LANA-DNA-IN-1 

LANA-DNA-IN-1 is a potent LANA-DNA inhibitor. LANA-DNA-IN-1 has inhibition activity for LBS2, LBS1 and LBS3 with IC₅₀ values of 8 μM, 9μM and 8μM. LANA-DNA-IN-1shows against wild-type LANA with IC₅₀ value of 53 μM. LANA-DNA-IN-1 can be used for the research of infection^[1].

IC50: 8 μM (LBS2); 9μM LBS1); 8 μM (LBS3); 53 μM (wild-type LANA)^[1]

LANA-DNA-IN-1 has inhibition activity for LBS2, LBS1 and LBS3 with IC₅₀ values of 8 μM, 9μM and 8μM in FP Assay^[1].
LANA-DNA-IN-1 has potent LANA-LBS1-inhibitory with an IC₅₀ values of 53 μM^[1].
LANA-DNA-IN-1 (31.25, 62.5, 125 and 250 μM) has potent against wild-type LANA CTD and the oligomerization-deficient LANA DBD mutant^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

330.34

C₁₉H₁₄N₄O₂

2512847-06-0

CC1=CC2=C(C=NC=C2C=C1)N3C=C(N=N3)C4=CC=C(C=C4)C(O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Philine Kirsch, et al. Hit-to-lead optimization of a latency-associated nuclear antigen inhibitor against Kaposi's sarcoma-associated herpesvirus infections. Eur J Med Chem. 2020 Sep 15;202:112525  [Content Brief]