14769-74-5
14769-74-5
Chemical Structure
Dexamisole
Synonym(s): (+)-Tetramisole; Dextramisole
- CAS No.: 14769-74-5
- Formula:C11H12N2S
- Molecular Weight:204.29
IUPAC Name: (R)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
InChIKey: HLFSDGLLUJUHTE-JTQLQIEISA-N
SMILES: C12=N[C@@H](CN1CCS2)C3=CC=CC=C3
Biological Activity: Dexamisole ((+)-Tetramisole) is an orally active dextral tetramisole with mood-enhancing and mental tension-improving effects. Dexamisole can be used in studies related to neurotic depression or endogenous retarded depression[1][2][3].
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Dexamisole | Dexamisole ((+)-Tetramisole) is an orally active dextral tetramisole with mood-enhancing and mental tension-improving effects. Dexamisole can be used in studies related to neurotic depression or endogenous retarded depression. | |||||||||||||||||||||
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References
- [1]. Bobon J, et al. A Pilot Open Trial of Dexamisole (R 12. 563) in Retarded Depression: Preliminary Results. Journal of International Medical Research. 1974 Mar‑Apr;2(2):111‑?.
- [2]. Bertucci C, et al. Determination of levamisole and tetramisole in seized cocaine samples by enantioselective high-performance liquid chromatography and circular dichroism detection. Journal of chromatography. A. 2014 Oct 10;1363:150-4. [Content Brief]
- [3]. Losacker M, et al. Chiral pharmacokinetics of tetramisole stereoisomers-Enantioselective quantification of levamisole and dexamisole in serum samples from users of adulterated cocaine. Drug testing and analysis. 2022 Jun;14(6):1053-1064. [Content Brief]
