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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
high-mobility group box-1
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "high-mobility group box-1" in MCE Product Catalog:
7
7 Publications Verification
Cat. No.: HY-P70570
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Human
Source:
E. coli
5
5 Cited Publications
Cat. No.: HY-P73104
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Mouse
Source:
HEK293
4
4 Cited Publications
Cat. No.: HY-P73104A
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Mouse
Source:
HEK293
3
3 Cited Publications
Cat. No.: HY-P70274
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Human
Source:
HEK293
2
2 Cited Publications
Research Areas:
Necrocide 1, a necrosis by sodium overload (NECSO) inducer, is a selective transient receptor potential melastatin 4 (TRPM4) agonist with an EC50 of 306.3 nM for human TRPM4. Necrocide 1 triggers TRPM4-dependent necrotic cell death through the induction of sodium influx. Necrocide 1 induces hallmarks of immunogenic cell death incurring calreticulin (CALR) exposure, ATP secretion and high mobility group box 1 (HMGB1) release. Necrocide 1 can be used for the study of breast and prostate cancer .
2
2 Cited Publications
Cat. No.: HY-P72797
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P73102
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Human
Source:
HEK293
1
1 Cited Publications
Target:
Free Radical Scavengers TNF Receptor Interleukin Related Toll-like Receptor (TLR) Reactive Oxygen Species (ROS)
Research Areas:
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research .
1
1 Cited Publications
Cat. No.: HY-P700182AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Mouse
Source:
E. coli
Cat. No.: HY-N2055
CAS No.: 19895-95-5
Cat. No.: HY-177839
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
Liposomal Coenzyme Q10 is an orally effective delivery system that encapsulates fat-soluble Coenzyme Q10 (CoQ10) (HY-N0111) via liposomal nanocarriers. Liposomal Coenzyme Q10 alleviates hepatic oxidative stress, attenuates hepatic inflammatory responses, reduces hepatocyte apoptosis, and ameliorates liver fibrosis. Liposomal Coenzyme Q10 activates the ferroptosis suppressor protein 1 (FSP1)/Coenzyme Q10 system, reduces the accumulation of malondialdehyde and ROS, and inhibits neuronal ferroptosis. Liposomal Coenzyme Q10 can be used in studies related to Propanoic acid (HY-W020017)-induced liver injury and subarachnoid hemorrhage .
Cat. No.: HY-P73103
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Human
Source:
E. coli
Cat. No.: HY-P78139
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Human
Source:
HEK293
Cat. No.: HY-P72797AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Human
Source:
E. coli
Cat. No.: HY-P70274A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Human
Source:
HEK293
Cat. No.: HY-P704283
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HMGB1; Sulfoglucuronyl Carbohydrate Binding Protein; Prev. HMG1; Amphoterin; high mobility group Protein B1; HMG-1; high mobility group Protein 1; Nuclear Dot-Associated Sp100 Protein; SBP-1; Nuclear Autoantigen Sp-100; HMG3; high-mobility group box 1; Hi
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
