12 Results for "

glutathione biosynthesis

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "glutathione biosynthesis" in MCE Product Catalog:

22
22 Publications Verification
Cat. No.: HY-113324
CAS No.: 53-57-6
Purity:  99.49%
NADPH is a coenzyme of glutathione reductase (GR), thioredoxin reductase (TrxR) and NADPH oxidase (NOX), and participates in redox reactions as a hydrogen donor. NADPH has the characteristic of selectively participating in the regulation of cellular redox homeostasis. NADPH exerts antioxidant activity and resists reactive oxygen species (ROS) damage by providing reducing equivalents for the regeneration of glutathione (GSH) and thioredoxin (Trx); at the same time, it acts as a substrate of NOX to generate superoxide anions, mediating oxidative stress and immune response. NADPH participates in maintaining the intracellular reducing environment, biosynthesis and regulating gene expression (such as the Nrf2 pathway), and is mainly used in the study of oxidative stress-related diseases (such as cardiovascular diseases, neurodegenerative diseases, cancer) and immune regulation mechanisms .
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2
2 Cited Publications
Cat. No.: HY-W451275
CAS No.: 928712-10-1
Target:  

Apoptosis

Research Areas:  

Cancer

HG106 is an effective SLC7A11 inhibitor. HG106 mediates apoptosis by increasing oxidative stress and endoplasmic reticulum stress, and it has antitumor activity .
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2
2 Cited Publications
Cat. No.: HY-A0087
CAS No.: 6197-30-4
Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .
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Cat. No.: HY-136376
CAS No.: 135590-91-9
Purity:  99.45%
Research Areas:  

Others

Mefenpyr-diethyl is a pyrazoline-type herbicide safener that functions to enhance lipid biosynthesis. Mefenpyr-diethyl effectively prevents herbicide-induced phytotoxic damage caused by herbicides such as fenoxaprop-p-ethyl (HY-B2013) and mesosulfuron-methyl (HY-126987) by protecting cereal crops including wheat. Mefenpyr-diethyl significantly increases lipid content in wheat either when applied alone or in combination with the herbicide fenoxaprop-p-ethyl. The mechanism of action of Mefenpyr-diethyl does not involve the induction of glutathione S-transferase (GST) activity in wheat .
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Cat. No.: HY-N7436
CAS No.: 2179-60-4
Methyl propyl disulfide is an orally administrable volatile sulfide present in onions. Methyl propyl disulfide reduces the activity of spermine N'1-acetyltransferase (SAT), inhibits cell proliferation, and decreases the induction of placental glutathione S-transferase (GST-P)-positive hepatocyte foci in rat livers. Methyl propyl disulfide can be used in studies related to the mechanism of hepatocarcinogenesis .
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Cat. No.: HY-120253
CAS No.: 203313-25-1
Purity:  94.20%
Synonyms: BY-108330
Spirotetramat (BY-108330) is an orally active Insecticide and lipid biosynthesis inhibitor. Spirotetramat regulates the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), with short-term exposure increasing their activities and long-term exposure altering their activities. Spirotetramat induces the activity and mRNA expression of carboxylesterase (CarE). Spirotetramat induces oxidative stress and lipid peroxidation in tadpoles. Spirotetramat is toxic to amphibian tadpoles and exhibits sublethal/non-lethal toxicity to amphibians. Spirotetramat causes death in immature psyllids, aphids, scale insects, mealybugs, whiteflies and thrips, and shows a high lethal rate against Cacopsylla pyri nymphs. Spirotetramat reduces the fecundity of Aphis gossypii. Spirotetramat induces tolerance in the offspring of exposed Aphis gossypii, and acts on Myzus persicae, Bemisia tabaci and Tetranychus urticae .
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Cat. No.: HY-118642
CAS No.: 232617-15-1
D-Ribose-L-cysteine ​​is an orally active cysteine ​​analog. D-Ribose-L-cysteine ​​improves cellular antioxidant capacity by enhancing intracellular glutathione (GSH) biosynthesis. In addition, D-Ribose-L-cysteine ​​has a memory-enhancing effect and can reverse Scopolamine (HY-N0296)-induced memory impairment by inhibiting oxidative stress and acetylcholinesterase (AChE) activity. D-Ribose-L-cysteine ​​can be used in the study of neurodegenerative and cardiovascular diseases .
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Cat. No.: HY-106064A
CAS No.: 88851-62-1
Synonyms: U 60257B
Piriprost potassium (U 60257B) is an inhibitor of Glutathione-S-transferase and leukotriene biosynthesis inhibitor. Piriprost potassium inhibits the biosynthesis of leukotriene C/D without affecting cyclooxygenase-mediated arachidonic acid metabolites. Piriprost potassium increases the activity of alkaline phosphatase (ALP). Piriprost potassium antagonizes contractions induced by leukotriene C/D in vitro. Piriprost potassium is used in asthma research .
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Cat. No.: HY-128503
CAS No.: 114627-30-4
Target:  

HIV

Research Areas:  

Infection Cardiovascular Disease

TEI-2306 is a precursor of glutathione biosynthesis. TEI-2306 possesses a unique anti-HIV-1 activity in both chronically and acutely infected cells, and even for free viruses. TEI-2306 can be used for the study of myocardial ischaemia .
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Cat. No.: HY-W654296
Octocrylene- 13C3 is the 13C-labeled Octocrylene (HY-A0087). Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .
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Cat. No.: HY-106064
CAS No.: 79672-88-1
Synonyms: U-60257
Piriprost (U-60257) is an inhibitor of Glutathione-S-transferase and leukotriene biosynthesis inhibitor. Piriprost inhibits the biosynthesis of leukotriene C/D without affecting cyclooxygenase-mediated arachidonic acid metabolites. Piriprost increases the activity of alkaline phosphatase (ALP). Piriprost antagonizes contractions induced by leukotriene C/D in vitro. Piriprost is used in asthma research .
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Cat. No.: HY-W747529
CAS No.: 117337-19-6
Target:  

Herbicide

Research Areas:  

Others

Fluthiacet-methyl is an isoxazole herbicide and also a protoporphyrinogen oxidase (Protox) inhibitor. Fluthiacet-methyl inhibits chlorophyll biosynthesis in cotyledons of velvetleaf and cotton. Fluthiacet-methyl induces electrolyte leakage in cotyledons of sensitive plants such as velvetleaf and cotton. Fluthiacet-methyl induces the accumulation of protoporphyrin IX in cotton cotyledons .
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