34 Results for "

item/HY-B1204

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "item/HY-B1204" in MCE Product Catalog:

  • Targets Recommended:
22
22 Publications Verification
Cat. No.: HY-B1204
CAS No.: 51-45-6
Synonyms: Ergamine
Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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1
1 Cited Publications
Cat. No.: HY-B1204S
CAS No.: 344299-48-5
Synonyms: Ergamine-α,α,β,β-d4 diHYdrochloride
Histamine-α,α,β,β-d4 (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
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Cat. No.: HY-141582
CAS No.: 34354-88-6
Purity:  ≥98.0%
Synonyms: N-Stearoyl pHYtosphingosine
Ceramide 3 (N-Stearoyl phytosphingosine) is an orally active major component of intercellular lipids in the stratum corneum of the skin, and belongs to the ceramide family. Ceramide 3 inhibits c-jun and NF-κB activation induced by Histamine (HY-B1204), and suppresses the expression of IL-4 and TNF-α. Ceramide 3 inhibits scratching behavior and vascular permeability in mice, and exhibits antihistamine effects in guinea pig ileum. Ceramide 3 improves skin barrier function, reduces transepidermal water loss, erythema and the number of circulating epidermal cells, and accelerates barrier repair of irritated or dysfunctional skin .
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Cat. No.: HY-Y0047
CAS No.: 3731-52-0
Synonyms: Picolamine; 3-Pyridinemethanamine; Pyridin-3-ylmethanamine
Research Areas:  

Inflammation/Immunology

3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses) .
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Cat. No.: HY-B1204R
CAS No.: 51-45-6
Synonyms: Ergamine (Standard)
Histamine (Standard) is the analytical standard of Histamine (HY-B1204). This product is intended for research and analytical applications. Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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Cat. No.: HY-W021450A
CAS No.: 100929-81-5
Research Areas:  

Neurological Disease

DL-Fluorocitric acid barium is a glial cell metabolic inhibitor. DL-Fluorocitric acid barium inhibits mechanical hyperalgesia induced by subcutaneous injection of complete Freund's adjuvant in rats. DL-Fluorocitric acid barium inhibits nociceptive behaviors induced by Histamine (HY-B1204) in mice and blocks the phosphorylation of the NMDA receptor NR1 subunit in the lumbar spinal cord of mice. DL-Fluorocitric acid (barium) can be used in the research of mechanical hyperalgesia and nociceptive pain .
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Cat. No.: HY-B1204S1
CAS No.: 751471-48-4
Synonyms: Ergamine-d4
Histamine-d4 (Ergamine-d4) is deuterium labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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Cat. No.: HY-W105318
CAS No.: 608-71-9
Synonyms: PBP
Target:  

TGF-beta/Smad Apoptosis

Research Areas:  

Cancer

Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-β (TGF-β) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-β signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs) .
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Cat. No.: HY-W060470
CAS No.: 35454-39-8
Target:  

Histamine Receptor

Research Areas:  

Neurological Disease

1-Methyl-4-imidazoleacetic acid hydrochloride is a stable metabolite of Histamine (HY-B1204) that is produced by the oxidation of the primary metabolite, N-methylhistamine .
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Cat. No.: HY-145525
CAS No.: 173686-75-4
Synonyms: CAR 18:2; C18:2 Carnitine; L-Carnitine linoleoyl ester
Target:  

Endogenous Metabolite

Research Areas:  

Others

Linoleoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. Hepatic levels of linoleoyl-L-carnitine are increased following high-dose (200 mg/kg) administration of Isoniazid (Item No. 20378) in mice.
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Cat. No.: HY-141582S
CAS No.: 1354806-91-9
Synonyms: N-Stearoyl pHYtosphingosine-d3
Ceramide 3-d3 (N-Stearoyl phytosphingosine-d3) is deuterium labeled Ceramide 3. Ceramide 3 is an orally active major component of intercellular lipids in the stratum corneum of the skin, and belongs to the ceramide family. Ceramide 3 inhibits c-jun and NF-κB activation induced by Histamine (HY-B1204), and suppresses the expression of IL-4 and TNF-α. Ceramide 3 inhibits scratching behavior and vascular permeability in mice, and exhibits antihistamine effects in guinea pig ileum. Ceramide 3 improves skin barrier function, reduces transepidermal water loss, erythema and the number of circulating epidermal cells, and accelerates barrier repair of irritated or dysfunctional skin.
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Cat. No.: HY-B1204S2
Synonyms: Ergamine-13C5, 15N3
Histamine- 13C5, 15N3 (Ergamine- 13C5, 15N3) is the 13C and 15N labeled isotope of Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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Cat. No.: HY-137555
CAS No.: 79250-60-5
Purity:  ≥99.0%
Synonyms: 11-deHYdro-2,3-dinor TXB2
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

11-dehydro-2,3-dinor Thromboxane B2 (11-dehydro-2,3-dinor TXB2) is a metabolite of the TXA2 inactive metabolite TXB2 (Item No. 19030). It is formed from TXB2 by cytosolic aldehyde dehydrogenase (ALDH) and β-oxidation. Levels of 11-dehydro-2,3-dinor TXB2 are increased 5.2-fold in a surgery-induced rat model of tendon overuse.
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Cat. No.: HY-106870
CAS No.: 82227-39-2
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Pibaxizine is an orally active anti-inflammatory agent. Pibaxizine shows antagonist effect on the Histamine (HY-B1204) induced bronchoconstriction. Pibaxizine can be used for the researches of inflammation and immunology, such as asthma .
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Cat. No.: HY-105505
CAS No.: 139339-02-9
KF-17625 is an orally active bronchodilator. KF-17625 can inhibit bronchoconstriction induced by Carbachol (HY-B1208), Histamine (HY-B1204), or Leukotriene D4 (HY-113456). KF-17625 can inhibit canine tracheal phosphodiesterase (PDE) IV (IC50 = 12 μM) and Concanavalin-A (HY-P2149)-induced histamine release from rat mast cells (44% inhibition at 10 mM). KF-17625 can be used for the researches of immunology and inflammation .
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Cat. No.: HY-B1204S4
Synonyms: Ergamine-15N3
Histamine- 15N3 is the 15N3-labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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Cat. No.: HY-W114419
CAS No.: 79-97-0
Bisphenol C is an estrogen receptor-α (ERα) agonist and an ERβ antagonist, with IC50 values of 2.65 nM for ERα and 1.94 nM for ERβ. Bisphenol C is a material of manufacturing polyester polymers like polycarbonate, is widely used in daily items like water bottles, food packaging, textile and so on .
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Cat. No.: HY-P10619
CAS No.: 145194-26-9
Target:  

Neurokinin Receptor

Research Areas:  

Inflammation/Immunology

[Tyr6,D-Phe7,D-His9]-Substance P (6-11) is a tachykinin NK1 receptor antagonist that antagonizes Histamine (HY-B1204) induced hyperalgesia .
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Cat. No.: HY-13936R
CAS No.: 2625-49-2
Synonyms: 1-MetHYlimidazole-4-acetic acid (Standard)
Research Areas:  

Others

1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid) (Standard) is the analytical standard of 1-Methylimidazoleacetic acid. This product is intended for research and analytical applications. 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis .
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Cat. No.: HY-13936S
CAS No.: 122380-33-0
Synonyms: 1-MetHYlimidazole-4-acetic acid-d3
1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid)-d3 is deuterium labeled 1-Methylimidazoleacetic acid (HY-13936). 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis .
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