrochloride) (Standard) is the analytical standard of Furaltadone (hydrochloride). This product is intended for research and analytical applications. Furaltadone hydrochloride, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .
|
-
- HY-121399
-
|
|
Histamine Receptor
|
Neurological Disease
|
|
Gizzerosine is an H2 receptor agonist. It can stimulate the gastric acid secretion of broiler chickens, thus causing gizzard erosion in them. Gizzerosine has significant research value in the fields of agricultural farming and feed science .
|
-
- HY-B1337S2
-
|
|
Endogenous Metabolite
|
Others
|
|
Choline-d6 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
|
-
- HY-B1148AS
-
|
Altafur-d5
|
Bacterial
Isotope-Labeled Compounds
|
Others
|
|
Furaltadone-d5 is the deuterium labeled Furaltadone (HY-B1148A). Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .
|
-
- HY-B0278R
-
|
Zinc bacitracin (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Bacitracin Zinc (Standard) is the analytical standard of Bacitracin Zinc (HY-B0278). Bacitracin Zinc (Standard) is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc (Standard) is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc (Standard) can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle .
|
-
- HY-B1088R
-
|
WR-61112 (Standard)
|
Reference Standards
Parasite
Antibiotic
|
Infection
Cardiovascular Disease
|
|
Clopidol (Standard) is the analytical standard of Clopidol. This product is intended for research and analytical applications. Clopidol (WR-61112) is an anticoccidial agent which is used as feed additive to control coccidiosis in chickens. Clopidol inhibits the sporulation of Eimeria tenella oocysts .
|
-
- HY-125153A
-
|
|
Others
|
Endocrinology
|
|
Bursin triacetate is a peptide that can be isolated from the bursa of Fabricius in chickens. It promotes the phenotypic differentiation of B precursor cells in both mammals and birds. Bursin triacetate increases cyclic guanosine monophosphate levels in the human B-cell line Daudi .
|
-
- HY-101399A
-
|
H-γ-Glu-Phe-OH TFA; γ-Glutamylphenylalanine TFA
|
Endogenous Metabolite
|
Others
|
|
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
|
-
- HY-149088
-
|
|
Influenza Virus
|
Infection
|
|
Neuraminidase-IN-16 (Compound 43b) is a potent neuraminidase inhibitor with IC50s of 0.031, 0.15, 0.25, 0.60, 0.63 and 10.08 μM against neuraminidase of H5N1, H5N8, H1N1, H3N2, H5N1-H274Y and H1N1-H274Y, respectively .
|
-
- HY-101399S
-
|
H-γ-Glu-Phe-OH-13C9,15N; γ-Glutamylphenylalanine-13C9,15N
|
Isotope-Labeled Compounds
|
Others
|
|
γ-Glu-(Phe- 13C9, 15N) is the 13C and 15N labeled isotope of γ-Glu-Phe(HY-101399).γ-Glu-Phe or the postenzymatic reaction mixture enhanced the umami intensity of commercial soy sauce and model chicken soup.
|
-
- HY-144103
-
|
|
Influenza Virus
|
Infection
|
|
Neuraminidase-IN-4 (Compound 4b) is a potent inhibitor of neuraminidase with an EC50 of 1.59 μM. Neuraminidase (NA) is an important target for the research of influenza. Neuraminidase-IN-4 exhibits excellent antiviral activity against A/chicken/Hubei/327/2004 (H5N1-DW) .
|
-
- HY-B1205B
-
|
Tropine tropate hydrobromide; DL-Hyoscyamine hydrobromide
|
mAChR
|
Cardiovascular Disease
Neurological Disease
Cancer
|
|
Atropine (Tropine tropate) hydrobromide is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine hydrobromide inhibits ACh-induced relaxations in human pulmonary veins. Atropine hydrobromide can be used for research of anti-myopia and bradycardia .
|
-
- HY-N7071AR
-
|
Maduramycin ammonium (Standard)
|
Reference Standards
Bacterial
Apoptosis
Antibiotic
|
Infection
|
|
Maduramicin (ammonium) (Standard) is the analytical standard of Maduramicin (ammonium). This product is intended for research and analytical applications. Maduramicin ammonium (Maduramycin ammonium) is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection . Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways .
|
-
- HY-W016618R
-
|
Ethyl benzoylformate (Standard); Phenylglyoxylic acid ethyl ester (Standard)
|
Drug Intermediate
Reference Standards
Biochemical Assay Reagents
Carboxylesterase (CES)
|
Others
|
|
Ethyl phenylglyoxylate (Ethyl benzoylformate) (Standard) is the analytical standard of Ethyl phenylglyoxylate (HY-W016618). This product is intended for research and analytical applications. Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .
|
-
- HY-B0394R
-
|
Tropine tropate sulfate monohydrate (Standard); DL-Hyoscyamine sulfate monohydrate (Standard)
|
Reference Standards
mAChR
|
Cardiovascular Disease
Neurological Disease
|
|
Atropine (sulfate monohydrate) (Standard) is the analytical standard of Atropine (sulfate monohydrate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .
|
-
- HY-146001
-
|
|
Influenza Virus
|
Inflammation/Immunology
|
|
Influenza virus-IN-4 (compound 11e) is a potent influenza virus neuraminidase inhibitor with IC50s of 3.4, 0.094, 0.79, 0.077 µM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-4 shows NA (neuraminidase enzyme)-inhibitory activity. Influenza virus-IN-4 shows low cytotoxicity with an CC50 of >200 µM. Influenza virus-IN-4 shows no obvious toxicity at the dose of 1500 mg/kg in mice .
|
-
- HY-146000
-
|
|
Influenza Virus
|
Inflammation/Immunology
|
|
Influenza virus-IN-3 (compound 9) is a potent and selective influenza virus inhibitor with IC50s of 0.88, 0.10, 5.5, 0.51 µM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-3 shows antiviral and NA (neuraminidase enzyme)-inhibitory activity. Influenza virus-IN-3 shows low cytotoxicity with an CC50 of >200 µM .
|
-
- HY-183532
-
|
|
Parasite
|
Infection
|
|
Anticoccidial agent-2 is an orally effective imidazole-based anticoccidial agent. Anticoccidial agent-2 exhibits activity against Eimeria tenella in chickens. Anticoccidial agent-2 can be used in research related to chicken cecal coccidiosis .
|
-
- HY-NP185
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Chicken Tenascin,suitable for cell culture is a glycoprotein that forms disulfide-linked hexamers. Chicken Tenascin,suitable for cell culture is composed of repetitive domains, including EGF-like repeats, fibronectin type III repeats, and a region homologous to fibrinogen. Chicken Tenascin,suitable for cell culture can be used for cell culture .
|
-
- HY-114625
-
|
|
Parasite
Mitochondrial Metabolism
|
Infection
|
|
Amquinate is a coccidiostat and a cytochrome b inhibitor. Amquinate blocks cytochrome-mediated electron transport near cytochrome b in mitochondria, acting downstream of coenzyme Q without affecting succinate dehydrogenase or NADH dehydrogenase. Amquinate inhibits succinate- and malate plus pyruvate-supported mitochondrial respiration in Eimeria tenella and does not affect L-ascorbate-supported respiration or any mitochondrial respiration in chicken liver mitochondria. Amquinate exhibits selective anticoccidial activity against wild-type Eimeria tenella. Amquinate can be used for the research of coccidiosis (Eimeria tenella infection) .
|
-
- HY-P2952C
-
-
- HY-P2820C
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Phosphoglucomutase, Chicken (EC 5.4.2.2) is an enzyme that transfers a phosphate group on an α-D-glucose monomer from the 1' to the 6' position in the forward direction or the 6' to the 1' position in the reverse direction. Phosphoglucomutase, Chicken (EC 5.4.2.2) facilitates the interconversion of glucose 1-phosphate and glucose 6-phosphate.
|
-
- HY-E70963A
-
-
- HY-P2765C
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Glyceraldehyde-3-phosphate Dehydrogenase, Chicken (EC 1.2.1.12) catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis.
|
-
- HY-E71019
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Sulfite Oxidase, Chicken (EC 1.8.3.1) oxidizes sulfite to sulfate and transfers the generated electrons to the electron transport chain via cytochrome c, thereby generating ATP during oxidative phosphorylation.
|
-
- HY-N14010
-
|
|
Bacterial
|
Infection
|
|
Cationomycin inhibits the activity of Gram-positive bacteria and mycobacterium, but has no effect on Gram-negative bacteria, yeast and fungi. The feed containing 50-100 ppm Cationomycin could effectively prevent coccidiosis of chicken .
|
-
- HY-P2809C
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Malic Dehydrogenase (oxaloacetate-decarboxylating), Chicken (EC 1.1.1.40) exists as two isoforms within eukaryotic cells, one that is expressed in the mitochondria and functions in the TCA cycle and one in the cytoplasm that converts malate from the mitochondria back into oxaloacetate.
|
-
- HY-108685R
-
|
Alendronic acid monosodium salt (Standard)
|
Reference Standards
NF-κB
Interleukin Related
|
Metabolic Disease
|
|
Alendronate sodium (Standard) is the analytical standard of Alendronate sodium (HY-108685). This product is intended for research and analytical applications. Alendronate sodium is an orally active bisphosphonate which binds to bone surfaces and inhibits bone resorption by osteoclasts. Alendronate sodium induces skeletal alterations in the chicken embryonic development model. Alendronate sodium can be used for osteoporosis research .
|
-
- HY-12361R
-
|
|
Reference Standards
Parasite
|
Infection
|
|
PF 1022A (Standard) is the analytical standard of PF 1022A. This product is intended for research and analytical applications. PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research[1][2][3].
|
-
- HY-W701476
-
|
Ethyl benzoylformate-d5; Phenylglyoxylic acid ethyl ester-d5
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
Drug Intermediate
Carboxylesterase (CES)
|
Others
|
|
Ethyl phenylglyoxylate-d5 (Ethyl benzoylformate-d5; Phenylglyoxylic acid ethyl ester-d5) is the deuterium labeled Ethyl phenylglyoxylate (HY-W016618). Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .
|
-
- HY-N10843
-
|
|
Influenza Virus
|
Infection
|
|
4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC50 values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively .
|
-
- HY-W320523
-
|
|
Fluorescent Dye
Reverse Transcriptase
HIV
RSV
|
Infection
Metabolic Disease
Cancer
|
|
ALizarin complexone dihydrate is the dehydrate of Alizarin complexone (HY-121075). Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens .
|
-
- HY-101399SA
-
|
H-γ-Glu-Phe-OH-13C9,15N TFA; γ-Glutamylphenylalanine-13C9,15N TFA
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
γ-Glu-(Phe-13C9,15N) (γ-Glutamylphenylalanine-13C9,15N) TFA is the 13C- and 15N-labeled γ-Glu-Phe TFA (HY-101399A). γ-Glu-Phe TFA is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
|
-
- HY-178921
-
|
|
Drug Derivative
Apoptosis
|
Cancer
|
HJ-4 is a Piperine (HY-N0144) derivative. HJ-4 potently inhibits the proliferation of CRC cells by dose-dependently reducing colony formation and DNA synthesis. HJ-4 markedly suppresses the adhesion, migration, invasion and induces apoptosis of CRC cells. HJ-4 demonstrates anti-tumor efficacy in chicken embryo chorioallantoic membrane (CAM) model implanted with HCT116/SW480 tumor spheroids. HJ-4 can be used for the study of colorectal cancer (CRC) .
|
-
- HY-121075R
-
|
|
Reference Standards
Reverse Transcriptase
Fluorescent Dye
HIV
RSV
|
Infection
Endocrinology
Cancer
|
|
Alizarin complexone (Standard) is the analytical standard of Alizarin complexone (HY-121075). This product is intended for research and analytical applications. Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens .
|
-
- HY-178453
-
|
|
VEGFR
Apoptosis
|
Cancer
|
|
VEGFR-2-IN-74 (compound 55) is a potent VEGFR-2 inhibitor (IC50 = 0.035 µM). VEGFR-2-IN-74 exhibits good anti proliferative activity and can induce apoptosis in various cancer cells, such as A549 (IC50 = 2.67 µM) and HCT116 (IC50 = 10.87 µM) cells. VEGFR-2-IN-74 has low toxicity to normal cells. VEGFR-2-IN-74 shows significant anti angiogenic effects in chicken embryo models. VEGFR-2-IN-74 can be used in the research of cancer .
|
-
- HY-182410
-
|
|
iGluR
|
Neurological Disease
|
|
EGIS-9637 is a non-competitive AMPA antagonist and acylated dihydro-2,3-benzodiazepine class member .
|
-
- HY-N18431
-
|
ST-A TFA
|
Fungal
|
Infection
|
|
Stellettamide A TFA is a marine toxin found in a marine sponge. Stellettamide A TFA is a calmodulin inhibitor. Stellettamide A TFA can inhibit Ca 2+/Mg 2+ ATPase, phosphodiesterase, myosin light chain , and Mg 2+-ATPase. Stellettamide A TFA inhibits high K +- and Ca 2+-induced contraction in permeabilized smooth muscle. Stellettamide A TFA exhibits antifungal activity against Mortierella remannianus. Stellettamide A TFA can be used for the research of fungal infection .
|
-
- HY-W008150
-
|
α-Hydroxyisovaleric acid
|
Endogenous Metabolite
|
Metabolic Disease
|
|
2-Hydroxy-3-methylbutanoic acid (α-Hydroxyisovaleric acid) is an α-hydroxy analogue of valine and a valine precursor that reduces urea excretion. 2-Hydroxy-3-methylbutanoic acid can promote the growth of chickens and rats, and is converted into valine in the body, participating in protein synthesis and maintaining nitrogen balance, thereby supporting animal growth and development. 2-Hydroxy-3-methylbutanoic acid has a more significant effect on the valine-deficient dietary model. 2-Hydroxy-3-methylbutanoic acid is mainly used in animal nutrition research to evaluate its potential application as a nitrogen source substitute in feed .
|
-
- HY-N7000
-
-
- HY-180814
-
|
|
Drug Derivative
Dopamine Receptor
|
Cancer
|
|
SKF-83566-PEG1-pomalidomide is an anti-tumor agent and is formed by the covalent connection of SKF-83566 (HY-103430A) (dopamine D1 receptor antagonist) and Pomalidomide (HY-10984) (immunomodulatory agent). SKF-83566-PEG1-pomalidomide can inhibit cancer cells invasion, migration and colony formation. SKF-83566-PEG1-pomalidomide can inhibit tumor growth and angiogenesis in MDA-MB-231 cell chicken embryo chorioallantoic membrane (CAM) xenograft model. SKF-83566-PEG1-pomalidomide can be used for research of breast cancer .
|
-
- HY-W088066
-
|
|
Bacterial
|
Infection
|
|
Trisodium phosphate dodecahydrate is an Antibacterial agent. Trisodium phosphate dodecahydrate reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate is used in poultry processing .
|
-
- HY-165391
-
|
|
Drug Derivative
|
Neurological Disease
|
|
NA0359 is a derivative of SF2370 (HY-N6732). NA0359 inhibits the actin-myosin-ATP interaction in native smooth muscle actomyosin and myosin light chain phosphorylation .
|
-
- HY-NP188
-
|
LEL (FITC)
|
Fluorescent Dye
Biochemical Assay Reagents
|
Others
|
|
Lycopersicon esculentum (Tomato) Lectin (FITC) is Lycopersicon esculentum (Tomato) Lectin (HY-NP071) labeled with FITC (HY-66019). Lycopersicon esculentum (Tomato) Lectin (FITC) binds to poly-N-acetyllactosamine oligosaccharides. Lycopersicon esculentum (Tomato) Lectin (FITC) is a major component of carbohydrates on the surface of endothelial and epithelial cells .
|
-
- HY-P992372
-
|
|
Drug Derivative
Transmembrane Glycoprotein
|
Cancer
|
|
huAA98 is a humanized monoclonal antibody and also a CD146 inhibitor. huAA98 binds to human CD146, regulates its activity and inhibits cancer-related angiogenesis, as well as tube formation, motility, proliferation and migration of endothelial cells. huAA98 inhibits angiogenesis in the chick chorioallantoic membrane assay and reduces microvessel density in human tumor xenograft models. huAA98 shows immunoreactivity only to neovascular vessels within tumors and inhibits the growth of tumor xenograft models. huAA98 can be used in studies related to cancer-related angiogenesis, liver cancer, leiomyosarcoma and pancreatic cancer .
|
-
- HY-W008150R
-
|
α-Hydroxyisovaleric acid (Standard)
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
|
2-Hydroxy-3-methylbutanoic acid (α-Hydroxyisovaleric acid) (Standard) is the analytical standard of 2-Hydroxy-3-methylbutanoic acid (HY-W008150). This product is intended for research and analytical applications. 2-Hydroxy-3-methylbutanoic acid is an α-hydroxy analogue of valine and a valine precursor that reduces urea excretion. 2-Hydroxy-3-methylbutanoic acid can promote the growth of chickens and rats, and is converted into valine in the body, participating in protein synthesis and maintaining nitrogen balance, thereby supporting animal growth and development. 2-Hydroxy-3-methylbutanoic acid has a more significant effect on the valine-deficient dietary model. 2-Hydroxy-3-methylbutanoic acid is mainly used in animal nutrition research to evaluate its potential application as a nitrogen source substitute in feed.
|
-
- HY-W725504
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
2-Hydroxy-3-methylbutanoic acid-d7 is the deuterium labeled 2-Hydroxy-3-methylbutanoic acid (HY-W008150). 2-Hydroxy-3-methylbutanoic acid is an α-hydroxy analogue of valine and a valine precursor that reduces urea excretion. 2-Hydroxy-3-methylbutanoic acid can promote the growth of chickens and rats, and is converted into valine in the body, participating in protein synthesis and maintaining nitrogen balance, thereby supporting animal growth and development. 2-Hydroxy-3-methylbutanoic acid has a more significant effect on the valine-deficient dietary model. 2-Hydroxy-3-methylbutanoic acid is mainly used in animal nutrition research to evaluate its potential application as a nitrogen source substitute in feed .
|
-
- HY-P3302
-
|
|
Bacterial
|
Infection
|
|
Sialylglycopeptide is an orally active glycopeptide found in egg yolk. Sialylglycopeptide inhibits the binding of Salmonella enteritidis and Escherichia coli to intestinal cells, and protects mice from Salmonella infection. Sialylglycopeptide can be used in the research of Salmonella infection .
|
-
- HY-182477
-
|
|
Antibiotic
Bacterial
Fungal
|
Infection
|
|
Siccayne, found in the marine basidiomycete Halocyphina villosa and deuteromycete Helminthosporium siccans, is an antibiotic. Siccayne interferes with nucleotide incorporation into DNA and RNA, precursor transport enzymatic reactions, and essential macromolecule synthesis. Siccayne inhibits Gram-positive bacteria and some fungi. Siccayne can be used for research on infections caused by bacteria and fungi .
|
-
- HY-172166B
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
TRITC-lysine-dextran (MW 70kDa) is a fluorescent label prepared by the conjugation of TRITC (HY-D0791), lysine and dextran. TRITC-lysine-dextran (MW 70kDa) serves multiple functions as an axonal tracer, non-viral nanocarrier and fixable fluorescent clonal marker. TRITC-lysine-dextran (MW 70kDa) undergoes anterograde and retrograde transport within axons of sensory neurons, and acts as a non-viral delivery system to precisely deliver biomolecules to neurons. TRITC-lysine-dextran (MW 70kDa) remains stably retained during histological preparation, thereby supporting continuous observation in live or fixed samples .
|
-
- HY-D0877
-
|
|
Biochemical Assay Reagents
Connexin
|
Others
|
|
TAPS is an aminosulfonate-based lysozyme stabilizer and connexin channel inhibitor. TAPS maintains the native structure of lysozyme in aqueous solution at pH 7.0 and significantly protects it from heat-induced denaturation. TAPS directly inhibits the activity of heteromeric connexin 32/connexin 26 channels (Cx32/Cx26) via its protonated form, and this inhibitory effect is dependent on the presence of connexin 26. TAPS reduces connexin channel-mediated solute exchange in a recombinant liposome system, resulting in a decreased degree of liposome density shift in transport-specific separation assays. TAPS is a critical compound for investigating the structure and function of connexin channels .
|
-
- HY-150520
-
|
|
Antibiotic
Phospholipase
|
Infection
Cancer
|
|
Neomycin, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin is a known phospholipase C (PLC) inhibitor. Neomycin potently inhibits both the nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis. Neomycin inhibits IP3-mediated Ca 2+ release, MgATP-dependent Ca 2+ uptake, and electrical excitation-evoked skeletal muscle Ca 2+ transients. Neomycin depletes gut microbiota in specific mouse models, causes hearing impairment, and kidney damage with prolonged exposure. Neomycin can be used for the research of cancer .
|
-
- HY-N0260
-
|
Epimedin-C; Baohuoside-VI
|
Keap1-Nrf2
CDK
Caspase
|
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Epmedin C (Epimedin-C; Baohuoside-VI) is an orally active anti-inflammatory agent and immunomodulator that binds to multiple key proteins including UCP1, Caspase-1, CDK2 and Keap1. Epmedin C inhibits epithelial cell proliferation by disrupting the complex function of CDK2/Cyclin E. Epmedin C also upregulates Nrf2 expression, reduces ROS levels and inhibits pro-inflammatory cytokine secretion, thereby effectively restoring antibody production and alleviating tissue damage. Epmedin C has good safety with no hepatotoxicity or skin sensitization, and it has been used in studies on diseases such as obesity, Deoxynivalenol (HY-N6684)-induced immunotoxicity and mammary hyperplasia .
|
-
- HY-B0470
-
|
|
Environmental Pollutants
Antibiotic
Phospholipase
Bacterial
|
Infection
Metabolic Disease
Cancer
|
|
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both the nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis. Neomycin sulfate inhibits IP3-mediated Ca 2+ release, MgATP-dependent Ca 2+ uptake, and electrical excitation-evoked skeletal muscle Ca 2+ transients. Neomycin sulfate depletes gut microbiota in specific mouse models, causes hearing impairment, and kidney damage with prolonged exposure. Neomycin sulfate can be used for the research of cancer .
|
-
- HY-W021448
-
|
Guanidinoacetic acid
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Glycocyamine (Guanidinoacetic acid) is a direct precursor of creatine and an orally active energy metabolism regulator and myogenic differentiation inducer. Glycocyamine can activate the Akt/mTOR/S6K signaling pathway via miR-133a-3p and miR-1a-3p, and stimulate the mRNA expression of myogenic differentiation factor 1 (MyoD) and myopoietin (MyoG). Glycocyamine can increase muscle creatine concentration and maintain ATP homeostasis through the creatine phosphate/creatine kinase system. Glycocyamine can be used in research on feed additives for poultry farming .
|
-
- HY-W011117
-
|
|
Bacterial
DNA/RNA Synthesis
Antibiotic
|
Infection
|
|
Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens .
|
-
- HY-B0570
-
|
|
nAChR
|
Neurological Disease
|
Decamethonium Bromide is an acetylcholine receptor inhibitor and muscle relaxant. Decamethonium Bromide first induces depolarization of skeletal muscles, and then binds to postsynaptic acetylcholine receptors to induce persistent paralysis .\n
|
-
- HY-P1408
-
|
|
Integrin
VEGFR
|
Cancer
|
|
Obtustatin is a non-RGD disintegrin consisting of 41 residues. Obtustatin inhibits the adhesion of α1β1 integrin to type IV Collagen (HY-NP003), blocks α1β1 integrin signaling in endothelial cells, and suppresses FGF2-induced angiogenesis. Obtustatin inhibits tumor progression in mouse models and upregulates VEGF expression in sarcoma-bearing mice. Obtustatin can be used in research related to Lewis lung carcinoma and S-180 sarcoma .
|
-
- HY-183929
-
|
|
Influenza Virus
|
Infection
|
|
Antiviral agent 87 is a potent antiviral agent with low cytotoxicity in host cells. Antiviral agent 87 stabilizes prefusion HA conformation, blocks viral membrane fusion and host cell entry, and inhibits entry and replication of diverse influenza A virus subtypes. Antiviral agent 87 can be used for the research of influenza A virus infection .
|
-
- HY-159201
-
|
|
Calcium Channel
|
Metabolic Disease
|
|
24-Oxo-25-hydroxyvitamin D3 is a vitamin D3 metabolite and an intermediate in the renal mitochondrial side-chain oxidation pathway. 24-Oxo-25-hydroxyvitamin D3 enhances intestinal calcium transport in rats . 24-Oxo-25-hydroxyvitamin D3 can be used in studies related to X-linked hypophosphatemic rickets .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-P2232
-
|
Ovotransferrin
|
Biochemical Assay Reagents
|
|
Conalbumin (Ovotransferrin) is an iron-binding protein present in egg white with antibacterial activity. Conalbumin can also be used to induce bronchial asthma. Conalbumin exhibits induced mRNA accumulation in chicken oviduct cells by estrogen and progesterone .
|
-
- HY-D0877
-
|
|
Biochemical Assay Reagents
|
|
TAPS is an aminosulfonate-based lysozyme stabilizer and connexin channel inhibitor. TAPS maintains the native structure of lysozyme in aqueous solution at pH 7.0 and significantly protects it from heat-induced denaturation. TAPS directly inhibits the activity of heteromeric connexin 32/connexin 26 channels (Cx32/Cx26) via its protonated form, and this inhibitory effect is dependent on the presence of connexin 26. TAPS reduces connexin channel-mediated solute exchange in a recombinant liposome system, resulting in a decreased degree of liposome density shift in transport-specific separation assays. TAPS is a critical compound for investigating the structure and function of connexin channels .
|
-
- HY-B2162D
-
|
Chondroitin polysulfate (from chicken)
|
Biochemical Assay Reagents
|
|
Chondroitin sulfate (from chicken) (Chondroitin polysulfate (from chicken)) is an orally active, sulfated linear polysaccharide extracted from chickens, which belongs to glycosaminoglycans. Chondroitin sulfate (from chicken) reduces the phosphorylation levels of ERK1/2 and p38MAPK, inhibits the expression of inflammatory cytokines and MMP, and downregulates the levels of IL-1β, IL-6, TNF-α and PGE2. Chondroitin sulfate (from chicken) improves motor function, protects cartilage tissue, reverses chondrocyte aggregation, and regulates the structure of intestinal flora. Chondroitin sulfate (from chicken) can be used in research related to osteoarthritis .
|
-
- HY-NP005
-
|
|
Biochemical Assay Reagents
|
|
Avidin, chicken egg white is a glycoprotein derived from egg protein. Avidin, chicken egg white has excellent affinity with biotin and is often used in combination with biotin for immunoassays to detect the location of antigens in tissues .
|
-
- HY-NP134
-
|
|
Biochemical Assay Reagents
|
|
Flagellin from S. typhimurium is a potent TLR5 agonist. Flagellin from S. typhimurium activates immune cells and inhibits the activity of melanoma cells. Flagellin from S. typhimurium activates the NF-κB pathway dependent on the TLR5/MyD88/TRAF6 signaling axis in cells. Flagellin from S. typhimurium induces a proinflammatory response in the primary chicken hepatocyte-nonparenchymal cell co-culture system by promoting IL-8 production, inhibiting IL-10 production, and increasing the IFN-γ/IL-10 ratio. Flagellin from S. typhimurium can be used for research on melanoma and inflammatory diseases .
|
-
- HY-NP188
-
|
LEL (FITC)
|
Biochemical Assay Reagents
|
|
Lycopersicon esculentum (Tomato) Lectin (FITC) is Lycopersicon esculentum (Tomato) Lectin (HY-NP071) labeled with FITC (HY-66019). Lycopersicon esculentum (Tomato) Lectin (FITC) binds to poly-N-acetyllactosamine oligosaccharides. Lycopersicon esculentum (Tomato) Lectin (FITC) is a major component of carbohydrates on the surface of endothelial and epithelial cells .
|
-
- HY-NP0218
-
|
|
Biochemical Assay Reagents
|
|
Chicken Ovomucoid is a major component of chicken ovalbumin, exhibiting trypsin inhibition and thermal stability .
|
-
- HY-NP0208
-
|
|
Biochemical Assay Reagents
|
|
Chicken Serum Transferrin is a major serum protein in chicken serum. Chicken Serum Transferrin is primarily responsible for transporting iron .
|
-
- HY-NP0220
-
|
|
Biochemical Assay Reagents
|
|
Chicken Yolk Immunoglobulin (IgY) is a natural antibody extracted from the yolk of immune hens. It has high stability and is widely used in antiviral, immunoassay and other fields .
|
-
- HY-NP0215
-
|
|
Biochemical Assay Reagents
|
|
Chicken Serum Albumin is a plasma protein derived from chicken. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .
|
-
- HY-W320523
-
|
|
Biochemical Assay Reagents
|
|
ALizarin complexone dihydrate is the dehydrate of Alizarin complexone (HY-121075). Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens .
|
-
- HY-172166B
-
|
|
Biochemical Assay Reagents
|
|
TRITC-lysine-dextran (MW 70kDa) is a fluorescent label prepared by the conjugation of TRITC (HY-D0791), lysine and dextran. TRITC-lysine-dextran (MW 70kDa) serves multiple functions as an axonal tracer, non-viral nanocarrier and fixable fluorescent clonal marker. TRITC-lysine-dextran (MW 70kDa) undergoes anterograde and retrograde transport within axons of sensory neurons, and acts as a non-viral delivery system to precisely deliver biomolecules to neurons. TRITC-lysine-dextran (MW 70kDa) remains stably retained during histological preparation, thereby supporting continuous observation in live or fixed samples .
|
-
- HY-NP185
-
|
|
Biochemical Assay Reagents
|
|
Chicken Tenascin,suitable for cell culture is a glycoprotein that forms disulfide-linked hexamers. Chicken Tenascin,suitable for cell culture is composed of repetitive domains, including EGF-like repeats, fibronectin type III repeats, and a region homologous to fibrinogen. Chicken Tenascin,suitable for cell culture can be used for cell culture .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-101399
-
|
H-γ-Glu-Phe-OH; γ-Glutamylphenylalanine
|
Endogenous Metabolite
|
Others
|
|
γ-Glu-Phe is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
|
-
- HY-P1408
-
|
|
Integrin
VEGFR
|
Cancer
|
|
Obtustatin is a non-RGD disintegrin consisting of 41 residues. Obtustatin inhibits the adhesion of α1β1 integrin to type IV Collagen (HY-NP003), blocks α1β1 integrin signaling in endothelial cells, and suppresses FGF2-induced angiogenesis. Obtustatin inhibits tumor progression in mouse models and upregulates VEGF expression in sarcoma-bearing mice. Obtustatin can be used in research related to Lewis lung carcinoma and S-180 sarcoma .
|
-
- HY-P4279
-
|
|
Angiotensin-converting Enzyme (ACE)
Cholinesterase (ChE)
|
Cardiovascular Disease
|
|
Ovalbumin (154-159) is a protein fragment consisting of residues 154-159 of chicken ovalbumin. Ovalbumin (154-159) is also a poorly conserved sequence (Thr-Asn-Gly-Ile-Ile-Arg) in the α-subunit of the Torpedo acetylcholine receptor, located within the α150-164 epitope region, and exhibits significant angiotensin-converting enzyme (ACE) inhibitory activity .
|
-
- HY-P3302
-
|
|
Bacterial
|
Infection
|
|
Sialylglycopeptide is an orally active glycopeptide found in egg yolk. Sialylglycopeptide inhibits the binding of Salmonella enteritidis and Escherichia coli to intestinal cells, and protects mice from Salmonella infection. Sialylglycopeptide can be used in the research of Salmonella infection .
|
-
- HY-P1905
-
|
|
GnRH Receptor
|
Endocrinology
|
|
[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.
|
-
- HY-125153
-
|
|
Influenza Virus
|
Others
|
|
Bursin is a peptide that can be isolated from the bursa of Fabricius of chicken. Bursin induces the phenotypic differentiation of mammalian and avian B precursor cells. Bursin also increases cyclic guanosine monophosphate in cells of the human B-cell line Daudi, its derivatives are able to protect against infection by amplifying the immune response induced by H9N2 .
|
-
- HY-P10160
-
|
chCATH-2
|
Bacterial
|
Infection
|
|
Cathelicidin-2 chicken is antimicrobial peptide. Cathelicidin-2 chicken shows potent bactericidal and fungicidal activity against chicken-specific salmonella isolates .
|
-
- HY-P3604
-
|
|
Androgen Receptor
|
Endocrinology
|
|
LH-RH II (chicken) is one of the two forms of luteinizing hormone-releasing hormone (LHRH) the hypothalamus of the domestic hen, which are structural variants of mammalian LHRH. LH-RH II (chicken) enhances gonadotrophin release in the domestic chicken .
|
-
- HY-P10237
-
|
|
Calcium Channel
|
Others
|
|
Calcitonin chicken is a hormone, that regulates calcium metabolism. Calcitonin chicken suppresses the cell motility and bone resorption in neonatal rat osteoclasts .
|
-
- HY-P1560
-
|
Lysozyme C (46-61) (chicken)
|
Bacterial
|
Infection
|
|
Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.
|
-
- HY-P3583
-
|
|
GnRH Receptor
|
Others
|
|
Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) is an active petide. (Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) can be used for the research of various biochemical studies .
|
-
- HY-P2719
-
|
|
Integrin
|
Neurological Disease
|
|
Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide that is responsible for melanoma cell adhesion, and plays an important role in development of the peripheral nervous system in chicken .
|
-
- HY-101399A
-
|
H-γ-Glu-Phe-OH TFA; γ-Glutamylphenylalanine TFA
|
Endogenous Metabolite
|
Others
|
|
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
|
-
- HY-P4801
-
|
Human PACAP(28-38)
|
Peptides
|
Others
|
|
PACAP-38 (28-38) (human, chicken, mouse, ovine, porcine, rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-K3030
-
|
|
|
Ham’s F-12K Medium was originally designed for the culture of primary human hepatocytes and differentiated rat and chicken cells. It is particularly suitable for single-cell cloning of Chinese hamster ovary (CHO) cells under serum-free conditions. When supplemented with serum, it can also be used for the culture of various other mammalian cell types, including chondrocytes and rat prostate epithelial cells.
|
| Cat. No. |
Product Name |
Target |
Research Area |
Image |
-
- HY-P992372
-
|
|
Drug Derivative
Transmembrane Glycoprotein
|
Cancer
|
|
huAA98 is a humanized monoclonal antibody and also a CD146 inhibitor. huAA98 binds to human CD146, regulates its activity and inhibits cancer-related angiogenesis, as well as tube formation, motility, proliferation and migration of endothelial cells. huAA98 inhibits angiogenesis in the chick chorioallantoic membrane assay and reduces microvessel density in human tumor xenograft models. huAA98 shows immunoreactivity only to neovascular vessels within tumors and inhibits the growth of tumor xenograft models. huAA98 can be used in studies related to cancer-related angiogenesis, liver cancer, leiomyosarcoma and pancreatic cancer .
|
-
(5)
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-B0470
-
-
-
- HY-B1205
-
-
-
- HY-B2237
-
-
-
- HY-W021448
-
-
-
- HY-N1500
-
-
-
- HY-W008150
-
-
-
- HY-N7000
-
-
-
- HY-N0260
-
-
-
- HY-W004307
-
-
-
- HY-101399
-
-
-
- HY-12361
-
-
-
- HY-N7071A
-
-
-
- HY-N6726
-
-
-
- HY-N12540
-
|
MGDG
|
Structural Classification
other families
Oplismenus burmannii
Plants
Lipid
Source Classification
|
DNA/RNA Synthesis
Apoptosis
|
|
Monogalactosyldiacylglycerol (MGDG) is a galactolipid with anti-inflammatory and anticancer activities, which is found in photosynthetic organisms. Monogalactosyldiacylglycerol is a potent DNA polymerase inhibitor with pro-apoptotic activity. Monogalactosyldiacylglycerol inhibits the synthesis of LPS (HY-D1056)-induced inflammation-related proteins (Ex-FABP, Avidin, Serum Amyloid A). Monogalactosyldiacylglycerol exerts an anti-proliferative effect on chicken articular chondrocytes . Monogalactosyldiacylglycerol can be used in research related to osteoarthritis, cancer and inflammatory diseases .
|
-
-
- HY-N8492
-
-
-
- HY-B1205R
-
|
Tropine tropate (Standard); DL-Hyoscyamine (Standard)
|
Atropa belladonna Linn.
Solanaceae
Plants
Endogenous metabolite
Source Classification
|
Reference Standards
mAChR
Endogenous Metabolite
|
|
Atropine (Standard) is the analytical standard of Atropine. This product is intended for research and analytical applications. Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia .
|
-
-
- HY-N12201
-
-
-
- HY-B1205AR
-
|
Tropine tropate sulfate (Standard); DL-Hyoscyamine sulfate (Standard); Sulfatropinol (Standard)
|
Alkaloids
Structural Classification
Other Alkaloids
Atropa belladonna Linn.
Solanaceae
Plants
Source Classification
|
Reference Standards
mAChR
|
|
Atropine (sulfate) (Standard) is the analytical standard of Atropine (sulfate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .
|
-
-
- HY-N10843
-
|
|
Flavanonols
Flavonoids
Caesalpiniaceae
Plants
Source Classification
|
Influenza Virus
|
|
4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC50 values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively .
|
-
-
- HY-W008150R
-
|
α-Hydroxyisovaleric acid (Standard)
|
Structural Classification
Ketones, Aldehydes, Acids
Disease markers
Endocrine diseases
Nervous System Disorder
Endogenous metabolite
Source Classification
|
Reference Standards
Endogenous Metabolite
|
|
2-Hydroxy-3-methylbutanoic acid (α-Hydroxyisovaleric acid) (Standard) is the analytical standard of 2-Hydroxy-3-methylbutanoic acid (HY-W008150). This product is intended for research and analytical applications. 2-Hydroxy-3-methylbutanoic acid is an α-hydroxy analogue of valine and a valine precursor that reduces urea excretion. 2-Hydroxy-3-methylbutanoic acid can promote the growth of chickens and rats, and is converted into valine in the body, participating in protein synthesis and maintaining nitrogen balance, thereby supporting animal growth and development. 2-Hydroxy-3-methylbutanoic acid has a more significant effect on the valine-deficient dietary model. 2-Hydroxy-3-methylbutanoic acid is mainly used in animal nutrition research to evaluate its potential application as a nitrogen source substitute in feed.
|
-
-
- HY-N15389
-
-
-
- HY-N7071
-
-
-
- HY-N6720
-
-
-
- HY-N14868
-
-
-
- HY-N6726R
-
-
-
- HY-N14067
-
-
-
- HY-101399A
-
-
-
- HY-N7071AR
-
|
Maduramycin ammonium (Standard)
|
Structural Classification
Microorganisms
Ketones, Aldehydes, Acids
Source Classification
|
Reference Standards
Bacterial
Apoptosis
Antibiotic
|
|
Maduramicin (ammonium) (Standard) is the analytical standard of Maduramicin (ammonium). This product is intended for research and analytical applications. Maduramicin ammonium (Maduramycin ammonium) is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection . Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways .
|
-
-
- HY-B0394R
-
|
Tropine tropate sulfate monohydrate (Standard); DL-Hyoscyamine sulfate monohydrate (Standard)
|
Alkaloids
Structural Classification
Other Alkaloids
Atropa belladonna Linn.
Solanaceae
Plants
Source Classification
|
Reference Standards
mAChR
|
|
Atropine (sulfate monohydrate) (Standard) is the analytical standard of Atropine (sulfate monohydrate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .
|
-
-
- HY-114625
-
|
|
Structural Classification
Human Gut Microbiota Metabolites
Ketones, Aldehydes, Acids
Endogenous metabolite
Source Classification
|
Parasite
Mitochondrial Metabolism
|
|
Amquinate is a coccidiostat and a cytochrome b inhibitor. Amquinate blocks cytochrome-mediated electron transport near cytochrome b in mitochondria, acting downstream of coenzyme Q without affecting succinate dehydrogenase or NADH dehydrogenase. Amquinate inhibits succinate- and malate plus pyruvate-supported mitochondrial respiration in Eimeria tenella and does not affect L-ascorbate-supported respiration or any mitochondrial respiration in chicken liver mitochondria. Amquinate exhibits selective anticoccidial activity against wild-type Eimeria tenella. Amquinate can be used for the research of coccidiosis (Eimeria tenella infection) .
|
-
-
- HY-N14010
-
|
|
Natural Products
Microorganisms
Source Classification
|
Bacterial
|
|
Cationomycin inhibits the activity of Gram-positive bacteria and mycobacterium, but has no effect on Gram-negative bacteria, yeast and fungi. The feed containing 50-100 ppm Cationomycin could effectively prevent coccidiosis of chicken .
|
-
-
- HY-12361R
-
|
|
Natural Products
Microorganisms
Source Classification
|
Reference Standards
Parasite
|
|
PF 1022A (Standard) is the analytical standard of PF 1022A. This product is intended for research and analytical applications. PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research[1][2][3].
|
-
-
- HY-N18431
-
-
-
- HY-159201
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B1337S1
-
3 Publications Verification
|
|
Choline-d9 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
|
-
-
- HY-B1337S
-
1 Publications Verification
|
|
Choline-d4 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
|
-
-
- HY-B1337S3
-
|
|
|
Choline-d13 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
|
-
-
- HY-B1337S4
-
1 Publications Verification
|
|
Choline Chloride- 13C3 is the 13C-labeled Choline (chloride). Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
|
-
-
- HY-107814S
-
|
|
|
Nicarbazin-d8 is deuterium labeled Nicarbazin. Nicarbazin is an effective anticoccidial agent for chickens .
|
-
-
- HY-N6726S
-
|
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Fumonisin B3- 13C34 is the 13C labeled Fumonisin B3 (HY-N6726). Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma .
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- HY-101399SA
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γ-Glu-(Phe-13C9,15N) (γ-Glutamylphenylalanine-13C9,15N) TFA is the 13C- and 15N-labeled γ-Glu-Phe TFA (HY-101399A). γ-Glu-Phe TFA is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
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- HY-N6726S1
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Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma .
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- HY-B1337S2
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Choline-d6 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
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- HY-B1148AS
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Furaltadone-d5 is the deuterium labeled Furaltadone (HY-B1148A). Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .
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- HY-101399S
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γ-Glu-(Phe- 13C9, 15N) is the 13C and 15N labeled isotope of γ-Glu-Phe(HY-101399).γ-Glu-Phe or the postenzymatic reaction mixture enhanced the umami intensity of commercial soy sauce and model chicken soup.
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- HY-W701476
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Ethyl phenylglyoxylate-d5 (Ethyl benzoylformate-d5; Phenylglyoxylic acid ethyl ester-d5) is the deuterium labeled Ethyl phenylglyoxylate (HY-W016618). Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .
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- HY-W725504
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2-Hydroxy-3-methylbutanoic acid-d7 is the deuterium labeled 2-Hydroxy-3-methylbutanoic acid (HY-W008150). 2-Hydroxy-3-methylbutanoic acid is an α-hydroxy analogue of valine and a valine precursor that reduces urea excretion. 2-Hydroxy-3-methylbutanoic acid can promote the growth of chickens and rats, and is converted into valine in the body, participating in protein synthesis and maintaining nitrogen balance, thereby supporting animal growth and development. 2-Hydroxy-3-methylbutanoic acid has a more significant effect on the valine-deficient dietary model. 2-Hydroxy-3-methylbutanoic acid is mainly used in animal nutrition research to evaluate its potential application as a nitrogen source substitute in feed .
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- HY-W088066
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pH Modifiers
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Trisodium phosphate dodecahydrate is an Antibacterial agent. Trisodium phosphate dodecahydrate reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate is used in poultry processing .
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