26 Results for "

human interleukin-1β

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "human interleukin-1β" in MCE Product Catalog:

58
58 Publications Verification
Cat. No.: HY-P7028
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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9
9 Cited Publications
Cat. No.: HY-P73149
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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7
7 Cited Publications
Cat. No.: HY-P81232
Synonyms: caspase-1 isoform alpha subunit; CASP1; ICE; IL1BC; Caspase-1 subunit p20; CASP 1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BCE; interleukin 1 beta convertase; interleukin 1 beta convertase precursor; interleukin 1 beta converting enzyme; CASP-1; interleukin-1 beta convertase; IL-1BC; interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1_human; CASP1_MOUSE.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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4
4 Cited Publications
Cat. No.: HY-P7205
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-P78459
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P70586
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P78459A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-N12586
CAS No.: 603-17-8
Pheophytin a is a multi-target inhibitor, anticancer agent, antioxidant and antiviral agent. Pheophytin a directly binds to and inhibits HCV-NS3/4A protease (IC50=0.89 μM) to block viral replication. Pheophytin a also scavenges free radicals, reduces ferric ions, and exhibits cytotoxic activity against breast cancer cells. Pheophytin a effectively inhibits LPS-induced production of nitric oxide, prostaglandin E2, NOS2 and COX-2, as well as various pro-inflammatory cytokines, by downregulating the transcription levels of inflammatory mediators and blocking the ERK1/2 and STAT-1 pathways. In a low nerve growth factor environment, Pheophytin a also enhances ERK1/2 phosphorylation and synergistically promotes neurite outgrowth through MAPK pathway. Pheophytin a can be used to investigate the pathogenic mechanisms of diseases including chronic hepatitis C, sepsis, breast cancer and Alzheimer's disease .
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Cat. No.: HY-156202
CAS No.: 35750-48-2
Research Areas:  

Cancer

Geranylgeranoic acid (Compound 5) is inhibits lysine-specific demethylase 1 (LSD1) with an IC50 value of 46.97 µM. Geranylgeranoic acid induces apoptosis via loss of the mitochondrial membrane potential and activation of interleukin-1β-converting enzyme (ICE) and cysteine protease precursor 32 (CPP32) in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes. Geranylgeranoic acid an isoprenoid with anticancer activity, which is found in S. chinensis .
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Cat. No.: HY-P991138
CAS No.: 2981430-39-9
Synonyms: Genakumab; GenSci048; Kinnazumab

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Firsekibart is an immunoglobulin G4-λ2 monoclonal antibody targeting human interleukin 1β (IL-1β). Firsekibart is promising for research of inflammation-related diseases, such as rheumatoid arthritis and inflammatory bowel disease .
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Cat. No.: HY-103291
CAS No.: 126959-88-4
Purity:  99.96%
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .
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Cat. No.: HY-174627
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL1B mRNA encodes the human interleukin 1 beta (IL1B) protein, a member of the interleukin 1 cytokine family. IL1B is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.
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Cat. No.: HY-K2116

MCE HOLO Human Interleukin-1β (IL-1β) Detection Kit is a homogeneous luminescence-based assay used for the quantitative detection of human IL-1β concentrations in biological samples such as buffer solutions, cell culture supernatants, or serum.

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Cat. No.: HY-P992024

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

SK48-E26 is a human interleukin-1β (IL-1β) inhibitor, with a IC50 of 400 pM against human IL-1β, a IC50 of 185 pM against cynomolgus monkey IL-1β, and a Ka value ranging from 0.048 nM to 3 nM for human IL-1β. SK48-E26 binds to the conformational epitope of human IL-1β spanning amino acid residues 95-101, and blocks the biological activity of IL-1β. SK48-E26 can be used in research related to IL-1β-mediated inflammatory diseases and osteoarthritis .
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Cat. No.: HY-125577
CAS No.: 192756-07-3
Synonyms: RU-36384
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

VRT-18858 (RU-36384), the active metabolite of Pralnacasan (HY-19676), is a potent interleukin-1β converting enzyme (ICE) inhibitor (Ki = 1.4 nM). VRT-18858 inhibits LPS (HY-D1056)-induced IL-1β release (IC50 = 0.42 µM) and S. aureus Cowan-induced IL-1β and IL-18 release (IC50=1.3 and 2.1 µM, respectively) in human peripheral blood mononuclear cells. VRT-18858 can be used for osteoarthritis research .
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Cat. No.: HY-P992022

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

AK114 is an anti-human interleukin-1 beta (IL-1β) imonoclonal antibody. AK114 binds to interleukin-1 beta and prevents its binding to the IL-1 receptor, suppresses inflammatory responses, tumorigenesis, and angiogenesis mediated by interleukin-1 beta.AK114 exhibits anti-inflammatory, immunomodulating, and antineoplastic activities .
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Cat. No.: HY-P70586G
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P705432
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P78143
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P700096AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-interleukin-1-Beta; interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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