- Natural Products
- Plants
- Phytolaccaceae
- Phytolacca acinosa Roxb.
Phytolacca acinosa Roxb.
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Phytolacca acinosa Roxb. (12)
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- Formula: C42H66O16
- Molecular Weight: 826.96
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta. Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models, has selective inhibitory activity towards cyclooxygenase-2 (COX-2). Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways.
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- Formula: C31H48O7
- Molecular Weight: 532.71
Phytolaccagenin is a triterpenoid saponin aglycone, Antifungal agent, vasodilator, antihypertensive agent, and anti-inflammatory agent. Phytolaccagenin activates vascular and cardiac Muscarinic receptors, blocks cardiac β-adrenergic receptors, and inhibits voltage-dependent calcium channels in blood vessels. Phytolaccagenin inhibits the growth of Candida albicans and Cryptococcus neoformans. Phytolaccagenin induces vasodilation, produces negative inotropic and negative chronotropic effects, reduces mean arterial pressure, and inhibits LPS-induced inflammation. Phytolaccagenin exhibits enhanced antihypertensive effects in high salt-induced hypertensive rats. Phytolaccagenin can be used in the research of candidiasis, cryptococcosis, hypertension, and inflammation-related diseases.
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- Formula: C48H76O21
- Molecular Weight: 989.10
Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta. Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease. Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression.
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- Formula: C41H64O16
- Molecular Weight: 812.94
Esculentoside F is a triterpene saponin found in the root of Phytolacca acinosa Roxb.
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- Formula: C42H66O16
- Molecular Weight: 826.96
Esculentoside S is a bidesmodic triterpene saponin, found in the leaves of Phytolacca acinosa.
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- Formula: C54H86O24
- Molecular Weight: 1119.25
Esculentoside R (Compound 7) is a triterpenoid saponin (bisdesmoside). Acid hydrolysis of Esculentoside R yields esculentic acid, glucose, xylose and rhamnose.
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- Formula: C42H66O15
- Molecular Weight: 810.98
Esculentoside T is a natural product that can be found in soybeans.
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- Formula: C42H66O15
- Molecular Weight: 810.96
Esculentoside C is a triterpene saponin. Esculentoside C can be obtained from the root of Phytolacca esculenta.
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- Formula: C31H48O7
- Molecular Weight: 532.71
Phytolaccagenin (Standard) is the analytical standard of Phytolaccagenin. This product is intended for research and analytical applications. Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. Phytolcaccagenin has antifungal activity, anti-inflammatory activity and lower toxicity
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- Formula: C42H66O16
- Molecular Weight: 826.96
Esculentoside A (Standard) is the analytical standard of Esculentoside A. This product is intended for research and analytical applications. Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta. Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models, has selective inhibitory activity towards cyclooxygenase-2 (COX-2). Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways.
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