Search Result
Results for "
hemisulfate
" in MedChemExpress (MCE) Product Catalog:
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- HY-18234A
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- HY-B1276
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- HY-B1496
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SKF 385 hemisulfate
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Monoamine Oxidase
Histone Demethylase
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Neurological Disease
Cancer
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Tranylcypromine (SKF 385) hemisulfate is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. Tranylcypromine hemisulfate is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Tranylcypromine has antidepressant effects .
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- HY-B0152B
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6-Aminopurine hemisulfate; Vitamin B4 hemisulfate
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DNA/RNA Synthesis
Endogenous Metabolite
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Cancer
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Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
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- HY-B0436
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Albuterol hemisulfate; AH-3365 hemisulfate
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Adrenergic Receptor
ERK
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Inflammation/Immunology
Cancer
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Salbutamol (Albuterol) hemisulfate is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol hemisulfate promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol hemisulfate can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease .
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- HY-17423A
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Abacavir hemisulfate; ABC sulfate
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Reverse Transcriptase
HIV
Telomerase
Apoptosis
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Infection
Cancer
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Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir sulfate can inhibits the replication of HIV. Abacavir sulfate shows anticancer activity in prostate cancer cell lines. Abacavir sulfate can trespass the blood-brain-barrier and suppresses telomerase activity .
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- HY-N0716A
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- HY-B0802
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Terbutaline hemisulfate
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Adrenergic Receptor
Antibiotic
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Endocrinology
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Terbutaline sulfate is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol . Terbutaline sulfate can be used in asthma symptom research .
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- HY-137958
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AT-527
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HCV
SARS-CoV
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Infection
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Bemnifosbuvir hemisulfate (AT-527), a hemisulfate salt of AT-511, a guanosine nucleotide proagent, is a potent and orally active HCV viral replication inhibitor. Bemnifosbuvir hemisulfate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC90=0.47 μM). Bemnifosbuvir hemisulfate has pangenotypic antiviral activity .
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- HY-B0883
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Bacterial
Fluorescent Dye
Potassium Channel
DNA/RNA Synthesis
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Infection
Neurological Disease
Cancer
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3,6-Diaminoacridine hemisulfate is a multifunctional acridine compound. 3,6-Diaminoacridine hemisulfate is an acridine dye and also a DNA inserter. 3,6-Diaminoacridine hemisulfate is a potent broad-spectrum antibacterial agent. Its mechanism is to insert into bacterial DNA, interfering with replication and transcription, leading to bacterial lysis. 3,6-Diaminoacridine hemisulfate is a Kir3.2 potassium channel blocker and can be used to study the neurological phenotype of Down syndrome. 3,6-Diaminoacridine hemisulfate can penetrate the stratum corneum of the skin and accumulate in the cell nucleus. Long-term exposure may induce skin cancer or other malignant tumors .
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- HY-N2320
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Eserine hemisulfate
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Cholinesterase (ChE)
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Neurological Disease
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Physostigmine hemisulfate (Eserine hemisulfate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine hemisulfate can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine hemisulfate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine hemisulfate is also an antidote for anticholinergic poisoning .
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- HY-N0930A
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AMPK
Bacterial
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Infection
Metabolic Disease
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Galegine hemisulfate, a guanidine derivative, contributes to weight loss in mice. Galegine hemisulfate activates AMPK in 3T3-L1 adipocytes and L6 myotubes, as well as in the H4IIE rat hepatoma and HEK293 human kidney cell lines. Galegine hemisulfate has antibacterial activity, with minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains .
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- HY-W020772
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Reactive Oxygen Species (ROS)
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Cancer
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Aminoguanidine hemisulfate is an inhibitor of NOS and ROS. Aminoguanidine hemisulfate abolishes ANE-induced ROS production in vitro. Aminoguanidine hemisulfate is used for cancer research .
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- HY-D0143B
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Parasite
Potassium Channel
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Infection
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Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV, with an IC50 of 169 μM .
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- HY-119759A
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Antibiotic
Fungal
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Infection
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Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM .
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- HY-B1538A
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DL-Bamethane hemisulfate
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Endogenous Metabolite
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Cardiovascular Disease
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Bamethan (DL-Bamethane) hemisulfate is a vasodilator that exhibits significant activity in enhancing blood flow and reducing vascular resistance. Bamethan hemisulfate plays a crucial role in the treatment of cardiovascular conditions by improving oxygen delivery to tissues. Bamethan hemisulfate also aids in the management of hypertension through its relaxing effects on blood vessels.
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- HY-B1624A
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Debrisoquine hemisulfate; Isocaramidine hemisulfate; Ro 5-3307/1 hemisulfate
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Endogenous Metabolite
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Infection
Cardiovascular Disease
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Debrisoquin (Isocaramidine) hemisulfate is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquin hemisulfate can be used for antiviral research .
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- HY-B0802R
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Terbutaline hemisulfate (Standard)
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Reference Standards
Adrenergic Receptor
Antibiotic
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Endocrinology
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Terbutaline (sulfate) (Standard) is the analytical standard of Terbutaline (sulfate). This product is intended for research and analytical applications. Terbutaline sulfate is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol . Terbutaline sulfate can be used in asthma symptom research .
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- HY-W012037
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8-Quinolinol hemisulfate
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Environmental Pollutants
Antibiotic
Bacterial
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Infection
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8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
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- HY-108353A
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- HY-B0436R
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Albuterol hemisulfate (Standard); AH-3365 hemisulfate (Standard)
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Reference Standards
Adrenergic Receptor
ERK
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Inflammation/Immunology
Cancer
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Salbutamol (Albuterol) hemisulfate (Standard) is the analytical standard of Salbutamol hemisulfate (HY-B0436). This product is intended for research and analytical applications. Salbutamol (Albuterol) hemisulfate is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol hemisulfate promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol hemisulfate can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease.
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- HY-W012037R
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8-Quinolinol hemisulfate (Standard)
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Reference Standards
Bacterial
Antibiotic
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Infection
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8-Hydroxyquinoline (hemisulfate) (Standard) is the analytical standard of 8-Hydroxyquinoline (hemisulfate). This product is intended for research and analytical applications. 8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
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- HY-B1276R
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Metaproterenol sulfate (Standard)
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Reference Standards
Adrenergic Receptor
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Cardiovascular Disease
Inflammation/Immunology
Endocrinology
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Metaproterenol (hemisulfate) (Standard) is the analytical standard of Metaproterenol (hemisulfate). This product is intended for research and analytical applications. Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity .
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- HY-B0433B
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Flavivirus
Dengue Virus
Parasite
Potassium Channel
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Infection
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Quinine hemisulfate is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine hemisulfate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM .
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- HY-B0152BR
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6-Aminopurine hemisulfate (Standard); Vitamin B4 hemisulfate (Standard)
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DNA/RNA Synthesis
Endogenous Metabolite
Reference Standards
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Cancer
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Adenine (hemisulfate) (Standard) is the analytical standard of Adenine (hemisulfate). This product is intended for research and analytical applications. Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
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- HY-18234AR
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Reference Standards
Cathepsin
Ser/Thr Protease
Virus Protease
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Infection
Inflammation/Immunology
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Leupeptin (hemisulfate) (Standard) is the analytical standard of Leupeptin (hemisulfate). This product is intended for research and analytical applications. Leupeptin hemisulfate is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin hemisulfate potently inhibits serine, cysteine and threonine proteases. Leupeptin hemisulfate inhibits Mpro (the main protease of SARS-CoV-2) and also has anti-inflammatory activity[1][2][3].
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- HY-119759AR
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Antibiotic
Reference Standards
Fungal
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Infection
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Lipoxamycin (hemisulfate) (Standard) is the analytical standard of Lipoxamycin (hemisulfate). This product is intended for research and analytical applications. Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM[1][2].
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- HY-B0919R
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CI-337 (Standard); O-Diazoacetyl-L-serine (Standard); P-165 (Standard)
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Reference Standards
Bacterial
Antibiotic
DNA/RNA Synthesis
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Infection
Cancer
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Bamethan (hemisulfate) (Standard) is the analytical standard of Bamethan (hemisulfate). This product is intended for research and analytical applications. Bamethan (DL-Bamethane) hemisulfate is a vasodilator that exhibits significant activity in enhancing blood flow and reducing vascular resistance. Bamethan hemisulfate plays a crucial role in the treatment of cardiovascular conditions by improving oxygen delivery to tissues. Bamethan hemisulfate also aids in the management of hypertension through its relaxing effects on blood vessels.
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- HY-W995025A
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(+)-Actinobolin hemisulfate
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Antibiotic
Bacterial
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Infection
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Actinobolin hemisulfate ((+)-Actinobolin hemisulfate) is the hemisulfate form of Actinobolin (HY-W995025). Actinobolin hemisulfate is an antibiotic, that inhibits protein synthesis by targeting bacterial and eukaryotic ribosomes. Actinobolin hemisulfate inhibits Mycobacterium smegmatis, Escherichia coli and rabbit reticulocyte lysate (RRL) with an IC50 of 19.2, 27.9, and 288 μmol/L, respectively .
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- HY-B1538AR
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DL-Bamethane hemisulfate (Standard)
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Endogenous Metabolite
Reference Standards
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Cardiovascular Disease
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Bamethan (hemisulfate) (Standard) is the analytical standard of Bamethan (hemisulfate). This product is intended for research and analytical applications. Bamethan (DL-Bamethane) hemisulfate is a vasodilator that exhibits significant activity in enhancing blood flow and reducing vascular resistance. Bamethan hemisulfate plays a crucial role in the treatment of cardiovascular conditions by improving oxygen delivery to tissues. Bamethan hemisulfate also aids in the management of hypertension through its relaxing effects on blood vessels.
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- HY-N0716AR
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- HY-108973
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CGP 15210G hemisulfate
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5-HT Receptor
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Neurological Disease
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Ifoxetine (CGP 15210G) hemisulfate is an inhibitor of 5-HT reuptake. Ifoxetine hemisulfate specifically and selectively blocks the 5-HT reuptake in the brain without affecting the 5-HT uptake processes in the periphery (blood platelets). Ifoxetine hemisulfate inhibits the uptake of radiolabelled 5-HT into rat brain synaptosomes in vitro or ex vivo. Ifoxetine hemisulfate has antidepressant properties .
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- HY-W558568
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- HY-160080
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Others
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Others
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Creatinol (hemisulfate) is the N-ethyl analogue of creatine. Creatinol (hemisulfate) can be used for various researches .
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- HY-12689B
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AG-348 hemisulfate
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Pyruvate Kinase
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Metabolic Disease
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Mitapivat hemisulfate is an orally active pyruvate kinase allosteric activator. Mitapivat hemisulfate increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat hemisulfate can be used in study of PK deficiency .
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- HY-B1276S
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- HY-138454
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Mercaptoethylguanidine hemisulfate
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NO Synthase
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Inflammation/Immunology
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MEG (Mercaptoethylguanidine) hemisulfate is a potent and selective inhibitor of the inducible NO synthase (iNOS), with EC50s of 11.5, 110, and 60 μM for iNOS, ecNOS, and bNOS respectively in tissue homogenates. MEG hemisulfate is also a potent scavenger of peroxynitrite and inhibits peroxynitrite-induced oxidative processes. MEG hemisulfate has a protective effect in many experimental models of inflammation, including ischemia/reperfusion injury, periodontitis, hemorrhagic shock, inflammatory bowel disease, and endotoxic and septic shock .
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- HY-B1496R
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SKF 385 hemisulfate (Standard)
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Reference Standards
Monoamine Oxidase
Histone Demethylase
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Neurological Disease
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Tranylcypromine (hemisulfate) (Standard) is the analytical standard of Tranylcypromine (hemisulfate). This product is intended for research and analytical applications. Tranylcypromine (SKF 385) hemisulfate is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. Tranylcypromine hemisulfate is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Tranylcypromine has antidepressant effects .
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- HY-W741999
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- HY-136887
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Bacterial
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Infection
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Arphamenine B hemisulfate is a Zn 2+-dependent exopeptidase that selectively removes arginine and/or lysine residues from the NH2-terminus of several peptide substrates. Arphamenine B hemisulfate is an inhibitor of aminopeptidase B that can be isolated from bacteria. Arphamenine B hemisulfate enhances the immune response and is used to characterize novel proteases .
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- HY-W018475B
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MK 462 hemisulfate hemihydrate
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5-HT Receptor
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Neurological Disease
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Rizatriptan (MK 462) hemisulfate hemihydrate is the agonist for 5-HT1B and 5-HT1D. Rizatriptan hemisulfate hemihydrate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system .
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- HY-12689A
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AG-348 hemisulfate sesquihydrate
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Pyruvate Kinase
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Metabolic Disease
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Mitapivat hemisulfate sesquihydrate (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency .
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- HY-17423AR
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Abacavir hemisulfate (Standard); ABC sulfate (Standard)
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Reference Standards
Reverse Transcriptase
HIV
Telomerase
Apoptosis
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Infection
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Abacavir (sulfate) (Standard) is the analytical standard of Abacavir (sulfate). This product is intended for research and analytical applications. Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir sulfate can inhibits the replication of HIV. Abacavir sulfate shows anticancer activity in prostate cancer cell lines. Abacavir sulfate can trespass the blood-brain-barrier and suppresses telomerase activity .
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- HY-G0023R
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Niraparib carboxylic acid metabolite M1 (Standard); M1 metabolite of niraparib (Standard)
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Reference Standards
Drug Metabolite
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Others
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Berberine (hemisulfate) (Standard) is the analytical standard of Berberine (hemisulfate). This product is intended for research and analytical applications. Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity .
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- HY-145482R
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Drug Metabolite
Reference Standards
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Neurological Disease
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8-Hydroxyquinoline (hemisulfate) (Standard) is the analytical standard of 8-Hydroxyquinoline (hemisulfate). This product is intended for research and analytical applications. 8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
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- HY-B0938
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- HY-15498B
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BMS-927711 hemisulfate; BHV-3000 hemisulfate
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CGRP Receptor
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Neurological Disease
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Rimegepant (BMS-927711) hemisulfate is a potent, orally active, selective and competitive calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki of 0.027 nM and an IC50 of 0.14 nM for hCGRP receptor. Rimegepant hemisulfate can be used for migraine research .
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- HY-W014021R
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Reference Standards
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4-(Methylamino)phenol hemisulfate (Standard) is the analytical standard of 4-(Methylamino)phenol hemisulfate. This product is intended for research and analytical applications.
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- HY-W653901
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Drug Intermediate
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Others
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2-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-Isoquinolinetriol hemisulfate hydrate is a Terbutaline (HY-B0802A) impurity.
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- HY-W008687R
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Reference Standards
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3-Amino-1H-pyrazole-4-carboxamide sulfate(2:1) (Standard) is the analytical standard of 3-Amino-1H-pyrazole-4-carboxamide sulfate(2:1). This product is intended for research and analytical applications.
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- HY-B0883
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蛍光色素
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3,6-Diaminoacridine hemisulfate is a multifunctional acridine compound. 3,6-Diaminoacridine hemisulfate is an acridine dye and also a DNA inserter. 3,6-Diaminoacridine hemisulfate is a potent broad-spectrum antibacterial agent. Its mechanism is to insert into bacterial DNA, interfering with replication and transcription, leading to bacterial lysis. 3,6-Diaminoacridine hemisulfate is a Kir3.2 potassium channel blocker and can be used to study the neurological phenotype of Down syndrome. 3,6-Diaminoacridine hemisulfate can penetrate the stratum corneum of the skin and accumulate in the cell nucleus. Long-term exposure may induce skin cancer or other malignant tumors .
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| 製品番号 |
製品名 |
Category |
Target |
構造式 |
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- HY-B1276S
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Metaproterenol-d7 (hemisulfate) is the deuterium labeled Metaproterenol hemisulfate. Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity .
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- HY-W741999
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Metaproterenol-d7-1 (hemisulfate) is deuterium labeled Metaproterenol (hemisulfate). Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity .
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入力情報は安全に管理されます. ※ 必須入力項目.
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