1592908-75-2
1592908-75-2
Chemical Structure
MSN-50
- CAS No.: 1592908-75-2
- Formula:C36H38BrN3O6
- Molecular Weight:688.61
IUPAC Name: N-((S)-1-((((2R,3S)-3-amino-6-((2-methoxyethoxy)methoxy)-2,3-dihydrobenzofuran-2-yl)methyl)(4-bromobenzyl)amino)-1-oxo-3-phenylpropan-2-yl)benzamide
InChIKey: QRQAGDGLLUPMLV-IGOOQNSHSA-N
SMILES: O=C(C1=CC=CC=C1)N[C@@H](CC2=CC=CC=C2)C(N(CC3=CC=C(C=C3)Br)C[C@H]4OC5=CC(OCOCCOC)=CC=C5[C@@H]4N)=O
Biological Activity: MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MSN-50 | 98.09% | MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.85
HY-120079MSN-125 -
Similarity Score 0.55
HY-W662576KVD-001 -
Similarity Score 0.54
HY-111073Bentysrepinine -
Similarity Score 0.50
HY-158935Dihydro K22 -
Similarity Score 0.50
HY-120846CHIR 4531 -
Similarity Score 0.50
HY-120277TIPP -
Similarity Score 0.50
HY-12645NCL1 -
Similarity Score 0.49
HY-43934Tiropramide hydrochloride -
Similarity Score 0.49
HY-N10863Aurantiamide benzoate -
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References
- [1]. Niu X, et al. A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection. Cell Chem Biol. 2017;24(4):493-506.e5. [Content Brief]
- [2]. Jensen K, et al. Pharmacological inhibition of Bax-induced cell death: Bax-inhibiting peptides and small compounds inhibiting Bax. Exp Biol Med (Maywood). 2019;244(8):621-629. [Content Brief]
