1 Result for "

mast cell-mediated inflammatory responses

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "mast cell-mediated inflammatory responses" in MCE Product Catalog:

Cat. No.: HY-189056
CAS No.: 3080682-14-7
Target:  

c-Kit

Research Areas:  

Inflammation/Immunology

Kit-IN-2 is an orally active and highly selective KIT inhibitor. Kit-IN-2 stabilizes the inactive (DFG-out) conformation of KIT. Kit-IN-2 inhibits mast cell-mediated inflammatory responses by blocking stem cell factor-induced ear swelling and vascular permeability in rats. Kit-IN-2 exhibits favorable pharmacokinetic properties in rats. Kit-IN-2 can be used for studies related to acute allergy .
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