6 Results for "

cholesterol side-chain cleavage enzyme

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "cholesterol side-chain cleavage enzyme" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P81223
Synonyms: cholesterol 20 22 desmolase antibody cholesterol desmolase antibody; cholesterol monooxygenase (side chain cleaving) antibody; cholesterol side chain cleavage enzyme antibody; cholesterol side chain cleavage enzyme mitochondrial antibody; cholesterol side-chain cleavage enzyme antibody; CP11A_HUMAN antibody; CYP11A antibody; CYP11A1 antibody; CYPXIA1 antibody; Cytochrome P450 11A1 antibody; Cytochrome P450 11A1 mitochondrial antibody; Cytochrome P450 family 11 subfamily A polypeptide 1 antibody; Cytochrome P450 subfamily XIA antibody; Cytochrome P450(scc) antibody; Cytochrome P450C11A1 antibody; mitochondrial antibody; P450SCC antibody; Steroid 20 22 lyase antibody;

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-B0237
CAS No.: 125-84-8
Synonyms: DL-Aminoglutethimide
Target:  

Cytochrome P450

Aminoglutethimide (DL-Aminoglutethimide) is an orally active anticonvulsant with various endocrine-related side effects. Aminoglutethimide blocks multiple steroid hormone synthesis pathways by inhibiting several cytochrome P-450-dependent hydroxylases, such as aromatase, cholesterol side-chain cleavage enzyme, 11-hydroxylase, and 18-hydroxylase, with IC50 values of 0.3, 3.5, 120, and 20 μM, respectively. Aminoglutethimide reduces cortisol levels. Aminoglutethimide can be used in research on Cushing's syndrome, breast cancer, and other conditions .
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Cat. No.: HY-115425
CAS No.: 23734-88-5
Synonyms: DL-Aminoglutethimide phosphate
Target:  

Cytochrome P450

Aminoglutethimide phosphate (DL-Aminoglutethimide phosphate) is an orally active anticonvulsant with various endocrine-related side effects. Aminoglutethimide phosphate blocks multiple steroid hormone synthesis pathways by inhibiting several cytochrome P-450-dependent hydroxylases, such as aromatase, cholesterol side-chain cleavage enzyme, 11-hydroxylase, and 18-hydroxylase, with IC50 values of 0.3, 3.5, 120, and 20 μM, respectively. Aminoglutethimide phosphate reduces cortisol levels. Aminoglutethimide phosphate can be used in research on Cushing's syndrome, breast cancer, and other conditions .
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Cat. No.: HY-P705925
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CYP11A1; CYPXIA1; Prev. CYP11A; Cytochrome P450 Family 11 Subfamily A Polypeptide 1 Isoform 3; cholesterol side-chain cleavage enzyme, Mitochondrial; Cytochrome P450 Family 11 Subfamily A Polypeptide 1 Isoform 2; P450SCC; Cytochrome P450, Family 11, Subfa
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-N17617
CAS No.: 70238-51-6
S-Petasin is a phosphodiesterase (PDE) inhibitor with IC50 values of 25.5 μM and 17.5 μM for PDE3 and PDE4, respectively. S-Petasin inhibits cholesterol side-chain cleavage enzyme, 11β-hydroxylase, PPAR-γ, and iNOS induction at RNA and protein levels. S-Petasin induces apoptosis, activates caspases, cleaves PARP, modulates mitochondrial membrane permeability, and regulates BCL2/BAX, p53, Bcl-XL, MMP-2, MMP-9, p21, CDK4, and cyclin D1 expression. S-Petasin reduces inflammatory cell accumulation, cytokine and IgE levels, and enhances serum IgG2a levels. S-Petasin relaxes isolated sensitized guinea pig trachealis and exhibits gastrointestinal anti-spasmodic activity. S-Petasin reduces tonsillitis severity and asthmatic attack frequency. S-Petasin can be used for the research of prostate cancer, obesity, melanoma, allergic asthma, asthma, and peritonitis .
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Cat. No.: HY-179686
CAS No.: 3057862-18-4
Target:  

Cytochrome P450

Research Areas:  

Cancer

CYP11A1-IN-2 (Compound 61) is a selective cholesterol side-chain cleavage enzyme (CYP11A1) inhibitor. CYP11A1-IN-2 can inhibitor steroid biosynthesis and can be used for the research of steroid hormone-dependent cancers, such as prostate cancer .
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