1. Antibody-drug Conjugate/ADC Related
  2. ADC Cytotoxin
  3. Muscotoxin A

Muscotoxin A 

Cat. No.: HY-131058
Handling Instructions

Muscotoxin A is an ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death.

For research use only. We do not sell to patients.

Muscotoxin A Chemical Structure

Muscotoxin A Chemical Structure

CAS No. : 1653999-47-3

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Description

Muscotoxin A is an ADC cytotoxin. Muscotoxin A is a cytotoxic lipopeptide that permeabilizes mammalian cell membranes and induces necrotic cell death[1].

In Vitro

Muscotoxin A (0-13.2 μM ; 24 hours) is cytotoxic to YAC-1, Sp/2, and HeLa cancer cell lines (LC50) ranged from 9.9 to 13.2 μM, causing membrane damage and influx of calcium ions[1].

Molecular Weight

1211.41

Formula

C₅₈H₉₀N₁₂O₁₆

CAS No.

1653999-47-3

SMILES

O=C(N1CCC[[email protected]]1(C(NC(CC(CCCCC)O)C(O)C(N[[email protected]](CCC(N)=O)C(NCC(N2CCC[[email protected]]2(C(N[[email protected]]3CC4=CC=CC=C4)=O)[H])=O)=O)=O)=O)[H])[[email protected]@]([H])([[email protected]](CC)C)NC([[email protected]](CO)NC(/C(NC([[email protected]](CO)NC([[email protected]@]([H])([[email protected]](CC)C)NC3=O)=O)=O)=C/C)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Muscotoxin AADC CytotoxinCytotoxicYAC-1Sp/2HeLacyanobacteriallipopeptidemammaliancellsInhibitorinhibitorinhibit

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Muscotoxin A
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