1. Neuronal Signaling
  2. AChE
  3. Physostigmine hemisulfate

Physostigmine hemisulfate (Synonyms: Eserine hemisulfate)

Cat. No.: HY-N2320
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Physostigmine hemisulfate (Eserine hemisulfate) is a potent cholinesterase inhibitor. Physostigmine hemisulfate crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine hemisulfate induces reanimation from isoflurane anesthesia in adult rats.

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Physostigmine hemisulfate Chemical Structure

Physostigmine hemisulfate Chemical Structure

CAS No. : 64-47-1

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Description

Physostigmine hemisulfate (Eserine hemisulfate) is a potent cholinesterase inhibitor. Physostigmine hemisulfate crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine hemisulfate induces reanimation from isoflurane anesthesia in adult rats[1].

In Vivo

Physostigmine hemisulfate (IV; 0.1, 0.2 mg/kg) delays time to emergence from isoflurane anesthesia at doses ≥0.2 mg/kg in male Sprague-Dawley rats[1].

Molecular Weight

324.38

Formula

C₁₅H₂₁N₃O₂.₁/₂H₂O₄S

CAS No.

64-47-1

SMILES

CN1[[email protected]](N(C)CC2)([H])[[email protected]]2(C)C3=C1C=CC(OC(NC)=O)=C3.O=S(O)(O)=O.[1/2]

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Keywords:

Physostigmine hemisulfateEserine hemisulfateAChEAcetylcholinesterasecholinesteraseblood-brainbarriercentralcholinergicneurotransmissionreanimationisofluraneanesthesiaInhibitorinhibitorinhibit

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