3 Results for "

latency-associated nuclear antigen (LANA)

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "latency-associated nuclear antigen (LANA)" in MCE Product Catalog:

Cat. No.: HY-155128
CAS No.: 3033110-75-4
Purity:  99.02%
Target:  

HSV

Research Areas:  

Infection

LANA-DNA-IN-2 (Compound 20) is a latency-associated nuclear antigen (LANA)-DNA interaction inhibitor. LANA-DNA-IN-2 can be used for research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection .
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Cat. No.: HY-151380
CAS No.: 2512847-06-0
Purity:  99.68%
Target:  

HSV

Research Areas:  

Infection

LANA-DNA-IN-1 is a potent LANA-DNA inhibitor. LANA-DNA-IN-1 has inhibition activity for LBS2, LBS1 and LBS3 with IC50 values of 8 μM, 9μM and 8μM. LANA-DNA-IN-1shows against wild-type LANA with IC50 value of 53 μM. LANA-DNA-IN-1 can be used for the research of infection .
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Cat. No.: HY-P11137
CAS No.: 878495-58-0
Target:  

HSV

Research Areas:  

Cancer

LANA is a KSHV latency-associated nuclear antigen. The core function of LANA is to act as an "anchor" for the viral genome, attaching it to the chromatin of the host cell. LANA ensures that the episomal DNA of KSHV replicates together with the host chromosome and is evenly distributed among the daughter cells, thereby maintaining the latent infection of the virus in the cell population. LANA can regulate the transcription of viral and host cell genes, and regulate certain host cell genes to promote cell survival. LANA can be used to study the viral DNA tethering structure .
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