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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
214 Results for "
mouse fibroblast
" in MedChemExpress (MCE) Product Catalog:
Products (214)
214 Results for "mouse fibroblast" in MCE Product Catalog:
14
14 Publications Verification
Cat. No.: HY-P7066
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF2; BFGF; Prev. FGFB; Basic fibroblast Growth Factor; fibroblast Growth Factor 2 (Basic); fibroblast Growth Factor; Heparin-Binding Growth Factor 2; Prostatropin; HBGF-2; FGF2A; FGF-2; FGF; fibroblast Growth Factor 2; Basic fibroblast Growth Factor BFGF
10
6
6 Cited Publications
Cat. No.: HY-18601
CAS No.: 1416258-16-6
Target:
Research Areas:
(±)-BI-D is a potent ALLINI (allosteric integrase inhibitor). (±)-BI-D binds integrase at the LEDGF/p75 binding site. (±)-BI-D inhibits HIV-Luc infection in cells (IC50: 0.16 μM in Psip1 knockout E9 mouse embryonic fibroblasts, 2.9 μM in wild-type E9 mouse embryonic fibroblasts) .
5
5 Cited Publications
Cat. No.: HY-P7170
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF10; Produced By fibroblasts Of Urinary Bladder Lamina Propria; fibroblast Growth Factor 10; fibroblast Growth Factor; Keratinocyte Growth Factor 2; LADD3; FGF-10; FGF
5
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4
3
3 Cited Publications
Target:
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TC-I 15 (TC-I-15) is a type of allosteric collagen-binding integrin α2β1 inhibitor, and it also inhibits α1β1 and α11β1. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition. TC-I 15 prevents the formation of a pre-metastatic microenvironment by inhibiting the uptake of cancer-associated fibroblast (CAF) extracellular vesicles (EVs) by lung fibroblasts, which reduces the metastasis of salivary gland adenocystic carcinoma (SACC) to the lungs in mouse models, .
3
3
3 Cited Publications
Cat. No.: HY-P73052
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF2; BFGF; Prev. FGFB; Basic fibroblast Growth Factor; fibroblast Growth Factor 2 (Basic); fibroblast Growth Factor; Heparin-Binding Growth Factor 2; Prostatropin; HBGF-2; FGF2A; FGF-2; FGF; fibroblast Growth Factor 2; Basic fibroblast Growth Factor BFGF
3
3 Cited Publications
Cat. No.: HY-P70533
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF8; HBGF-8; fibroblast Growth Factor 8; FGF-8; AIGF; fibroblast Growth Factor; Androgen-Induced Growth Factor; KAL6; fibroblast Growth Factor 8 (Androgen-Induced); HH6; Heparin-Binding Growth Factor 8; FGF
Species:
Source:
2
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2
2 Cited Publications
Cat. No.: HY-P71084
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A4; fibroblast-Specific Protein-1; Prev. CAPL; Murine Placental Homolog; Prev. MTS1; Protein S100-A4; PEL98; Metastasin 1; P9KA; Protein Mts1; 18A2; Calvasculin; FSP1; Leukemia Multidrug Resistance Associated Protein; 42A; Malignant Transformation Sup
1
1 Cited Publications
Target:
Research Areas:
M47 is a molecular glue that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer .
1
1 Cited Publications
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KL1333, a derivative of β-lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures .
1
1 Cited Publications
Cat. No.: HY-16160
CAS No.: 851636-83-4
Research Areas:
Cysmethynil is an Icmt inhibitor(IC50 = 2.4 μM). Cysmethynil inhibites RAS membrane binding and EGF signal transduction. Cysmethynil prevents the cells in the G1 phase and induces autophagy. Cysmethynil inhibits PC3 cells proliferation, has synergistic effect with Paclitaxel (HY-B0015) and Doxorubicin (HY-15142A). Cysmethynil has anti-tumor effects and can be used for solid tumor (such as prostate cancer et al.) research .
1
1 Cited Publications
Cat. No.: HY-N0008
CAS No.: 21082-33-7
Target:
1
1 Cited Publications
Cat. No.: HY-136093B
CAS No.: 1422365-93-2
Synonyms: IM156 free base; HL156A free base; HL271 free base
Target:
Research Areas:
Lixumistat (IM156 free base) is a potent and orally active AMPK activator and OXPHOS inhibitor. Lixumistat strongly activates AMPK, while it lacks the systemic metabolic regulatory effects of classic metformin, such as hypoglycemic and weight-lowering activities. Lixumistat exhibits significant therapeutic effects on cognitive decline associated with brain aging and pulmonary fibrosis .
1
1 Cited Publications
Synonyms: SB-205607 dihydrobromide
Target:
Research Areas:
TAN-67 (SB-205607) dihydrobromide is a potent and selective nonpeptidic δ-opioid receptor agonist with a Ki value of 0.647 nM. TAN-67 dihydrobromide has neuroprotective effect. TAN-67 dihydrobromide can be used in research of ischemic stroke .
1
1
1 Cited Publications
Cat. No.: HY-P7176
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF7; HBGF-7; fibroblast Growth Factor 7; FGF-7; KGF; fibroblast Growth Factor 7 (Keratinocyte Growth Factor); Keratinocyte Growth Factor; fibroblast Growth Factor; Heparin-Binding Growth Factor 7; FGF
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
