1 Result for "

high salt-induced hypertensive rats

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "high salt-induced hypertensive rats" in MCE Product Catalog:

Phytolaccagenin
Phytolaccagenin
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Cat. No.: HY-N1433
CAS No.: 1802-12-6
Category:  

Triterpenes Terpenoids Phytolacca acinosa Roxb. Plants Disease Research Fields Inflammation/Immunology Phytolaccaceae

Target:  

Fungal mAChR Adrenergic Receptor Calcium Channel

Phytolaccagenin is a triterpenoid saponin aglycone, Antifungal agent, vasodilator, antihypertensive agent, and anti-inflammatory agent. Phytolaccagenin activates vascular and cardiac Muscarinic receptors, blocks cardiac β-adrenergic receptors, and inhibits voltage-dependent calcium channels in blood vessels. Phytolaccagenin inhibits the growth of Candida albicans and Cryptococcus neoformans. Phytolaccagenin induces vasodilation, produces negative inotropic and negative chronotropic effects, reduces mean arterial pressure, and inhibits LPS-induced inflammation. Phytolaccagenin exhibits enhanced antihypertensive effects in high salt-induced hypertensive rats. Phytolaccagenin can be used in the research of candidiasis, cryptococcosis, hypertension, and inflammation-related diseases .
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