3 Results for "

correctly folded peptide

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "correctly folded peptide" in MCE Product Catalog:

1
Proinsulin C-peptide (human)
Proinsulin C-peptide (human)
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1 Cited Publications
Referencia número: HY-P1856
No. CAS: 33017-11-7
Target:  

Insulin Receptor PDGFR MAPKAPK2 (MK2)

Áreas de investigación:  

Cardiovascular Disease Metabolic Disease Inflammation/Immunology

Proinsulin C-peptide (human) is a peptide consisting of 31 amino acids that links the A and B chains of proinsulin to ensure its correct folding. Proinsulin C-peptide (human) inhibits the high glucose-induced increase in PDGF-β receptor protein expression and the phosphorylation of p42/p44 MAP kinase. Proinsulin C-peptide (human) increases the deformability of erythrocytes derived from type 1 diabetes, inhibits insulin-induced neointimal thickening, and suppresses the proliferation of rat aortic smooth muscle cells cultured under high-glucose conditions .
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Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH
Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH
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Referencia número: HY-P2399
No. CAS: 957780-56-2
Target:  

Drug Intermediate Amino Acid Derivatives

Áreas de investigación:  

Others

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide building block containing a pseudoproline, which is used in studies related to Fmoc solid-phase peptide synthesis. Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH inhibits premature β-sheet aggregation during solid-phase peptide synthesis .
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DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS
DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS
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Referencia número: HY-P5415
No. CAS: 127134-13-8
Target:  

HIV

Áreas de investigación:  

Others

DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a biological active peptide. (DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is also called HIV protease substrate I in some literature. It is widely used for the continuous assay for HIV protease activity. The 11-Kd protease (PR) encoded by the human immunodeficiency virus 1 (HIV-1) is essential for the correct processing of viral polyproteins and the maturation of infectious virus, and is therefore a target for the design of selective acquired immunodeficiency syndrome (AIDS) therapeutics. The FRET-based fluorogenic substrate is derived from a natural processing site for HIV-1 PR. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that is linearly related to the extent of substrate hydrolysis. The fluorescence quantum yields of the HIV-1 PR substrate in the FRET assay increased by 40.0- and 34.4-fold, respectively, per mole of substrate cleaved. Because of its simplicity and precision in the determination of reaction rates required for kinetic analysis, this substrate offers many advantages over the commonly used HPLC or electrophoresis-based assays for peptide substrate hydrolysis by retroviral PRs. Abs/Em = 340nm/490nm.)
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