39 Results for "

galactosamine

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "galactosamine" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-N1441
CAS No.: 482-39-3
Synonyms: Kaempferol-3-O-rhamnoside
Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin .
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3
3 Cited Publications
Cat. No.: HY-42682
CAS No.: 1772-03-8
Synonyms: D-galactosamine HCl
D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure .
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1
1 Cited Publications
Cat. No.: HY-114365
CAS No.: 108320-87-2
Purity:  99.95%
Synonyms: UDP-N-acetyl-D-galactosamine disodium
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate for EpsC115. EpsC115 is a mutant with N-terminal residues 1-115 deleted from the exopolymeric substance (EPS). UDP-GalNAc disodium is a donor substrate for many N-acetylgalactosaminyltransferases, which transfer GalNAc from nucleotide sugars to sugar or peptide acceptors. UDP-GalNAc disodium provides a sugar group donor for glycosylation reactions. UDP-GalNAc disodium can be used in cancer research, such as colorectal and breast cancer .
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1
1 Cited Publications
Cat. No.: HY-148089
CAS No.: 1637600-16-8
Target:  

Transthyretin (TTR)

Research Areas:  

Neurological Disease

Eplontersen is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases .
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1
1 Cited Publications
Cat. No.: HY-148089A
CAS No.: 2131025-75-5
Purity:  96.92%
Target:  

Transthyretin (TTR)

Research Areas:  

Neurological Disease

Eplontersen sodium the sodium salt form of Eplontersen (HY-148089). Eplontersen sodium is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases .
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Cat. No.: HY-128852
CAS No.: 14215-68-0
Purity:  ≥98.0%
N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets . N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin .
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Cat. No.: HY-153492A
Purity:  98.82%
Synonyms: AMG 890 sodium; ARC-LPA sodium
Research Areas:  

Inflammation/Immunology

Olpasiran (AMG 890, ARC-LPA) sodium is an N-acetyl galactosamine (GalNAc)-conjugated, hepatocyte-targeted siRNA. Olpasiran sodium directly inhibits LPA messenger RNA translation in hepatocytes and potently reduce Lp(a) concentration. Olpasiran sodium can be used for the research of cardiovascular disease, such as atherosclerosis .
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Cat. No.: HY-147062
CAS No.: 18191-20-3
Purity:  98.61%
Research Areas:  

Metabolic Disease

N-acetyl-D-galactosamine 6-phosphate is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). N-Acetyl-D-galactosamine-6-phosphate can be hydrolyze by NagA .
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Cat. No.: HY-153497A
CAS No.: 2172852-12-7
Purity:  98.33%
Synonyms: IONIS ANGPT-L3Rx sodium; ISIS 703802 sodium
Target:  

ANGPTL

Research Areas:  

Metabolic Disease

Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.
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Cat. No.: HY-113407CR
D-Fructose-6-phosphate disodium monohydrate (Standard) is the analytical standard of D-Fructose-6-phosphate disodium monohydrate. D-Fructose-6-phosphate is an intermediate of Glycolysis. D-Fructose-6-phosphate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
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Cat. No.: HY-NP083A
Synonyms: WFA (Biotin)
Wisteria Floribunda Lectin (Biotin) (WFA (Biotin)) is a biotinylated lectin with affinity for N-acetyl-D-galactosamine .
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Cat. No.: HY-42682R
CAS No.: 1772-03-8
Synonyms: D-galactosamine HCl (Standard)
D(+)-Galactosamine (hydrochloride) (Standard) is the analytical standard of D(+)-Galactosamine (hydrochloride). This product is intended for research and analytical applications. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure .
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Cat. No.: HY-N1441R
CAS No.: 482-39-3
Synonyms: Kaempferol-3-O-rhamnoside (Standard)
Afzelin (Standard) is the analytical standard of Afzelin. This product is intended for research and analytical applications. Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin .
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Cat. No.: HY-W145694
CAS No.: 660839-03-2
N-Acetyl-D-galactosamine-4-O-sulfate sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-153497
CAS No.: 2097587-62-5
Synonyms: IONIS ANGPT-L3Rx; ISIS 703802
Target:  

ANGPTL

Research Areas:  

Metabolic Disease

Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins.
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Cat. No.: HY-42682S1
CAS No.: 478518-54-6
Synonyms: D-galactosamine-13C hydrochloride
D(+)-Galactosamine- 13C (hydrochloride) is the 13C labeled D(+)-Galactosamine hydrochloride. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and
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Cat. No.: HY-W005729
CAS No.: 3006-60-8
Research Areas:  

Others

β-D-Galactosamine pentaacetate is an intermediate in the synthesis of triantennary N-Acetylgalactosamine ligands. β-D-Galactosamine pentaacetate can be studied in liver-targeted delivery of siRNA research .
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Cat. No.: HY-W551412
CAS No.: 3554-90-3
β-D-Galactosyl-(1→3)-N-acetyl-D-galactosamine is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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Cat. No.: HY-N10380
CAS No.: 1534433-74-3
Inonotusol F is a triterpene isolated from Inonotus obliquus. Inonotusol F shows hepatoprotective effects against D-galactosamine-induced WB-F344 cell damage .
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Cat. No.: HY-N4243
CAS No.: 108944-67-8
Neocurdione is a hepatoprotective sesquiterpene isolated from Curcuma zedoaria rhizome. Neocurdione exerts potent effect on D-galactosamine- (D-Gain) and lipopolysaccharide- (LPS) induced acute liver injury in mice .
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