3-Deoxyanguibactin 

3-Deoxyanguibactin is a siderophore and Fe(III) chelator/iron delivery agent. 3-Deoxyanguibactin binds Fe(III) with 2:1 stoichiometry in liquid phase, delivers iron into Acinetobacter baumannii cells, and relies on the BauA outer membrane receptor and bau transport system for cellular entry. 3-Deoxyanguibactin can be used for the research of acinetobacter baumannii infection^[1].

3-Deoxyanguibactin (100 μM) forms a Fe³⁺-complex that induces characteristic absorption and fluorescence spectral changes, with efficient fluorescence quenching observed upon Fe³⁺ binding^[1].
3-Deoxyanguibactin (0.1-25 μM) stimulates growth of iron-deficient Acinetobacter baumannii ΔbasD, with moderate activity retained at single-digit micromolar ranges^[1].
3-Deoxyanguibactin (0.1-25 μM) does not stimulate growth of iron-deficient Acinetobacter baumannii ΔbauA, demonstrating iron delivery dependence on the BauA outer membrane receptor^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

332.38

C₁₅H₁₆N₄O₃S

2247437-94-9

OC1=C(C=CC=C1)C2=N[C@@H](CS2)C(N(O)CCC3=CN=CN3)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Lee H, et al. Synthesis and Characterization of Anguibactin To Reveal Its Competence To Function as a Thermally Stable Surrogate Siderophore for a Gram-Negative Pathogen, Acinetobacter baumannii. Org Lett. 2018;20(20):6476-6479.  [Content Brief]