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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
membrane permeabilization
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "membrane permeabilization" in MCE Product Catalog:
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4 Cited Publications
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MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC50 of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity .
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3 Cited Publications
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3 Cited Publications
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2 Cited Publications
Cat. No.: HY-135416
CAS No.: 98072-47-0
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1
1 Cited Publications
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MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection .
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1 Cited Publications
Cat. No.: HY-P2460
CAS No.: 172485-26-6
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1 Cited Publications
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Cat. No.: HY-P991669
Synonyms: AML-01
Cat. No.: HY-P5589
CAS No.: 131463-18-8
Synonyms: PlnA
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Cat. No.: HY-D0920
CAS No.: 166196-17-4
Arylquin 1, a prostate-apoptosis-response-4 (Par-4) secretagogue, targets vimentin to induce Par-4 secretion. Arylquin 1 induces non-apoptotic cell death in cancer cells through the induction of lysosomal membrane permeabilization (LMP) .
Cat. No.: HY-P4118
CAS No.: 952754-66-4
Synonyms: Penetrating analog
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Cat. No.: HY-P2302
CAS No.: 136661-76-2
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Cat. No.: HY-131058
CAS No.: 1653999-47-3
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Muscotoxin A is an ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death .
Cat. No.: HY-143335
CAS No.: 2901064-06-8
Antifungal agent 52 (compound 6c) is a tetrazole derivative. Antifungal agent 52 inhibits the synthesis of Ergosterol (HY-N0181). Antifungal agent 52 exhibit a significant antifungal activity against Candida albicans. Antifungal agent 52 affects C. albicans sessile cell membrane permeabilization .
Cat. No.: HY-N15548
CAS No.: 1206881-47-1
Synonyms: Armeniaspirole A
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Cat. No.: HY-175376
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QPyN16Th is an N-palmitoylated cationic thiazolidine antibiotic. QPyN16Th is selectively active against the Gram-positive bavteria E. faecalis, S. aureus and MRSA with an MIC of 1.95 μM over gram-negative bacteria. QPyN16Th can induce membrane permeabilization and depolarization and ROS production in MRSA. QPyN16Th increases the survival of zebrafish model of intramuscular MRSA infection .
Cat. No.: HY-P10614
CAS No.: 300349-78-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
