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Cat. No.: HY-186106

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3-Deoxyanguibactin

3-Deoxyanguibactin is a siderophore and Fe(III) chelator/iron delivery agent. 3-Deoxyanguibactin binds Fe(III) with 2:1 stoichiometry in liquid phase, delivers iron into Acinetobacter baumannii cells, and relies on the BauA outer membrane receptor and bau transport system for cellular entry. 3-Deoxyanguibactin can be used for the research of acinetobacter baumannii infection.

For research use only. We do not sell to patients.

CAS No.: 2247437-94-9
Formula: C₁₅H₁₆N₄O₃S
Molecular Weight:332.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-Deoxyanguibactin Chemical Structure

CAS No.: 2247437-94-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

In Vitro

3-Deoxyanguibactin (100 μM) forms a Fe³⁺-complex that induces characteristic absorption and fluorescence spectral changes, with efficient fluorescence quenching observed upon Fe³⁺ binding^[1].
3-Deoxyanguibactin (0.1-25 μM) stimulates growth of iron-deficient Acinetobacter baumannii ΔbasD, with moderate activity retained at single-digit micromolar ranges^[1].
3-Deoxyanguibactin (0.1-25 μM) does not stimulate growth of iron-deficient Acinetobacter baumannii ΔbauA, demonstrating iron delivery dependence on the BauA outer membrane receptor^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2247437-94-9
Molecular Weight 332.38
Formula C₁₅H₁₆N₄O₃S
SMILES

OC1=C(C=CC=C1)C2=N[C@@H](CS2)C(N(O)CCC3=CN=CN3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Lee H, et al. Synthesis and Characterization of Anguibactin To Reveal Its Competence To Function as a Thermally Stable Surrogate Siderophore for a Gram-Negative Pathogen, Acinetobacter baumannii. Org Lett. 2018;20(20):6476-6479. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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