1 Result for "

furofuran-type lignin

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "furofuran-type lignin" in MCE Product Catalog:

1
(+)-Medioresinol
(+)-Medioresinol
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Cat. No.: HY-N3307
CAS No.: 40957-99-1
Category:  

Cardiovascular Disease Neurological Disease Oleaceae Fraxinus mandshurica Rupr. Phenols Polyphenols Plants Disease Research Fields

Target:  

Bacterial Fungal Reactive Oxygen Species (ROS) Apoptosis MMP Interleukin Related PI3K Akt mTOR PPAR PGC-1α Pyroptosis

(+)-Medioresinol is a furofuran-type lignan with antifungal and antibacterial properties. (+)-Medioresinol synergizes with antibiotics to exert antimicrobial and antibiofilm effects. (+)-Medioresinol induces intracellular ROS accumulation and mitochondrial-mediated apoptosis in Candida albicans. (+)-Medioresinol inhibits LPS (HY-D1056)-stimulated IL-12p40 production. (+)-Medioresinol is a PGC-1α activator that protects against endothelial cell pyroptosis in ischemic stroke via the PPARα-GOT1 axis. (+)-Medioresinol can be used in research on fungal and bacterial infection, inflammation, and ischemic stroke .
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