11 Results for "

homology-2

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "homology-2" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P3279
CAS No.: 147612-86-0
Target:  

Src

Research Areas:  

Cancer

EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains [2].
loading...
    loading...
Cat. No.: HY-N2521
CAS No.: 52328-97-9
Synonyms: FLLL31
Tetramethylcurcumin (FLLL31), derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects [2].
loading...
    loading...
Cat. No.: HY-151577
CAS No.: 2816059-41-1
Purity:  98.58%
Target:  

STAT Apoptosis

Research Areas:  

Cancer

STAT3-SH2 domain inhibitor 1 is a potent Src Homology 2 (SH2) Domain of STAT3 (STAT3-SH2 domain) inhibitor with a Kd value of 1.57 μM. STAT3-SH2 domain inhibitor 1 inhibits STAT3 signaling transduction and transcriptional activation. STAT3-SH2 domain inhibitor 1 induces apoptosis in gastric cancer cells. STAT3-SH2 domain inhibitor 1 can be used in research of cancer .
loading...
    loading...
Cat. No.: HY-168929
CAS No.: 3113070-25-7
Research Areas:  

Cancer

SHP1 activator 1 (Compound 3n) is an activator for src homology-2 domain-containing protein tyrosine phosphatase 1(SHP1) with an EC50 of 17.66 μM. SHP1 activator 1 inhibits the proliferation of ABC-DLBCL cells, induces apoptosis by inhibiting STAT3 signaling pathway. SHP1 activator 1 emitts blue and green fluorescence signalis in MDA-MB-231 cell, and can be used as a cell imaging agent .
loading...
    loading...
Cat. No.: HY-P82537
Synonyms: BLNK; BASH; SLP65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P82537A
Synonyms: BLNK; BASH; SLP65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-175520
Target:  

SHP2 Phosphatase Apoptosis

Research Areas:  

Cancer

SHP2-IN-42 is a src homology 2 domain-containing phosphatase 2 (SHP2) inhibitor with an IC50 of 15 nM. SHP2-IN-42 inhibits cell proliferation and induces apoptosis and G1 phase cell cycle arrest. SHP2-IN-42 can be used for the research of cancer, such as acute myeloid leukemia (AML) .
loading...
    loading...
Cat. No.: HY-P7667
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BLNK; Bca; B Cell Linker; Src homology [SH2] Domain-Containing Leukocyte Protein Of 65 KD; SLP65; Src homology 2 Domain-Containing Leukocyte Protein Of 65 KDa; BASH; B-Cell Adapter Containing A Src homology 2 Domain Protein; SLP-65; B Cell Adaptor Contain
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P75474
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BLNK; Bca; B Cell Linker; Src homology [SH2] Domain-Containing Leukocyte Protein Of 65 KD; SLP65; Src homology 2 Domain-Containing Leukocyte Protein Of 65 KDa; BASH; B-Cell Adapter Containing A Src homology 2 Domain Protein; SLP-65; B Cell Adaptor Contain
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-D2204
CAS No.: 2956720-62-8
SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe 3+ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM) .
loading...
    loading...
Cat. No.: HY-P82649
Synonyms: SHC1; SHC; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
  • 1