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dammarane triterpene

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By Targets:	Akt (1) Apoptosis (1) Drug Derivative (2) Insulin Receptor (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) Sirtuin (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Inflammation/Immunology (1) Metabolic Disease (3)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0597

Panaxatriol 3 Publications Verification	Akt Insulin Receptor Apoptosis Reactive Oxygen Species (ROS)	Cardiovascular Disease Metabolic Disease Cancer
Panaxatriol is an orally active dammarane-type tetracyclic triterpene sapogenin. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer ^[1][2][3].

HY-N16751

Notoginsenoside D	Others	Metabolic Disease
Notoginsenoside D is a dammarane-type triterpene oligoglycoside. Notoginsenoside D can be isolated from the dried roots of Panax notoginseng (BURK.) F. H. CHEN. Notoginsenoside D can be used in the research of liver injury .

HY-N2047

Jujuboside B1	Others	Others
Jujuboside B1, a dammarane-type triterpene oligoglycoside, is isolated from Ziziphi Spinosae Semen .

HY-N6252

Gypenoside XLVI 1 Publications Verification	Others	Cancer
Gypenoside XLVI is one of the major dammarane-type triterpenoid saponins from Gynostamma pentaphallum . Gypenoside XLVI has a tetracyclic triterpene structure and possess potent non-small cell lung carcinoma A549 cell inhibitory activity .

HY-N19634

Betulatriterpene C	Others	Others
Betulatriterpene C is a dammarane triterpene found in the glandular trichome exudates of Ibicella lutea .

HY-N0597R

Panaxatriol (Standard)	Reference Standards Others	Others
Panaxatriol (Standard) is the analytical standard of Panaxatriol. This product is intended for research and analytical applications. Panaxatriol is an orally active dammarane-type tetracyclic triterpene sapogenin. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer .

HY-N17995

GypenosideZ-3	Others	Cancer
GypenosideZ-3 is a dammarane triterpene glycoside found in the roots of Machilus yaoshansis .

HY-N18198

Notoginsenoside A	Others	Others
Notoginsenoside A (Compound 6) is a dammarane-type triterpene oligoglycoside found in the roots of Panax quinquefolium L. .

HY-N17972

Floranotoginsenoside D	Others	Others
Floranotoginsenoside D (Compound 4) is a dammarane-type triterpene saponin found in the flowers of Panax notoginseng .

HY-N17607

Foliasalacin A4	Drug Derivative	Others
Foliasalacin A4 (Compound 4) is a dammarane-type triterpene isolated from the leaves of Salacia chinensis .

HY-N17994

GypenosideZ-2	Drug Derivative	Others
GypenosideZ-2 is a dammarane-type triterpene saponin found in the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino .

HY-N18048

Gypenoside CII	Sirtuin	Others
Gypenoside CII is a dammarane-type triterpene saponin that can be isolated from Gynostemma pentaphyllum. Gypenoside CII exerts no significant activating effect on recombinant human Sirt1, while its congeners are potent Sirt1 agonists .

HY-N17992

Gypenoside UL5	Others	Metabolic Disease Inflammation/Immunology
Gypenoside UL5 (Compound UL5) is a dammarane-type triterpene saponin found in Gynostemma pentaphyllum. Gypenoside UL5 shows liver injury-inhibiting, anti-inflammatory and antioxidant properties. Gypenoside UL5 can be used for the research of hepatitis, fatty liver, and liver fibrosis .

Panaxatriol 3 Publications Verification	Panax ginseng C. A. Meyer Triterpenes Structural Classification Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Araliaceae Source Classification	Akt Insulin Receptor Apoptosis Reactive Oxygen Species (ROS)
Panaxatriol is an orally active dammarane-type tetracyclic triterpene sapogenin. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer ^[1][2][3].

Notoginsenoside D	Triterpenes Structural Classification Tetracyclic Triterpenoids Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Araliaceae Source Classification	Others
Notoginsenoside D is a dammarane-type triterpene oligoglycoside. Notoginsenoside D can be isolated from the dried roots of Panax notoginseng (BURK.) F. H. CHEN. Notoginsenoside D can be used in the research of liver injury .

Jujuboside B1	Triterpenes other families Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Others
Jujuboside B1, a dammarane-type triterpene oligoglycoside, is isolated from Ziziphi Spinosae Semen .

Gypenoside XLVI 1 Publications Verification	Triterpenes Classification of Application Fields Terpenoids Cucurbitaceae Plants Disease Research Fields Gynostemma pentaphyllum (Thunb.) Makino Cancer Source Classification	Others
Gypenoside XLVI is one of the major dammarane-type triterpenoid saponins from Gynostamma pentaphallum . Gypenoside XLVI has a tetracyclic triterpene structure and possess potent non-small cell lung carcinoma A549 cell inhibitory activity .

Betulatriterpene C	Ibicella lutea (Lindl.) Van Eselt. Structural Classification Tetracyclic Triterpenoids Martyniaceae Terpenoids Plants Source Classification	Others
Betulatriterpene C is a dammarane triterpene found in the glandular trichome exudates of Ibicella lutea .

Panaxatriol (Standard)	Panax ginseng C. A. Meyer Triterpenes Structural Classification Terpenoids Plants Araliaceae Source Classification	Reference Standards Others
Panaxatriol (Standard) is the analytical standard of Panaxatriol. This product is intended for research and analytical applications. Panaxatriol is an orally active dammarane-type tetracyclic triterpene sapogenin. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer .

GypenosideZ-3	Triterpenes Structural Classification Terpenoids Cucurbitaceae Plants Gynostemma pentaphyllum (Thunb.) Makino Source Classification	Others
GypenosideZ-3 is a dammarane triterpene glycoside found in the roots of Machilus yaoshansis .

Notoginsenoside A	Structural Classification Tetracyclic Triterpenoids Panax quinquefolium Terpenoids Plants Araliaceae Source Classification	Others
Notoginsenoside A (Compound 6) is a dammarane-type triterpene oligoglycoside found in the roots of Panax quinquefolium L. .

Floranotoginsenoside D	Structural Classification Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Plants Araliaceae Steroids Source Classification	Others
Floranotoginsenoside D (Compound 4) is a dammarane-type triterpene saponin found in the flowers of Panax notoginseng .

Foliasalacin A4	Structural Classification Salacia chinensis L. Celastraceae Plants Steroids Source Classification	Drug Derivative
Foliasalacin A4 (Compound 4) is a dammarane-type triterpene isolated from the leaves of Salacia chinensis .

GypenosideZ-2	Triterpenes Structural Classification Terpenoids Cucurbitaceae Plants Gynostemma pentaphyllum (Thunb.) Makino Source Classification	Drug Derivative
GypenosideZ-2 is a dammarane-type triterpene saponin found in the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino .

Gypenoside CII	Structural Classification Cucurbitaceae Plants Gynostemma pentaphyllum (Thunb.) Makino Steroids Source Classification	Sirtuin
Gypenoside CII is a dammarane-type triterpene saponin that can be isolated from Gynostemma pentaphyllum. Gypenoside CII exerts no significant activating effect on recombinant human Sirt1, while its congeners are potent Sirt1 agonists .

Gypenoside UL5	Triterpenes Structural Classification Terpenoids Cucurbitaceae Plants Gynostemma pentaphyllum (Thunb.) Makino Source Classification	Others
Gypenoside UL5 (Compound UL5) is a dammarane-type triterpene saponin found in Gynostemma pentaphyllum. Gypenoside UL5 shows liver injury-inhibiting, anti-inflammatory and antioxidant properties. Gypenoside UL5 can be used for the research of hepatitis, fatty liver, and liver fibrosis .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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dammarane triterpene

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