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  5. Petasites hybridus (L.) G.Gaertn., B.Mey. & Schreb.

Petasites hybridus (L.) G.Gaertn., B.Mey. & Schreb.

Petasites hybridus (L.) G.Gaertn., B.Mey. & Schreb. (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N17617
    S-Petasin 70238-51-6
    S-Petasin is a phosphodiesterase (PDE) inhibitor with IC50 values of 25.5 μM and 17.5 μM for PDE3 and PDE4, respectively. S-Petasin inhibits cholesterol side-chain cleavage enzyme, 11β-hydroxylase, PPAR-γ, and iNOS induction at RNA and protein levels. S-Petasin induces apoptosis, activates caspases, cleaves PARP, modulates mitochondrial membrane permeability, and regulates BCL2/BAX, p53, Bcl-XL, MMP-2, MMP-9, p21, CDK4, and cyclin D1 expression. S-Petasin reduces inflammatory cell accumulation, cytokine and IgE levels, and enhances serum IgG2a levels. S-Petasin relaxes isolated sensitized guinea pig trachealis and exhibits gastrointestinal anti-spasmodic activity. S-Petasin reduces tonsillitis severity and asthmatic attack frequency. S-Petasin can be used for the research of prostate cancer, obesity, melanoma, allergic asthma, asthma, and peritonitis.
    S-Petasin
  • HY-N15634
    Anticopalic acid 24470-48-2
    Anticopalic acid is a labdane-type diterpenoid insect antifeedant that exhibits dose-dependent antifeedant activity against the fall armyworm (Spodoptera frugiperda). Anticopalic acid can be isolated from Vitex hemsleyi. Anticopalic acid may be involved in neuroreceptor-mediated insect taste regulation and could be used to develop environmentally friendly antifeedants targeting lepidopteran pests.
    Anticopalic acid
  • HY-N3459
    Isosalicifolin 156974-99-1
    Isosalicifolin is a Lignans product that can be isolated from the herbs of Bupleurum candollei.
    Isosalicifolin