15 Results for "

endogenous depressions

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "endogenous depressions" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-B1232
CAS No.: 54-36-4
Synonyms: Su-4885
Metyrapone (Su-4885) is a potent and orally active 11β-hydroxylase inhibitor and an autophagy activator, also inhibits the production of aldosterone. Metyrapone inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion. In addition, Metyrapone increases the efficiency of autophagic process via downregulation of mTOR pathway, and interacts with Pseudomonas putida cytochrome P-450. Metyrapone can be used for researching Cushing's syndrome and depression .
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1 Cited Publications
Cat. No.: HY-128733
CAS No.: 122-79-2
Purity:  99.68%
Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, which can be found in urine. Phenyl acetate regulates the metabolism of glutamine. In addition, Phenyl acetate can be used as a detection index for certain diseases, such as depression .
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Cat. No.: HY-142122
CAS No.: 6829-98-7
Purity:  99.90%
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

Imipramine N-oxide is the metabolite of Imipramine. Imipramine N-oxide exhibits low toxicity in rat and mouse experiments. Imipramine N-oxide can be used for the research of endogenous depressions .
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Cat. No.: HY-133159
CAS No.: 865532-70-3
Purity:  ≥95.0%
Synonyms: (-)-Resolvin E2
Resolvin E2 ((-)-Resolvin E2) is an endogenous lipid mediator produced from eicosapentaenoic acid (EPA) under the catalysis of 5-lipoxygenase (5-LOX), and its production increases in hypoxic environments. Resolvin E2 antagonizes BLT1, partially activates ChemR23, and promotes ubiquitin-proteasome-mediated degradation of COX-2. Resolvin E2 reduces the production of prostaglandin E2, blocks polymorphonuclear leukocyte infiltration, and promotes the resolution of airway inflammation. Resolvin E2 ameliorates lipopolysaccharide (LPS) (HY-D1056)-induced depressive-like behaviors . Resolvin E2 can be used in research related to depression, murine peritonitis, neonatal asthma, and other conditions .
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Cat. No.: HY-N10423
CAS No.: 18423-69-3
Synonyms: (-)-Cubebin
Cubebin ((-)-Cubebin), a dibenzyl butyrolactone lignan, is an orally active AChE inhibitor. Cubebin binds to active sites of NF-κB, TNF-α, and TGF-β1 via hydrogen and hydrophobic interactions, obstructing critical residues to inhibit pro-inflammatory or renal fibrosis-related activity. Cubebin enhances p38 MAPK phosphorylation to increase tyrosinase gene expression, stimulating melanogenesis via elevated tyrosinase activity, expression, and mRNA levels. Cubebin reduces oxidative stress via enhanced endogenous antioxidant enzyme activity and inhibited lipid peroxidation, regulates lipid metabolism, improves glycemic control, and exerts renoprotective effects via reduced renal dysfunction markers and improved renal architecture. Cubebin shows antimicrobial activity. Cubebin exerts larvicidal activity against Angiostrongylus cantonensis larvae, with no cytotoxicity toward monkey or human cell lines or Caenorhabditis elegans. Cubebin can be used for the research of diabetic nephropathy, melanoma, colon adenocarcinoma, neuroangiostrongyliasis, Alzheimer’s disease (AD) and depression .
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Cat. No.: HY-128733R
CAS No.: 122-79-2
Phenyl acetate (Standard) is the analytical standard of Phenyl acetate. This product is intended for research and analytical applications. Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, which can be found in urine. Phenyl acetate regulates the metabolism of glutamine. In addition, Phenyl acetate can be used as a detection index for certain diseases, such as depression.
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Cat. No.: HY-W015882R
CAS No.: 646-07-1
Synonyms: Isocaproic acid (Standard)
4-Methylpentanoic acid (Isocaproic acid) (Standard) is an analytical standard form of 4-Methylpentanoic acid (HY-W015882). This product is intended for research and analytical applications. 4-Methylpentanoic acid (Isocaproic Acid) is a short-chain fatty acid, an endogenous metabolite, and a metabolite of 20 α-hydroxycholesterol (HY-12316), which can be found in feces. The concentration of 4-Methylpentanoic acid is closely related to some diseases, such as depression. 4-Methylpentanoic acid can also be used in the research of cholesterol metabolism .
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Cat. No.: HY-119426
CAS No.: 14769-74-5
Synonyms: (+)-Tetramisole; Dextramisole
Research Areas:  

Neurological Disease

Dexamisole ((+)-Tetramisole) is an orally active dextral tetramisole with mood-enhancing and mental tension-improving effects. Dexamisole can be used in studies related to neurotic depression or endogenous retarded depression .
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Cat. No.: HY-128733S
CAS No.: 22705-26-6
Phenyl acetate-d5 is the deuterium labeled Phenyl acetate. Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, which can be found in urine. Phenyl acetate regulates the metabolism of glutamine. In addition, Phenyl acetate can be used as a detection index for certain diseases, such as depression .
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Cat. No.: HY-125047
CAS No.: 23226-37-1
Synonyms: UK 3557 tosylate
Daledalin tosylate is an orally active indoline antidepressant targeting noradrenaline and serotonin transporters in the brain. Daledalin tosylate enhances central monoaminergic neurotransmission to alleviate depressive symptoms. Daledalin tosylate is proming for rasearch of depression, including endogenous and neurotic depression .
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Cat. No.: HY-125047A
CAS No.: 22136-27-2
Synonyms: UK 3557
Daledalin (UK 3557) is an orally active indoline antidepressant targeting noradrenaline and serotonin transporters in the brain. Daledalin enhances central monoaminergic neurotransmission to alleviate depressive symptoms. Daledalin is proming for rasearch of depression, including endogenous and neurotic depression .
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Cat. No.: HY-P1625
CAS No.: 103614-28-4
Synonyms: Dynorphin A ethylamide (1-9)
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Daeatal (Dynorphin A ethylamide (1-9)) is an ethylamine-modified dynorphin fragment that can be used in the study of analgesia, addiction, depression, etc. Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease .
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Cat. No.: HY-B1232A
CAS No.: 908-35-0
Synonyms: Su-4885 Tartrate
Metyrapone (Su-4885) Tartrate is a potent and orally active 11β-hydroxylase inhibitor and an autophagy activator, also inhibits the production of aldosterone. Metyrapone Tartrate inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion. In addition, Metyrapone Tartrate increases the efficiency of autophagic process via downregulation of mTOR pathway, and interacts with Pseudomonas putida cytochrome P-450. Metyrapone Tartrate can be used for researching Cushing's syndrome and depression .
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Cat. No.: HY-B1232R
CAS No.: 54-36-4
Synonyms: Su-4885 (Standard)
Metyrapone (Standard) is the analytical standard of Metyrapone. This product is intended for research and analytical applications. Metyrapone (Su-4885) is a potent and orally active 11β-hydroxylase inhibitor and an autophagy activator, also inhibits the production of aldosterone. Metyrapone inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion. In addition, Metyrapone increases the efficiency of autophagic process via downregulation of mTOR pathway, and interacts with Pseudomonas putida cytochrome P-450. Metyrapone can be used for researching Cushing's syndrome and depression .
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Cat. No.: HY-119426A
CAS No.: 16595-76-9
Synonyms: (+)-Tetramisole hydrochloride; Dextramisole hydrochloride
Research Areas:  

Neurological Disease

Dexamisole hydrochloride ((+)-Tetramisole (hydrochloride)) is an orally active dextral tetramisole with mood-enhancing and mental tension-improving effects. Dexamisole hydrochloride can be used in studies related to neurotic depression or endogenous retarded depression .
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