147612-86-0
147612-86-0
Chemical Structure
EPQpYEEIPIYL
- CAS No.: 147612-86-0
- Formula:C66H97N12O24P
- Molecular Weight:1473.52
InChIKey: DLNQPUNIZRZGQD-VBIHGRSYSA-N
SMILES: O=C(N(CCC1)[C@@H]1C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC(C=C2)=CC=C2O)=O)=O)[C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC3)N3C([C@@H](N)CCC(O)=O)=O)=O)=O)CC(C=C4)=CC=C4O[P](O)(O)=O)=O)=O)=O
Biological Activity: EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains[1][2].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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EPQpYEEIPIYL | 99.49% | EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains. | ||||||||||||||||||||
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References
- [1]. G Payne, et al. The phosphopeptide-binding specificity of Src family SH2 domains. Chem Biol. 1994 Oct;1(2):99-105. [Content Brief]
- [2]. T D Mulhern, et al. The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity. Structure. 1997 Oct 15;5(10):1313-23. [Content Brief]
