3 Results for "

iron-deficient conditions

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "iron-deficient conditions" in MCE Product Catalog:

Aerobactin
Aerobactin
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Cat. No.: HY-122280
CAS No.: 26198-65-2
Purity:  97.23%
Category:  

Microorganisms Ketones, Aldehydes, Acids

Target:  

Endogenous Metabolite Reactive Oxygen Species (ROS) Bacterial

Aerobactin is a siderophore produced by bacteria. Aerobactin exhibits the primary activity of chelating ferric ions and transporting them into bacterial cells. Aerobactin promotes bacterial growth, biofilm formation, antioxidant stress resistance, and enhances bacterial virulence and transcellular translocation ability under iron-deficient conditions. Aerobactin is used in research on bacterial infections .
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Nocardamine
Nocardamine
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Cat. No.: HY-124452
CAS No.: 26605-16-3
Purity:  95.00%
Synonyms: Desferrioxamine E; Nocardamin
Nocardamine (Desferrioxamine E; Nocardamin) is a cyclic trihydroxamate siderophore with iron ion chelation, antioxidant, antibacterial and other activities. Nocardamine is synthesized by Pseudomonas stutzeri under iron-deficient conditions, and excessive iron ions significantly inhibit its biosynthesis process. Nocardamine increases the level of phosphorylated ERK protein, promotes nuclear translocation of β-catenin, and restores the downregulated expression of SIRT1 protein. Nocardamine alleviates cellular oxidative stress, reduces ROS content, and simultaneously repairs the ability to form mineralized nodules and the expression of osteogenic markers. Nocardamine induces FoxA gene transcription and protein expression to assist Pseudomonas aeruginosa in iron ion uptake; it also selectively inhibits the proliferation of mycobacteria. Nocardamine induces spindle-shaped morphological changes in BM-N4 insect cells, and sufficient iron ions inhibit this cellular morphological change. Nocardamine is suitable for research related to bacterial infections .
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3-Deoxyanguibactin
3-Deoxyanguibactin
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Cat. No.: HY-186106
CAS No.: 2247437-94-9
Target:  

Bacterial

Research Areas:  

Infection

3-Deoxyanguibactin is a siderophore and Fe(III) chelator/iron delivery agent. 3-Deoxyanguibactin binds Fe(III) with 2:1 stoichiometry in liquid phase, delivers iron into Acinetobacter baumannii cells, and relies on the BauA outer membrane receptor and bau transport system for cellular entry. 3-Deoxyanguibactin can be used for the research of acinetobacter baumannii infection .
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