6 Results for "

histidyl-tRNA synthetase

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "histidyl-tRNA synthetase" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W014233
CAS No.: 1596-64-1
L-Histidinol dihydrochloride is an orally active histidyl-tRNA synthetase inhibitor. L-Histidinol dihydrochloride interferes with the initiation stage of protein synthesis, thus affecting cell proliferation and metabolism. L-Histidinol dihydrochloride has the effect of modulating the sensitivity of tumor cells to chemotherapeutic agents. L-Histidinol dihydrochloride reduces the toxicity of certain chemotherapeutic agents to normal tissues and enhance the sensitivity of tumor cells to chemotherapeutic agents .
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Cat. No.: HY-E70233
CAS No.: 9068-78-4
Target:  

Others

Research Areas:  

Inflammation/Immunology

Histidyl-tRNA synthetase, human is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. Histidyl-tRNA synthetase has been found to act as a particularly important antigen in autoimmune diseases such as rheumatic arthritis or myositis .
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Cat. No.: HY-W142169
CAS No.: 15191-21-6
Synonyms: Formyl-L-histidine
Research Areas:  

Others

N-Formyl-L-histidine shows binding affinity to histidyl-tRNA synthetase with a Ki value of 4.6 μM. N-Formyl-L-histidine shows a competitive inhibition against L-histidine ammonia-lyase, inhibits urocanic acid formation from L-histidine with a Ki value of 4.26 mM .
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Cat. No.: HY-W064342S
L-Histidinol-d3 ((S)-2-Amino-3-(1H-imidazol-5-yl)propan-1-ol-d3) is the deuterium labeled L-Histidinol (HY-W014233). L-Histidinol is an orally active histidyl-tRNA synthetase inhibitor. L-Histidinol interferes with the initiation stage of protein synthesis, thus affecting cell proliferation and metabolism. L-Histidinol has the effect of modulating the sensitivity of tumor cells to chemotherapeutic agents. L-Histidinol reduces the toxicity of certain chemotherapeutic agents to normal tissues and enhance the sensitivity of tumor cells to chemotherapeutic agents .
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Cat. No.: HY-P73933
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HARS1; Histidine tRNA Ligase 1, Cytoplasmic; Prev. HARS; Histidine Translase; Prev. USH3B; Usher Syndrome 3B; HisRS; Jo‐1 Antigen; Histidine--tRNA Ligase, Cytoplasmic; Jo-1 Antigen; histidyl-tRNA synthetase; CMT2W; HRS; histidyl-tRNA synthetase 1; Histidi
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-W014233R
CAS No.: 1596-64-1
L-Histidinol (dihydrochloride) (Standard) is the analytical standard of L-Histidinol (dihydrochloride) (HY-W014233). This product is intended for research and analytical applications. L-Histidinol dihydrochloride is an orally active histidyl-tRNA synthetase inhibitor. L-Histidinol dihydrochloride interferes with the initiation stage of protein synthesis, thus affecting cell proliferation and metabolism. L-Histidinol dihydrochloride has the effect of modulating the sensitivity of tumor cells to chemotherapeutic agents. L-Histidinol dihydrochloride reduces the toxicity of certain chemotherapeutic agents to normal tissues and enhance the sensitivity of tumor cells to chemotherapeutic agents .
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