2956720-62-8
2956720-62-8
Chemical Structure
SHP1-IN-1
- CAS No.: 2956720-62-8
- Formula:C22H23N5O4
- Molecular Weight:421.45
InChIKey: QYJFUFUWZGOYLF-UHFFFAOYSA-N
SMILES: COC1=CC=CC(C2=NC3=NC(C4=CC=C(C(C(O)=O)=C4)O)=C(N3N2)NC(C)(C)C)=C1
Biological Activity: SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe3+ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM)[1].
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SHP1-IN-1 | SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe3+ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM). | |||||||||||||||||||||
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References
Keywords
