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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
low platelet toxicity
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "low platelet toxicity" in MCE Product Catalog:
Synonyms: Desmorpholinyl ABT-263-NH-Me
Research Areas:
Desmorpholinyl navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is an N-methylamino-substituted derivative of Navitoclax (HY-10087) and a BCL-XL-targeting PROTAC precursor. Desmorpholinyl navitoclax-NH-Me is used for the synthesis of BCL-XL-targeting PROTACs and related research .
PDGFR-IN-1 (compound 7m) is a potent and orally active PDGFR (platelet-derived growth factor receptor) inhibitor, with IC50 values of 2.4 and 0.9 nM for PDGFRα and PDGFRβ, respectively. PDGFR-IN-1 displays robust antitumor effects and low toxicity, and can be used to study osteosarcoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
