1592908-16-1
Chemical Structure
MSN-125
- CAS No.: 1592908-16-1
- Formula:C36H38BrN3O6
- Molecular Weight:688.61
IUPAC Name: N-((S)-1-(((2R,3S)-2-(aminomethyl)-6-((2-methoxyethoxy)methoxy)-2,3-dihydrobenzofuran-3-yl)(4-bromobenzyl)amino)-1-oxo-3-phenylpropan-2-yl)benzamide
InChIKey: NUPXNNVRTSEHSR-IGOOQNSHSA-N
SMILES: O=C(C1=CC=CC=C1)N[C@@H](CC2=CC=CC=C2)C(N(CC3=CC=C(C=C3)Br)[C@@H]4[C@H](OC5=CC(OCOCCOC)=CC=C45)CN)=O
Biological Activity: MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC50 of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MSN-125 | 99.67% | MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC50 of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity. | ||||||||||||||||||||
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